Cultured skin loaded with tetracycline HCl and chloramphenicol as dermal delivery system: Mathematical evaluation of the cultured skin containing antibiotics

Journal of Controlled Release

Volumn 108, Issue 2-3, 2005, Pages 341-350

  Hada, Nobuko ^a   Hasegawa, Tetsuya ^a,b   Takahashi, Hidekazu ^c   Ishibashi, Takuya ^c   Sugibayashi, Kenji ^a  

^a JOSAI UNIVERSITY   (Japan)

^b JOSAI INTERNATIONAL UNIVERSITY   (Japan)

^c TOYOBO CO LTD   (Japan)

Author keywords

Antibiotics; Cultured human skin; Dermal patch; Diffusion model; Drug loaded LSE high

Indexed keywords

ANTIBIOTICS; BIOLOGICAL MEMBRANES; DIFFUSION; DRUG DOSAGE; EPIDEMIOLOGY; PHYSIOLOGICAL MODELS;

CVULTURED HUMAN SKIN; DERMAL PATCH; DIFFUSSION MODEL; DRUG-LOADED LSE-HIGH;

SKIN;

ANTIBIOTIC AGENT; CHLORAMPHENICOL; TETRACYCLINE;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BACTERIUM; CALCULATION; CONTROLLED STUDY; CULTURE MEDIUM; DERMIS; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; EPIDERMIS; EXCISION; HUMAN; HUMAN TISSUE; KINETICS; MALE; MATHEMATICAL ANALYSIS; MEMBRANE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SKIN CULTURE; SKIN INJURY; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; ANIMALS; ANTI-BACTERIAL AGENTS; CHLORAMPHENICOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION; DRUG DELIVERY SYSTEMS; MODELS, STATISTICAL; ORGAN CULTURE TECHNIQUES; RATS; SKIN; SKIN ABSORPTION; SKIN PHYSIOLOGY; SPECTROPHOTOMETRY, ULTRAVIOLET; TETRACYCLINE; WOUND HEALING;

EID: 27744462502     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.08.020     Document Type: Article

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