-
1
-
-
0346434985
-
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, eds, Garland Science: Oxford, United Kingdom
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, (eds). Molecular Biology of the Cell. Garland Science: Oxford, United Kingdom 2002.
-
(2002)
Molecular Biology of the Cell
-
-
-
2
-
-
0004292779
-
-
Maronpot RR, Boorman GA, Gaul BW, eds, Cache River Press: Vienna, Illinois
-
Maronpot RR, Boorman GA, Gaul BW, (eds). Pathology of the Mouse. Cache River Press: Vienna, Illinois 1999.
-
(1999)
Pathology of the Mouse
-
-
-
3
-
-
0037169357
-
Cancer as a complex genetic trait: Tumor susceptibility in humans and mouse models
-
Balmain A. Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models. Cell 2002; 108:145-52.
-
(2002)
Cell
, vol.108
, pp. 145-152
-
-
Balmain, A.1
-
4
-
-
0034003333
-
A critical role for telomeres in suppressing and facilitating carcinogenesis
-
Artandi SE, DePinho RA. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr Opin Genet Dev 2000; 10:39-46.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 39-46
-
-
Artandi, S.E.1
DePinho, R.A.2
-
5
-
-
34247188473
-
Telomere and telomerase in stem cells
-
Hiyama E, Hiyama K. Telomere and telomerase in stem cells. Br J Cancer 2007; 96:1020-4.
-
(2007)
Br J Cancer
, vol.96
, pp. 1020-1024
-
-
Hiyama, E.1
Hiyama, K.2
-
6
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000; 408:433-9.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
7
-
-
0035953308
-
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
-
Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, Schreiber RD. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001; 410:1107-10.
-
(2001)
Nature
, vol.410
, pp. 1107-1110
-
-
Shankaran, V.1
Ikeda, H.2
Bruce, A.T.3
White, J.M.4
Swanson, P.E.5
Old, L.J.6
Schreiber, R.D.7
-
8
-
-
4644335311
-
Cancer: An inflammatory link
-
Balkwill F, Coussens LM. Cancer: an inflammatory link. Nature 2004; 431:405-6.
-
(2004)
Nature
, vol.431
, pp. 405-406
-
-
Balkwill, F.1
Coussens, L.M.2
-
9
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation and cancer
-
Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation and cancer. J Clin Invest 2007; 117:1175-83.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
12
-
-
0033632161
-
Targets of oncogenes and tumor suppressors: Key for understanding basic mechanisms of carcinogenesis
-
Kopnin BP. Targets of oncogenes and tumor suppressors: key for understanding basic mechanisms of carcinogenesis. Biochemistry (Mosc) 2000; 65:2-27.
-
(2000)
Biochemistry (Mosc)
, vol.65
, pp. 2-27
-
-
Kopnin, B.P.1
-
14
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005;436:720-4.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
van der Horst, C.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
15
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguría A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M. Tumour biology: senescence in premalignant tumours. Nature 2005; 436:642.
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguría, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
16
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005; 436:660-5.
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
Rudolph, C.4
Peters, A.H.5
Schlegelberger, B.6
Stein, H.7
Dörken, B.8
Jenuwein, T.9
Schmitt, C.A.10
-
17
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005; 436:725-30.
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
Niki, M.6
Koutcher, J.A.7
Scher, H.I.8
Ludwig, T.9
Gerald, W.10
Cordon-Cardo, C.11
Pandolfi, P.P.12
-
18
-
-
33845292259
-
A negative feedback signaling network underlies oncogene-induced senescence
-
Courtois-Cox S, Genther Williams SM, Reczek EE, Johnson BW, McGillicuddy LT, Johannessen CM, Hollstein PE, MacCollin M, Cichowski K. A negative feedback signaling network underlies oncogene-induced senescence. Cancer Cell 2006; 10:459-72.
-
(2006)
Cancer Cell
, vol.10
, pp. 459-472
-
-
Courtois-Cox, S.1
Genther Williams, S.M.2
Reczek, E.E.3
Johnson, B.W.4
McGillicuddy, L.T.5
Johannessen, C.M.6
Hollstein, P.E.7
MacCollin, M.8
Cichowski, K.9
-
19
-
-
33746427905
-
The von Hippel-Lindau tumor suppressor protein: Roles in cancer and oxygen sensing
-
Kaelin WG. The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing. Cold Spring Harb Symp Quant Biol 2005; 70:159-66.
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 159-166
-
-
Kaelin, W.G.1
-
20
-
-
40949136438
-
The VHL tumor suppressor and HIF: Insights from genetic studies in mice
-
Kapitsinou PP, Haase VH. The VHL tumor suppressor and HIF: insights from genetic studies in mice. Cell Death Differ 2008; 15:650-9.
-
(2008)
Cell Death Differ
, vol.15
, pp. 650-659
-
-
Kapitsinou, P.P.1
Haase, V.H.2
-
21
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza GL. Hypoxia-inducible factor 1 (HIF-1) pathway. Sci STKE 2007; 407:8.
-
(2007)
Sci STKE
, vol.407
, pp. 8
-
-
Semenza, G.L.1
-
22
-
-
39749132878
-
The von hippel-lindau tumor suppressor protein: An update
-
Kaelin WG Jr. The von hippel-lindau tumor suppressor protein: an update. Methods Enzymol 2007; 435:371-83.
-
(2007)
Methods Enzymol
, vol.435
, pp. 371-383
-
-
Kaelin Jr., W.G.1
-
23
-
-
0030847165
-
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice
-
Gnarra JR, Ward JM, Porter FD, Wagner JR, Devor DE, Grinberg A, Emmert-Buck MR, Westphal H, Klausner RD, Linehan WM. Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice. Proc Natl Acad Sci USA 1997; 94:9102-7.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9102-9107
-
-
Gnarra, J.R.1
Ward, J.M.2
Porter, F.D.3
Wagner, J.R.4
Devor, D.E.5
Grinberg, A.6
Emmert-Buck, M.R.7
Westphal, H.8
Klausner, R.D.9
Linehan, W.M.10
-
24
-
-
40249100323
-
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
-
Young AP, Schlisio S, Minamishima YA, Zhang Q, Li L, Grisanzio C, Signoretti S, Kaelin WG Jr. VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. Nat Cell Biol 2008; 10:361-9.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 361-369
-
-
Young, A.P.1
Schlisio, S.2
Minamishima, Y.A.3
Zhang, Q.4
Li, L.5
Grisanzio, C.6
Signoretti, S.7
Kaelin Jr, W.G.8
-
25
-
-
36248945117
-
Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation
-
Lomb DJ, Straub JA, Freeman RS. Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation. J Neurochem 2007; 103:1897-906.
-
(2007)
J Neurochem
, vol.103
, pp. 1897-1906
-
-
Lomb, D.J.1
Straub, J.A.2
Freeman, R.S.3
-
27
-
-
0025287564
-
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product
-
Kaelin WG Jr, Ewen ME, Livingston DM. Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product. Mol Cell Biol 1990; 10:3761-9.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 3761-3769
-
-
Kaelin Jr, W.G.1
Ewen, M.E.2
Livingston, D.M.3
-
28
-
-
33747496717
-
Cyclin-dependent kinase inhibitors in yeast, animals and plants: A functional comparison
-
De Clercq A, Inzé D. Cyclin-dependent kinase inhibitors in yeast, animals and plants: a functional comparison. Crit Rev Biochem Mol Biol 2006; 41:293-313.
-
(2006)
Crit Rev Biochem Mol Biol
, vol.41
, pp. 293-313
-
-
De Clercq, A.1
Inzé, D.2
-
30
-
-
12144283456
-
The p400 E1A-associated protein is a novel component of the p53→p21 senescence pathway
-
Chan HM, Narita M, Lowe SW, Livingston DM. The p400 E1A-associated protein is a novel component of the p53→p21 senescence pathway. Genes Dev 2005; 19:196-201.
-
(2005)
Genes Dev
, vol.19
, pp. 196-201
-
-
Chan, H.M.1
Narita, M.2
Lowe, S.W.3
Livingston, D.M.4
-
31
-
-
17044452288
-
HIF activation identifies early lesions in VHL kidneys: Evidence for site-specific tumor suppressor function in the nephron
-
Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell 2002; 1:459-68.
-
(2002)
Cancer Cell
, vol.1
, pp. 459-468
-
-
Mandriota, S.J.1
Turner, K.J.2
Davies, D.R.3
Murray, P.G.4
Morgan, N.V.5
Sowter, H.M.6
Wykoff, C.C.7
Maher, E.R.8
Harris, A.L.9
Ratcliffe, P.J.10
Maxwell, P.H.11
-
32
-
-
0028800884
-
Prevalence of microscopic lesions in grossly normal renal parenchyma from patients with von Hippel-Lindau disease, sporadic renal cell carcinoma and no renal disease: Clinical implications
-
Walther MM, Lubensky IA, Venzon D, Zbar B, Linehan WM. Prevalence of microscopic lesions in grossly normal renal parenchyma from patients with von Hippel-Lindau disease, sporadic renal cell carcinoma and no renal disease: clinical implications. J Urol 1995; 154:2010-4.
-
(1995)
J Urol
, vol.154
, pp. 2010-2014
-
-
Walther, M.M.1
Lubensky, I.A.2
Venzon, D.3
Zbar, B.4
Linehan, W.M.5
-
33
-
-
0035852668
-
Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor
-
Haase VH, Glickman JN, Socolovsky M, Jaenisch R. Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proc Natl Acad Sci USA 2001; 98:1583-8.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1583-1588
-
-
Haase, V.H.1
Glickman, J.N.2
Socolovsky, M.3
Jaenisch, R.4
-
34
-
-
33645070535
-
Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor
-
Rankin EB, Tomaszewski JE, Haase VH. Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Cancer Res 2006; 66:2576-83.
-
(2006)
Cancer Res
, vol.66
, pp. 2576-2583
-
-
Rankin, E.B.1
Tomaszewski, J.E.2
Haase, V.H.3
-
35
-
-
0141816848
-
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene
-
Ma W, Tessarollo L, Hong SB, Baba M, Southon E, Back TC, et al. Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene. Cancer Res 2003; 63:5320-8.
-
(2003)
Cancer Res
, vol.63
, pp. 5320-5328
-
-
Ma, W.1
Tessarollo, L.2
Hong, S.B.3
Baba, M.4
Southon, E.5
Back, T.C.6
-
36
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
37
-
-
0036167650
-
A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence
-
Peeper DS, Shvarts A, Brummelkamp T, Douma S, Koh EY, Daley GQ, Bernards R. A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence. Nat Cell Biol 2002; 4:148-53.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 148-153
-
-
Peeper, D.S.1
Shvarts, A.2
Brummelkamp, T.3
Douma, S.4
Koh, E.Y.5
Daley, G.Q.6
Bernards, R.7
|