Modeling time variant distributions of cellular lifespans: Increases in circulating reticulocyte lifespans following double phlebotomies in sheep

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 35, Issue 3, 2008, Pages 285-323

  Freise, Kevin J ^a   Widness, John A ^b   Schmidt, Robert L ^b   Veng Pedersen, Peter ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Anemia; Blood cells; Cellular transformations; Convolution; Erythropoiesis; Hematology; Mean potential lifespan; Pharmacokinetics; Survival analysis; Systems analysis; Time variant kinetics

Indexed keywords

ERYTHROPOIETIN;

ANEMIA; ANIMAL CELL; ARTICLE; BODY WEIGHT; CALCULATION; CELL SURVIVAL; CELL TRANSFORMATION; ERYTHROCYTE LIFESPAN; ERYTHROPOIESIS; MATHEMATICAL ANALYSIS; MODEL; NONHUMAN; PARAMETER; PHARMACODYNAMICS; PHLEBOTOMY; PRIORITY JOURNAL; PROBABILITY; RETICULOCYTE; SHEEP; SYSTEM ANALYSIS; TIME; VARIANCE;

ALGORITHMS; ANIMALS; BLOOD VOLUME; BODY WEIGHT; CELL CYCLE; COMPUTER SIMULATION; ERYTHROCYTE COUNT; ERYTHROCYTES; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN; MODELS, STATISTICAL; PHARMACOKINETICS; PHLEBOTOMY; RETICULOCYTES; SHEEP;

EID: 47149100859     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-008-9089-1     Document Type: Article

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