Pharmacodynamic models for agents that alter production of natural cells with various distributions of lifespans

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 33, Issue 2, 2006, Pages 125-166

  Krzyzanski, Wojciech ^a   Woo, Sukyung ^a   Jusko, William J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cell lifespans; Convolution; Erythropoietin; Indirect response models; Pharmacodynamics

Indexed keywords

RECOMBINANT ERYTHROPOIETIN;

ANALYTICAL PARAMETERS; ARTICLE; BLOOD; CALCULATION; CELL LOSS; CELL POPULATION; CELL STIMULATION; CELL SURVIVAL; DENSITY FUNCTIONAL THEORY; DRUG EFFICACY; DRUG POTENCY; INDIRECT PHARMACODYNAMIC RESPONSE MODEL; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROBABILITY; RETICULOCYTE; SINGLE DRUG DOSE; STEM CELL;

ALGORITHMS; CELL PROLIFERATION; CELL SURVIVAL; ERYTHROPOIETIN, RECOMBINANT; GROWTH SUBSTANCES; HUMANS; MODELS, BIOLOGICAL; RETICULOCYTES; STATISTICAL DISTRIBUTIONS; STEM CELLS;

EID: 33645799468     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-006-9007-3     Document Type: Article

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