(-)-Anonaine induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells

Food and Chemical Toxicology

Volumn 46, Issue 8, 2008, Pages 2694-2702

  Chen, Chung Yi ^a   Liu, Tsan Zon ^b   Tseng, Wei Chang ^a   Lu, Fung Jou ^c   Hung, Ray Ping ^a   Chen, Chi Hung ^d   Chen, Ching Hsein ^d  

^a FOOYIN UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

m; ( ) Anonaine; 4,5 diaminofluorescein; Apoptosis; Bax; Caspases; Cervical cancer; DAF 2; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; glutathione; GSH; Madin Darby canine kidney; MDCK; mitochondrial transmembrane potential; N acetylcysteine; NAC; nitric oxide; NO; PI; propidium iodide; reactive oxygen species; ROS

Indexed keywords

ANONAINE; CASPASE; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; DNA; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LEVEL; CELL STRAIN; CELL STRUCTURE; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME DEGRADATION; FEMALE; GLUTATHIONE METABOLISM; HELA CELL; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; UTERINE CERVIX CANCER; VERO CELL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; APORPHINES; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL CYCLE; CELL LINE, TUMOR; DIOXOLES; FLOW CYTOMETRY; GLUTATHIONE; HELA CELLS; HUMANS; IN SITU NICK-END LABELING; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; NITRIC OXIDE; PLANT EXTRACTS; PLANT LEAVES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

BOVINAE;

EID: 47149092365     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.04.024     Document Type: Article

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