Vascular activity of (-)-anonaine, (-)-roemerine and (-)-pukateine, three natural 6a(R)-1,2-methylenedioxyaporphines with different affinities for α1-adrenoceptor subtypes

Planta Medica

Volumn 70, Issue 7, 2004, Pages 603-609

  Valiente, M ^a,d   D'Ocon, P ^a   Noguera, M A ^a   Cassels, B K ^b   Lugnier, C ^c   Ivorra, M D ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

1,2 Methylenedioxyaporphines; Cyclic nucleotide phosphodiesterases; Human cloned 1 adrenoceptor subtypes; Rat aorta; Rat caudal artery; Rat cerebral cortex

Indexed keywords

ALKALOID DERIVATIVE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANONAINE; APOREINE; APORPHINE DERIVATIVE; CALCIUM; CARBON 11; DILTIAZEM; INOSITOL PHOSPHATE; NITROGEN; NORADRENALIN; PHOSPHODIESTERASE; POTASSIUM CHLORIDE; PRAZOSIN; PUKATIENE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; FEMALE; FIBROBLAST; METHYLATION; MOLECULAR CLONING; NONHUMAN; PROTON TRANSPORT; RAT; RECEPTOR AFFINITY; SMOOTH MUSCLE; TAIL ARTERY; VASODILATATION;

ALKALOIDS; ANIMALS; AORTA, THORACIC; APORPHINES; ARTERIES; CALCIUM CHANNELS; CEREBRAL CORTEX; DIOXOLES; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; ISOQUINOLINES; MUSCLE, SMOOTH, VASCULAR; PHOSPHODIESTERASE INHIBITORS; PHYTOTHERAPY; PLANTS, MEDICINAL; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA;

ANIMALIA; BOVINAE;

EID: 3543042553     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-827181     Document Type: Article

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