-
1
-
-
0034594978
-
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
-
Tanaka H., Arakawa H., Yamaguchi T., Shiraishi K., Fukuda S., Matsui K., Takei Y., and Nakamura Y. A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature 404 (2000) 42-49
-
(2000)
Nature
, vol.404
, pp. 42-49
-
-
Tanaka, H.1
Arakawa, H.2
Yamaguchi, T.3
Shiraishi, K.4
Fukuda, S.5
Matsui, K.6
Takei, Y.7
Nakamura, Y.8
-
2
-
-
0035798630
-
Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells
-
Guittet O., Håkansson P., Voevodskaya N., Fridd S., Gräslund A., Arakawa H., Nakamura Y., and Thelander L. Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. J. Biol. Chem. 276 (2001) 40647-40651
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40647-40651
-
-
Guittet, O.1
Håkansson, P.2
Voevodskaya, N.3
Fridd, S.4
Gräslund, A.5
Arakawa, H.6
Nakamura, Y.7
Thelander, L.8
-
3
-
-
0242317756
-
Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis
-
Chabes A.L., Pfleger C.M., Kirschner M.W., and Thelander L. Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis. Proc. Natl. Acad. Sci. USA 100 (2003) 3925-3929
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3925-3929
-
-
Chabes, A.L.1
Pfleger, C.M.2
Kirschner, M.W.3
Thelander, L.4
-
4
-
-
0029793328
-
Induction of the mouse ribonucleotide reductase R1 and R2 genes in response to DNA damage by UV light
-
Filatov D., Björklund S., Johansson E., and Thelander L. Induction of the mouse ribonucleotide reductase R1 and R2 genes in response to DNA damage by UV light. J. Biol. Chem. 271 (1996) 23698-23704
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 23698-23704
-
-
Filatov, D.1
Björklund, S.2
Johansson, E.3
Thelander, L.4
-
5
-
-
0142250911
-
The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53
-
Zhou B.S., Liu X.Y., Mo X.L., Xue L.J., Darwish D., Qiu W.H., Shih J., Hwu E.B., Luh F., and Yen Y. The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53. Cancer Res. 63 (2003) 6583-6594
-
(2003)
Cancer Res.
, vol.63
, pp. 6583-6594
-
-
Zhou, B.S.1
Liu, X.Y.2
Mo, X.L.3
Xue, L.J.4
Darwish, D.5
Qiu, W.H.6
Shih, J.7
Hwu, E.B.8
Luh, F.9
Yen, Y.10
-
6
-
-
31544442476
-
Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells
-
Tsai M.H., Chen X., Chandramouli G.V., Chen Y., Yan H., Zhao S., Keng P., Liber H.L., Coleman C.N., Mitchell J.B., and Chuang E.Y. Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells. Oncogene 25 (2006) 622-632
-
(2006)
Oncogene
, vol.25
, pp. 622-632
-
-
Tsai, M.H.1
Chen, X.2
Chandramouli, G.V.3
Chen, Y.4
Yan, H.5
Zhao, S.6
Keng, P.7
Liber, H.L.8
Coleman, C.N.9
Mitchell, J.B.10
Chuang, E.Y.11
-
7
-
-
1942517876
-
p53: 25 years after its discovery
-
Hofseth L.J., Hussain S.P., and Harris C.C. p53: 25 years after its discovery. TIPS 25 (2004) 177-181
-
(2004)
TIPS
, vol.25
, pp. 177-181
-
-
Hofseth, L.J.1
Hussain, S.P.2
Harris, C.C.3
-
8
-
-
33847390640
-
One two three--p53 p63 p73 and chemosensitivity
-
Müller M., Schleithoff E.S., Stremmel W., Melino G., Krammer P.H., and Schilling T. One two three--p53 p63 p73 and chemosensitivity. Drug Resist. Updat. 9 (2006) 288-306
-
(2006)
Drug Resist. Updat.
, vol.9
, pp. 288-306
-
-
Müller, M.1
Schleithoff, E.S.2
Stremmel, W.3
Melino, G.4
Krammer, P.H.5
Schilling, T.6
-
9
-
-
33646798450
-
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress
-
Murray-Zmijewski F., Lane D.P., and Bourdon J.C. p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ. 13 (2006) 962-972
-
(2006)
Cell Death Differ.
, vol.13
, pp. 962-972
-
-
Murray-Zmijewski, F.1
Lane, D.P.2
Bourdon, J.C.3
-
10
-
-
2442494895
-
The common and distinct target genes of the p53 family transcription factors
-
Harms K., Nozell S., and Chen X. The common and distinct target genes of the p53 family transcription factors. Cell. Mol. Life Sci. 61 (2004) 822-842
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 822-842
-
-
Harms, K.1
Nozell, S.2
Chen, X.3
-
11
-
-
0042166135
-
Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools
-
Kimura T., Takeda S., Sagiya Y., Gotoh M., Nakamura Y., and Arakawa H. Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nat. Genet. 34 (2003) 440-445
-
(2003)
Nat. Genet.
, vol.34
, pp. 440-445
-
-
Kimura, T.1
Takeda, S.2
Sagiya, Y.3
Gotoh, M.4
Nakamura, Y.5
Arakawa, H.6
-
12
-
-
0037051690
-
Expression and mutation analyses of P53R2 a newly identified p53 target for DNA repair in human gastric carcinoma
-
Byun D.S., Chae K.S., Ryu B.K., Lee M.G., and Chi S.G. Expression and mutation analyses of P53R2 a newly identified p53 target for DNA repair in human gastric carcinoma. Int. J. Cancer 98 (2002) 718-723
-
(2002)
Int. J. Cancer
, vol.98
, pp. 718-723
-
-
Byun, D.S.1
Chae, K.S.2
Ryu, B.K.3
Lee, M.G.4
Chi, S.G.5
-
13
-
-
0034738967
-
A ribonucleotide reductase gene is a transcriptional target of p53 and p73
-
Nakano K., Balint E., Ashcroft M., and Vousden K.H. A ribonucleotide reductase gene is a transcriptional target of p53 and p73. Oncogene 19 (2000) 4283-4289
-
(2000)
Oncogene
, vol.19
, pp. 4283-4289
-
-
Nakano, K.1
Balint, E.2
Ashcroft, M.3
Vousden, K.H.4
-
14
-
-
23944463399
-
p73 functionally replaces p53 in Adriamycin-treated p53-deficient breast cancer cells
-
Vayssade M., Haddada H., Faridoni Laurens L., Tourpin S., Valent A., Benard J., and Ahomadegbe J.C. p73 functionally replaces p53 in Adriamycin-treated p53-deficient breast cancer cells. Int. J. Cancer 116 (2005) 860-869
-
(2005)
Int. J. Cancer
, vol.116
, pp. 860-869
-
-
Vayssade, M.1
Haddada, H.2
Faridoni Laurens, L.3
Tourpin, S.4
Valent, A.5
Benard, J.6
Ahomadegbe, J.C.7
-
15
-
-
18844430787
-
Silencing of the p53R2 gene by RNA interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells
-
Yanamoto S., Iwamoto T., Kawasaki G., Yoshitomi I., Baba N., and Mizuno A. Silencing of the p53R2 gene by RNA interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells. Cancer Lett. 223 (2005) 67-76
-
(2005)
Cancer Lett.
, vol.223
, pp. 67-76
-
-
Yanamoto, S.1
Iwamoto, T.2
Kawasaki, G.3
Yoshitomi, I.4
Baba, N.5
Mizuno, A.6
-
16
-
-
34447118849
-
p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage
-
Pontarin G., Ferraro P., Håkansson P., Thelander L., Reichard P., and Bianchi V. p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage. J. Biol. Chem. 282 (2007) 16820-16828
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16820-16828
-
-
Pontarin, G.1
Ferraro, P.2
Håkansson, P.3
Thelander, L.4
Reichard, P.5
Bianchi, V.6
-
17
-
-
34249811206
-
Mutation of RRM2B encoding p53-controlled ribonucleotide reductase (p53R2) causes severe mitochondrial DNA depletion
-
Bourdon A., Minai L., Serre V., Jais J.P., Sarzi E., Aubert S., Chretien D., de Lonlay P., Paquis-Flucklinger V., Arakawa H., Nakamura Y., Munnich A., and Rötig A. Mutation of RRM2B encoding p53-controlled ribonucleotide reductase (p53R2) causes severe mitochondrial DNA depletion. Nat. Genet. 39 (2007) 776-780
-
(2007)
Nat. Genet.
, vol.39
, pp. 776-780
-
-
Bourdon, A.1
Minai, L.2
Serre, V.3
Jais, J.P.4
Sarzi, E.5
Aubert, S.6
Chretien, D.7
de Lonlay, P.8
Paquis-Flucklinger, V.9
Arakawa, H.10
Nakamura, Y.11
Munnich, A.12
Rötig, A.13
-
18
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan C. Nitric oxide and the immune response. Nat. Immunol. 2 (2001) 907-916
-
(2001)
Nat. Immunol.
, vol.2
, pp. 907-916
-
-
Bogdan, C.1
-
19
-
-
18244422745
-
Genetic and epigenetic damage induced by reactive nitrogen species: implications in carcinogenesis
-
Ohshima H. Genetic and epigenetic damage induced by reactive nitrogen species: implications in carcinogenesis. Toxicol. Lett. 140-141 (2003) 99-104
-
(2003)
Toxicol. Lett.
, vol.140-141
, pp. 99-104
-
-
Ohshima, H.1
-
20
-
-
1042298162
-
Reactive nitrogen species in the chemical biology of inflammation
-
Dedon P.C., and Tannenbaum S.R. Reactive nitrogen species in the chemical biology of inflammation. Arch. Biochem. Biophys. 423 (2004) 12-22
-
(2004)
Arch. Biochem. Biophys.
, vol.423
, pp. 12-22
-
-
Dedon, P.C.1
Tannenbaum, S.R.2
-
21
-
-
17544375439
-
Viral mutation accelerated by nitric oxide production during infection in vivo
-
Akaike T., Fujii S., Kato A., Yoshitake J., Miyamoto Y., Sawa T., Okamoto S., Suga M., Asakawa M., Nagai Y., and Maeda H. Viral mutation accelerated by nitric oxide production during infection in vivo. FASEB J. 14 (2000) 1447-1454
-
(2000)
FASEB J.
, vol.14
, pp. 1447-1454
-
-
Akaike, T.1
Fujii, S.2
Kato, A.3
Yoshitake, J.4
Miyamoto, Y.5
Sawa, T.6
Okamoto, S.7
Suga, M.8
Asakawa, M.9
Nagai, Y.10
Maeda, H.11
-
22
-
-
17744371147
-
Inducible nitric oxide synthase-dependent DNA damage in mouse model of inflammatory bowel disease
-
Ding X.H., Hiraku Y., Ma N., Kato T., Saito K., Nagahama M., Semba R., Kuribayashi K., and Kawanishi S. Inducible nitric oxide synthase-dependent DNA damage in mouse model of inflammatory bowel disease. Cancer Sci. 96 (2005) 157-163
-
(2005)
Cancer Sci.
, vol.96
, pp. 157-163
-
-
Ding, X.H.1
Hiraku, Y.2
Ma, N.3
Kato, T.4
Saito, K.5
Nagahama, M.6
Semba, R.7
Kuribayashi, K.8
Kawanishi, S.9
-
23
-
-
0037422535
-
Nitric oxide-induced cellular stress and p53 activation in chronic inflammation
-
Hofseth L.J., Saito S., Hussain S.P., Espey M.G., Miranda K.M., Araki Y., Jhappan C., Higashimoto Y., He P.J., Linke S.P., Quezado M.M., Zurer I., Rotter V., Wink D.A., Appella E., and Harris C.C. Nitric oxide-induced cellular stress and p53 activation in chronic inflammation. Proc. Natl. Acad. Sci. USA 100 (2003) 143-148
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 143-148
-
-
Hofseth, L.J.1
Saito, S.2
Hussain, S.P.3
Espey, M.G.4
Miranda, K.M.5
Araki, Y.6
Jhappan, C.7
Higashimoto, Y.8
He, P.J.9
Linke, S.P.10
Quezado, M.M.11
Zurer, I.12
Rotter, V.13
Wink, D.A.14
Appella, E.15
Harris, C.C.16
-
24
-
-
0038359369
-
Nitric oxide induces phosphorylation of p53 and impairs nuclear export
-
Schneiderhan N., Budde A., Zhang Y.P., and Brüne B. Nitric oxide induces phosphorylation of p53 and impairs nuclear export. Oncogene 22 (2003) 2857-2868
-
(2003)
Oncogene
, vol.22
, pp. 2857-2868
-
-
Schneiderhan, N.1
Budde, A.2
Zhang, Y.P.3
Brüne, B.4
-
25
-
-
0037031848
-
p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NF kappa B-dependent transcription and stabilization by serine 15 phosphorylation
-
Kim S.J., Hwang S.G., Shin D.Y., Kang S.S., and Chun J.S. p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NF kappa B-dependent transcription and stabilization by serine 15 phosphorylation. J. Biol. Chem. 277 (2002) 33501-33508
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33501-33508
-
-
Kim, S.J.1
Hwang, S.G.2
Shin, D.Y.3
Kang, S.S.4
Chun, J.S.5
-
26
-
-
0037013199
-
p53 activation by nitric oxide involves down-regulation of Mdm2
-
Wang X.J., Michael D., de Murcia G., and Oren M. p53 activation by nitric oxide involves down-regulation of Mdm2. J. Biol. Chem. 277 (2002) 15697-15702
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15697-15702
-
-
Wang, X.J.1
Michael, D.2
de Murcia, G.3
Oren, M.4
-
27
-
-
1242328665
-
Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide
-
Roy B., Guittet O., Beuneu C., Lemaire G., and Lepoivre M. Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide. Free Radic. Biol. Med. 36 (2004) 507-516
-
(2004)
Free Radic. Biol. Med.
, vol.36
, pp. 507-516
-
-
Roy, B.1
Guittet, O.2
Beuneu, C.3
Lemaire, G.4
Lepoivre, M.5
-
28
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp T.R., Bernards R., and Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296 (2002) 550-553
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
29
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker S.J., Markowitz S., Fearon E.R., Willson J.K., and Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249 (1990) 912-915
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.4
Vogelstein, B.5
-
30
-
-
0038190875
-
Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73
-
Stiewe T., Stanelle J., Theseling C.C., Pollmeier B., Beitzinger M., and Pützer B.M. Inactivation of retinoblastoma (RB) tumor suppressor by oncogenic isoforms of the p53 family member p73. J. Biol. Chem. 278 (2003) 14230-14236
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14230-14236
-
-
Stiewe, T.1
Stanelle, J.2
Theseling, C.C.3
Pollmeier, B.4
Beitzinger, M.5
Pützer, B.M.6
-
31
-
-
8944232107
-
Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells
-
Bacus S.S., Yarden Y., Oren M., Chin D.M., Lyass L., Zelnick C.R., Kazarov A., Toyofuku W., Gray-Bablin J., Beerli R.R., Hynes N.E., Nikiforov M., Haffner R., Gudkov A., and Keyomarsi K. Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells. Oncogene 12 (1996) 2535-2547
-
(1996)
Oncogene
, vol.12
, pp. 2535-2547
-
-
Bacus, S.S.1
Yarden, Y.2
Oren, M.3
Chin, D.M.4
Lyass, L.5
Zelnick, C.R.6
Kazarov, A.7
Toyofuku, W.8
Gray-Bablin, J.9
Beerli, R.R.10
Hynes, N.E.11
Nikiforov, M.12
Haffner, R.13
Gudkov, A.14
Keyomarsi, K.15
-
32
-
-
33646359442
-
Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells
-
Håkansson P., Hofer A., and Thelander L. Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells. J. Biol. Chem. 281 (2006) 7834-7841
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7834-7841
-
-
Håkansson, P.1
Hofer, A.2
Thelander, L.3
-
33
-
-
34250654965
-
The comet assay: a method to measure DNA damage in individual cells
-
Olive P.L., and Banath J.P. The comet assay: a method to measure DNA damage in individual cells. Nat. Protoc. 1 (2006) 23-29
-
(2006)
Nat. Protoc.
, vol.1
, pp. 23-29
-
-
Olive, P.L.1
Banath, J.P.2
-
34
-
-
0142242181
-
Nitric oxide activates diverse signaling pathways to regulate gene expression
-
Hemish J., Nakaya N., Mittal V., and Enikolopov G. Nitric oxide activates diverse signaling pathways to regulate gene expression. J. Biol. Chem. 278 (2003) 42321-42329
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42321-42329
-
-
Hemish, J.1
Nakaya, N.2
Mittal, V.3
Enikolopov, G.4
-
35
-
-
25644455941
-
The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells
-
Liu X.Y., Zhou B.S., Xue L.J., Shih J., Tye K., Qi C., and Yen Y. The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells. Biochem. Pharmacol. 70 (2005) 1288-1297
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 1288-1297
-
-
Liu, X.Y.1
Zhou, B.S.2
Xue, L.J.3
Shih, J.4
Tye, K.5
Qi, C.6
Yen, Y.7
-
36
-
-
18244402691
-
Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53
-
Grob T.J., Novak U., Maisse C., Barcaroli D., Luthi A.U., Pirnia F., Hugli B., Graber H.U., De Laurenzi V., Fey M.F., Melino G., and Tobler A. Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53. Cell Death Differ. 8 (2001) 1213-1223
-
(2001)
Cell Death Differ.
, vol.8
, pp. 1213-1223
-
-
Grob, T.J.1
Novak, U.2
Maisse, C.3
Barcaroli, D.4
Luthi, A.U.5
Pirnia, F.6
Hugli, B.7
Graber, H.U.8
De Laurenzi, V.9
Fey, M.F.10
Melino, G.11
Tobler, A.12
|