Identification of a minimal functional linker in human topoisomerase I by domain swapping with Cre recombinase

Biochemistry

Volumn 47, Issue 27, 2008, Pages 7127-7136

  Frøhlich, Rikke From ^a   Juul, Sissel ^a   Nielsen, Maria Bjerre ^a   Vinther, Maria ^a   Veigaard, Christopher ^a,b   Hede, Marianne Smedegaard ^a,c   Andersen, Félicie Faucon ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINATION; AMINES; ORGANIC ACIDS;

(MIN ,MAX ,+) FUNCTIONS; AMERICAN CHEMICAL SOCIETY (ACS); CRE RECOMBINASE; DOMAIN SWAPPING; HUMAN TOPOISOMERASE; IN VITRO CHARACTERIZATION; N TERMINALS; RECOMBINASES; TOPO ISOMERASE; TOPOISOMERASES (TOPOS); TYROSINE (TYR);

AMINO ACIDS;

AMINO ACID; CRE RECOMBINASE; DNA TOPOISOMERASE; HYDROGEN PEROXIDE; TYROSINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; CHIMERA; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION;

CAMPTOTHECIN; DNA; DNA TOPOISOMERASES, TYPE I; HUMANS; HYDROGEN PEROXIDE; INTEGRASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SODIUM CHLORIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 46849106050     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800031k     Document Type: Article

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