Enhanced coexpression of thioredoxin and high mobility group protein 1 genes in human hepatocellular carcinoma and the possible association with decreased sensitivity to cisplatin

Cancer Research

Volumn 56, Issue 23, 1996, Pages 5330-5333

  Kawahara, Naoyuki ^a   Tanaka, Toshiya ^a   Yokomizo, Akira ^a   Nanri, Hiroki ^b   Ono, Mayumi ^a   Wada, Morimasa ^a   Kohno, Kimitoshi ^b   Takenaka, Kenji ^a   Sugimachi, Keizo ^a   Kuwano, Michihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DOXORUBICIN; GLUTATHIONE TRANSFERASE; HIGH MOBILITY GROUP PROTEIN; MESSENGER RNA; MITOMYCIN C; THIOREDOXIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CLINICAL ARTICLE; DRUG SENSITIVITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL;

ADULT; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CISPLATIN; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE TRANSFERASE; HIGH MOBILITY GROUP PROTEINS; HMGB1 PROTEIN; HUMANS; ISOENZYMES; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; MITOMYCIN; RNA, MESSENGER; RNA, NEOPLASM; THIOREDOXIN;

EID: 12644261425     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Yodoi, J., and Uchiyama, T. Diseases associated with HTLV-I: virus, IL-2 receptor deregulation and redox regulation. Immunol. Today, 13: 405-411, 1992.
2. Hayashi, T , Ueno, Y., and Okamoto, T. Oxidoreductive regulation of nuclear factor κB. J Biol. Chem., 268: 11380-11388, 1993.
3. Abate, C , Patel, L., Rauscher, F J., III, and Curran, T. Redox regulation of Fos and Jun DNA-binding activity in vitro. Science (Washington DC), 249: 1157-1161, 1990.
4. Holmgren, A. Thioredoxin and glutaredoxin systems. J Biol Chem , 264: 13963-13966, 1989
5. Nakamura, H , Matsuda, M , Furuke, K., Kitaoka, Y , Iwata, S , Toda, K., Inamoto, T , Yamaoka, Y , Ozawa, K , and Yodoi, J Adult T cell leukemia-derived factor/ human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol. Lett., 42: 75-80, 1994
6. Yokomizo, A , Ono, M., Nanri, H , Makino, Y , Ohga, T , Wada, M , Okamoto, T , Yodoi, J., Kuwano, M., and Kohno, K Cellular levels of TRX associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide Cancer Res., 55: 4293-4296, 1995.
7. Sasada, T , Iwata, S , Sato, N., Kitaoka, Y., Hirota, K , Nakamura, K., Nishiyama, A., Taniguchi, Y , Takabayashi, A., and Yodoi, J. Redox control of resistance to cis-diamminedichloroplatinum(II)(CDDP). J. Clin. Invest., 97: 2268-2276, 1996
8. Yokomizo, A., Kohno, K , Wada, M., Ono, M., Morrow, C., Cowan, K. H., and Kuwano, M. Markedly decreased expression of glutathione S-transferase π gene in human cancer cell lines resistant to buthionine sulfoximine, an inhibitor of cellular glutathione synthesis J. Biol. Chem , 270: 19451-19457, 1995.
9. Chu, G Cellular responses to cisplatin. J. Biol Chem., 269: 787-790, 1994.
10. Timmer-Bosscha, H., Mulder, N. H., and de Vries, E. G. Modulation of cis-diamminedichloroplatinum(II) resistance: a review Br J. Cancer, 66: 227-238, 1992.
11. Tew, K. D. Glutathione-associated enzymes in anticancer drug resistance Cancer Res., 54: 4313-4320, 1994.
12. Fraval, H. N., Rawlings, C J , and Roberts, J. J. Increased sensitivity of UV-repair-deficient human cells to DNA bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from Micrococcus luteus. Mutat. Res , 51: 121-132, 1978
13. Bustin, M., Lehn, D. A., and Landsman, D. Structural features of the HMG chromosomal proteins and their genes. Biochim. Biophy Acta, 1049 231-243, 1990
14. Pil, P. M., and Lippard, S. J. Specific binding of chromosomal protein HMG-1 to DNA damaged by the anticancer drug cisplatin. Science (Washington DC), 256: 234-237, 1992
15. Huang, J C , Zambie, D B , Reardon, J. T., Lippard, S. J., and Sancar, A. HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease. Proc. Natl. Acad Sci USA, 91 10394-10398, 1994
16. Kuchler, K , and Thorner, J Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci USA, 89: 2302-2306, 1992
17. Shepherd, F A., Evans, W K., Blackstein, M. E., Fine, S., Heathcote, J., Langer, B., Taylor, B., Habal, F , Kutas, G , and Pritchard, K. I Hepatic arterial infusion of mitoxantrone in the treatment of primary hepatocellular carcinoma J Clin Oncol., 5: 635-640, 1987
18. Falkson, G., Ryan, L. M., Johnson, L A , Simson, I. W., Coetzer, B. J., Carbone, P P , Creech, R. H., and Schutt, A J. A random phase II study of mitoxantrone and cisplatin in patients with hepatocellular carcinoma. An ECOG study Cancer (Phila.), 60. 2141-2145, 1987.
19. Samoto, K., Ikezaki, K., Ono, M., Shono, T., Kohno, K., Kuwano, M., and Fukui, M. Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors Cancer Res , 55: 1189-1193, 1995
20. Okuyama, T , Maehara, Y , Endo, K., Baba, H , Adachi, Y., Kuwano, M , and Sugimachi, K Expression of glutathione S transferase pi and sensitivity of human gastric cancer cells to cisplatin. Cancer (Phila.), 74: 1230-1236, 1994
21. Maehara, Y., Anai, H., Kusumoto, H , and Sugimachi, K. Poorly differentiated human gastric carcinoma is more sensitive to antitumor drugs than is well differentiated carcinoma. Eur. J. Surg. Oncol , 13: 203-206, 1987.
22. Kohnoe, S., Maehara, Y., Takahashi, I., Yoshida, M , Emi, Y., Kusumoto, T., and Sugimachi, K Use of the succinate dehydrogenase inhibition test in assessing the heat sensitivity of tumor cells Oncology, 50: 500-504, 1993.
23. Satoh, K., Kitahara, A., Soma, Y., Inaba, Y., Hatayama, I., and Sato, K Purification, induction, and distribution of placental glutathione transferase: a new marker enzyme for preneoplastic cells in rat chemical hepatocarcinogenesis. Proc. Natl. Acad Sci. USA, 82: 3964-3968, 1985.
24. Thorgeirsson, S. S , Huber, B. E , Sorrell, S , Fojo, A., Pastan, I., and Gottesman, M. M Expression of the multidrug-resistant gene in hepatocarcinogenesis and regenerating rat liver. Science (Washington DC), 236: 1120-1122, 1987
25. Nakamura, H., Masutani, H., Tagaya, Y., Yamauchi, A., Inamoto, T., Nanbu, Y., Fujii, S., Ozawa, K , and Yodoi. J Expression and growth-promoting effect of adult T-cell leukemia-derived factor A human thioredoxin homologue in hepatocellular carcinoma. Cancer (Phila.), 69: 2091-2097, 1992.
26. Hagen, T M., Huang, S., Curnutte, J , Fowler, P., Martinez, V., Wehr, C M , Ames, B N , and Chisari, F V Extensive oxidative DNA damage in hepatocytes of transgenic mice with ned to develop hepatocellular carcinoma. Proc Natl. Acad. Sci. USA, 91, 12808-12812, 1994.
27. Brown, S. J., Kellett, P J , and Lippard, S. J Ixr1, a yeast protein that binds to platinated DNA and confers sensitivity to cisplatin Science (Washington DC), 261: 603-605, 1993
28. Bruhn, S L , Pil, P. M., Essigmann, J. M., Housman, D. E , and Lippard, S J Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin. Proc Natl. Acad. Sci USA, 89: 2307-2311, 1992