Study on colon-specific 5-Fu pH-enzyme Di-dependent chitosan microspheres

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 7, 2008, Pages 963-968

  Zhao, Xiu Li ^a   Li, Ke Xin ^a   Zhao, Xiu Feng ^b   Pang, Da Hai ^a   Chen, Da Wei ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b MUDANJIANG MEDICAL UNIVERSITY   (China)

Author keywords

5 Fu; Colon specific drug delivery; Emulsification chemical cross linking; Microsphere

Indexed keywords

CHITOSAN; FLUOROURACIL; MICROSPHERE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; COLON; CONTROLLED STUDY; CROSS LINKING; DRUG BLOOD LEVEL; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; EMULSION; FEMALE; MALE; MICROENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; RAT; SMALL INTESTINE; STOMACH;

ANIMALS; CHITOSAN; COLON; DRUG DELIVERY SYSTEMS; FEMALE; FLUOROURACIL; HYDROGEN-ION CONCENTRATION; MALE; MICROSPHERES; PARTICLE SIZE; RATS; RATS, WISTAR; SOLUBILITY;

EID: 46749118002     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.963     Document Type: Article

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