Physiopathology and regulation of factor XIII

Thrombosis and Haemostasis

Volumn 86, Issue 1, 2001, Pages 57-65

  Ichinose, A ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Bleeding disorder; Cross linking; Molecular abnormality; Transglutaminase; Wound healing

Indexed keywords

BLOOD CLOTTING FACTOR 13B; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8A; MESSENGER RNA; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TETRAMER; TRANSCRIPTION FACTOR;

BLEEDING DISORDER; BLOOD CLOTTING FACTOR 13B DEFICIENCY; CELL TYPE; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CROSS LINKING; DISEASE ACTIVITY; DISEASE CLASSIFICATION; DNA FLANKING REGION; ENZYME ACTIVE SITE; ENZYME BLOOD LEVEL; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; EXON; EXPERIMENT; FRAMESHIFT MUTATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE INSERTION; GENETIC ANALYSIS; HEMOPHILIA A; HUMAN; MISSENSE MUTATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PLASMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; REGULATORY MECHANISM; RNA SPLICING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TRANSCRIPTION TERMINATION; WOUND HEALING;

EID: 0034924217     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616201     Document Type: Conference Paper

References (78)

1. Structure of transglutaminases
2. Biochemical, structural, and transglutaminase substrate properties of human loricrin, the major epidermal cornified cell envelope protein
3. Transglutaminase induction by various cell death and apoptosis pathways
4. Human factor XIII: Fibrinstabilizing factor
5. Amino acid sequence of the a subunit of human factor XIII
6. Amino acid sequence of the B subunit of human factor XIII, a protein composed of ten repetitive segments
7. Amino acid sequence of guinea pig liver transglutaminase from its cDNA sequence
8. Limulus hemocyte transglutaminase. cDNA cloning, amino acid sequence, and tissue localization
9. Complete amino acid sequence and homologies of human erythrocyte membrane protein band 4.2
10. Electron microscopy and hydrodynamic properties of factor XIII subunits
11. Three-dimensional structure of a transglutaminase: Human blood coagulation factor XIII
12. Structural evidence that the activation peptide is not released upon thrombin cleavage of factor XIII
13. Domain structure, stability and domain-domain interactions in recombinant factor XIII
14. Two non-proline cis peptide bonds may be important for factor XIII function
15. Interaction of the factor XIII activation peptide with alpha-thrombin: Crystal structure of its enzyme-substrate analog complex
16. Characterization of the gene for the a subunit of human factor XIII (plasma transglutaminase), a blood coagulation factor
17. Organization of the gene for human erythrocyte membrane protein 4.2: Structural similarities with the gene for the a subunit of factor XIII
18. Genomic structure of keratinocyte transglutaminase. Recruitment of new exon for modified function
19. Structure of the gene for human transglutaminase 1
20. Structure and organization of the human transglutaminase 1 gene
21. Structure and organization of the human transglutaminase 3 gene: Evolutionary relationship to the transglutaminase family
22. Organization and structure of the human tissue transglutaminase gene
23. Localization of the coagulation factor XIII A subunit gene (F13A) to chromosome bands 6p24-p25
24. The human tissue transglutaminase gene maps on chromosome 20q12 by in situ fluorescence hybridization
25. Localization of the human prostate transglutaminase (type IV) gene (TGM4) to chromosome 3p21.33-p22 by fluorescence in situ hybridization
26. Nucleotide sequence of the gene for the B subunit of human factor XIII
27. Localization of the coagulation factor XIII B subunit gene (F13B) to chromosome bands 1q31-32.1 and restriction fragment length polymorphism at the locus
28. Coagulation factor XIII B subunit is encoded by a gene linked to the regulator of complement activation (RCA) gene cluster in man
29. Human genes for the alpha and beta chains of complement C4b-binding protein are closely linked in a head-to-tail arrangement
30. Characterization of cDNA coding for human factor XIIIa
31. Localization of the gene for coagulation factor XIII a-chain to chromosome 6 and identification of sites of synthesis
32. Transcriptional regulation of cell type-specific expression of the TATA-less A subunit gene for human coagulation factor XIII
33. Keratinocyte transglutaminase promoter analysis. Identification of a functional response element
34. Isolation and characterization of the human tissue transglutaminase gene promoter
35. The proximal promoter of the human transglutaminase 3 gene. Stratified squamous epithelial-specific expression in cultured cells is mediated by binding of Sp1 and ets transcription factors to a proximal promoter element
36. Activation of the human transglutaminase 1 promoter in transgenic mice: Terminal differentiation-specific expression of the TGM1-lacZ transgene in keratinized stratified squamous epithelia
37. Subunit antigen and activity levels of blood coagulation factor XIII in healthy individuals. Relation to sex, age smoking, and hypertension
38. Biosynthesis of factor XIII B subunit by human hepatoma cell lines
39. Coagulation factor XIII A and B subunits in bone marrow and liver transplantation
40. Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma
41. Factor XIIIa-expressing dermal dendrocytes in AIDS-associated cutaneous Kaposi's sarcomas
42. Factor XIII-dependent generation of 5th complement component(C5)-derived monocyte chemotactic factor coinciding with plasma clotting
43. Monocyte chemotactic factor in rheumatoid arthritis synovial tissue. Probably a cross-linked derivative of S19 ribosomal protein
44. Differential behavior of coagulation factor XIII in patients with inflammatory bowel disease and in patients with giant cell arteritis
45. Recombinant factor XIII improves established experimental colitis in rats
46. Possible roles of transglutaminases in Alzheimer's disease
47. Transglutaminase cross-linking of the tau protein
48. The normal and abnormal genes of the A and B subunits in coagulation factor XIII
49. Primary structure of blood coagulation factor XIIIa (fibrinoligase, transglutaminase) from human placenta
50. Association of a common polymorphism in the factor XIII gene with myocardial infarction
51. The association between the Val34Leu polymorphism in the factor XIII gene and brain infarction
52. The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure
53. Val34Leu polymorphism of plasma factor XIII: Biochemistry and epidemiology in familial thrombophilia
54. Examining thrombin hydrolysis of the factor XIII activation peptide segment leads to a proposal for explaining the cardioprotective effects observed with the factor XIII V34L mutation
55. Maternal blood coagulation factor XIII is associated with the development of cytotrophoblastic shell
56. Studies of factor XIII antigen in congenital factor XIII deficiency. A tentative classification of the disease in two groups
57. A new family with congenital factor XIII deficiency showing a deficit of both subunit A and B. Type I factor XIII deficiency
58. A familial factor XIII subunit B deficiency
59. Clinical pharmacokinetics of a placenta-derived factor XIII concentrate in type I and type II factor XIII deficiency
60. Molecular and genetic mechanisms of factor XIII A subunit deficiency
61. Molecular approach to structure-function relationship of human coagulation factor XIII
62. Factor XIII deficiency
63. Identification of a large deletion, spanning exons 4 to 11 of the human factor XIIIA gene, in a factor XIII-deficient family
64. Mutations causing coagulation factor XIII subunit A deficiency: Characterization of the mutant proteins after expression in yeast
65. Molecular mechanisms of mutations in factor XIII A-subunit deficiency: In vitro expression in COS-cells demonstrates intracellular degradation of the mutant proteins
66. Molecular mechanisms of type II factor XIII deficiency: Novel Gly562-Arg mutation and C-terminal truncation of the A subunit cause factor XIII deficiency as characterized in a mammalian expression system
67. A novel Asn344 deletion in the core domain of coagulation factor XIII A subunit: Its effects on protein structure and function
68. Identification and characterization of two missense mutations causing factor XIIIA deficiency
69. Arg260-Cys mutation in severe factor XIII deficiency: Conformational change of the A subunit is predicted by molecular modelling and mechanics
70. Novel deletion and insertion mutations cause splicing defects, leading to severe reduction in mRNA levels of the A subunit in severe factor XIII deficiency
71. Molecular basis of inherited factor XIII deficiency: Identification of multiple mutations provides insights into protein function
72. Molecular mechanism of a mild phenotype in coagulation factor XIII (FXIII) deficiency: A splicing mutation permitting partial correct splicing of FXIII A-subunit mRNA
73. Two genetic defects in a patient with complete deficiency of the b-subunit for coagulation factor XIII
74. Molecular and cellular basis of deficiency of the B subunit for factor XIII secondary to a Cys430-Phe mutation in the seventh Sushi domain
75. Type I factor XIII deficiency is caused by a genetic defect of its B subunit: Insertion of triplet AAC in exon III leads to premature termination in the second Sushi domain
76. A founder effect is proposed for factor XIII B subunit deficiency caused by the insertion of triplet AAC in exon III encoding the second sushi domain
77. Truncated mutant B subunit for factor XIII causes its deficiency due to impaired intracellular transportation
78. Expression and release of the A and B subunits for human coagulation factor XIII in baby hamster kidney (BHK) cells