Cyclic stretch-induced nuclear localization of transcription factors results in increased nuclear targeting of plasmids in alveolar epithelial cells

Journal of Gene Medicine

Volumn 10, Issue 6, 2008, Pages 668-678

  Lam, Anna P ^a   Dean, David A ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Cyclic stretch; Electroporation; Gene therapy; Plasmid; Trafficking; Transcription factors

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEAR FACTOR I; PLASMID VECTOR; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2;

ARTICLE; CELL ASSAY; CELL MANIPULATION; CELL NUCLEUS; CELL SURFACE; CELL TRANSPORT; CONTROLLED STUDY; CYCLIC STRETCH; ELECTROPORATION; GENE EXPRESSION; GENE LOCATION; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL NUCLEUS; EPITHELIAL CELLS; GENE TARGETING; HUMANS; IN SITU HYBRIDIZATION; PLASMIDS; PULMONARY ALVEOLI; STRESS, MECHANICAL; TRANSCRIPTION FACTORS;

EID: 46649114159     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1187     Document Type: Article

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