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Volumn 27, Issue 2, 2008, Pages 128-137

Atopic Eczema and the Filaggrin Story

Author keywords

[No Author keywords available]

Indexed keywords

FILAGGRIN;

EID: 46649111732     PISSN: 10855629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sder.2008.04.001     Document Type: Article
Times cited : (72)

References (80)
  • 1
    • 2342591290 scopus 로고    scopus 로고
    • Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization. October 2003
    • Johansson S.G., Bieber T., Dahl R., et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization. October 2003. J Allergy Clin Immunol 113 (2004) 832-836
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 832-836
    • Johansson, S.G.1    Bieber, T.2    Dahl, R.3
  • 3
    • 0027192827 scopus 로고
    • Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sample
    • Schultz Larsen F. Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 28 (1993) 719-723
    • (1993) J Am Acad Dermatol , vol.28 , pp. 719-723
    • Schultz Larsen, F.1
  • 4
    • 0022528787 scopus 로고
    • Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample
    • Larsen F.S., Holm N.V., and Henningsen K. Atopic dermatitis. A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 15 (1986) 487-494
    • (1986) J Am Acad Dermatol , vol.15 , pp. 487-494
    • Larsen, F.S.1    Holm, N.V.2    Henningsen, K.3
  • 5
    • 36649007230 scopus 로고    scopus 로고
    • Importance of genetic factors in the etiology of atopic dermatitis: A twin study
    • Thomsen S.F., Ulrik C.S., Kyvik K.O., et al. Importance of genetic factors in the etiology of atopic dermatitis: A twin study. Allergy Asthma Proc 25 (2007) 535-539
    • (2007) Allergy Asthma Proc , vol.25 , pp. 535-539
    • Thomsen, S.F.1    Ulrik, C.S.2    Kyvik, K.O.3
  • 6
    • 1642401285 scopus 로고    scopus 로고
    • Risk factors in allergy/asthma
    • Kaiser H.B. Risk factors in allergy/asthma. Allergy Asthma Proc 25 (2004) 7-10
    • (2004) Allergy Asthma Proc , vol.25 , pp. 7-10
    • Kaiser, H.B.1
  • 7
    • 4944239419 scopus 로고    scopus 로고
    • Association of parental eczema, hayfever, and asthma with atopic dermatitis in infancy: Birth cohort study
    • Wadonda-Kabondo N., Sterne J.A., Golding J., et al. Association of parental eczema, hayfever, and asthma with atopic dermatitis in infancy: Birth cohort study. Arch Dis Child 89 (2004) 917-921
    • (2004) Arch Dis Child , vol.89 , pp. 917-921
    • Wadonda-Kabondo, N.1    Sterne, J.A.2    Golding, J.3
  • 8
    • 1442348320 scopus 로고    scopus 로고
    • Perinatal predictors of atopic dermatitis occurring in the first six months of life
    • Moore M.M., Rifas-Shiman S.L., Rich-Edwards J.W., et al. Perinatal predictors of atopic dermatitis occurring in the first six months of life. Pediatrics 113 (2004) 468-474
    • (2004) Pediatrics , vol.113 , pp. 468-474
    • Moore, M.M.1    Rifas-Shiman, S.L.2    Rich-Edwards, J.W.3
  • 9
    • 26644469842 scopus 로고    scopus 로고
    • Atopic dermatitis with increased severity along a line of Blaschko
    • Hladik F., Jurecka W., Hayek B., et al. Atopic dermatitis with increased severity along a line of Blaschko. J Am Acad Dermatol 53 5 suppl 1 (2005) S221-S224
    • (2005) J Am Acad Dermatol , vol.53 , Issue.5 SUPPL. 1
    • Hladik, F.1    Jurecka, W.2    Hayek, B.3
  • 10
    • 10244250341 scopus 로고    scopus 로고
    • The immunogenetics of asthma and eczema: A new focus on the epithelium
    • Cookson W. The immunogenetics of asthma and eczema: A new focus on the epithelium. Nat Rev Immunol 4 (2004) 978-988
    • (2004) Nat Rev Immunol , vol.4 , pp. 978-988
    • Cookson, W.1
  • 11
    • 13244284843 scopus 로고    scopus 로고
    • Large-scale DNA microarray analysis of atopic skin lesions shows overexpression of an epidermal differentiation gene cluster in the alternative pathway and lack of protective gene expression in the cornified envelope
    • Sugiura H., Ebise H., Tazawa T., et al. Large-scale DNA microarray analysis of atopic skin lesions shows overexpression of an epidermal differentiation gene cluster in the alternative pathway and lack of protective gene expression in the cornified envelope. Br J Dermatol 152 (2005) 146-149
    • (2005) Br J Dermatol , vol.152 , pp. 146-149
    • Sugiura, H.1    Ebise, H.2    Tazawa, T.3
  • 12
    • 33845806349 scopus 로고    scopus 로고
    • Altered penetration of polyethylene glycols into uninvolved skin of atopic dermatitis patients
    • Jakasa I., Verberk M.M., Esposito M., et al. Altered penetration of polyethylene glycols into uninvolved skin of atopic dermatitis patients. J Invest Dermatol 127 (2007) 129-134
    • (2007) J Invest Dermatol , vol.127 , pp. 129-134
    • Jakasa, I.1    Verberk, M.M.2    Esposito, M.3
  • 13
    • 33745056500 scopus 로고    scopus 로고
    • Percutaneous penetration of sodium lauryl sulphate is increased in uninvolved skin of patients with atopic dermatitis compared with control subjects
    • Jakasa I., de Jongh C.M., Verberk M.M., et al. Percutaneous penetration of sodium lauryl sulphate is increased in uninvolved skin of patients with atopic dermatitis compared with control subjects. Br J Dermatol 155 (2006) 104-109
    • (2006) Br J Dermatol , vol.155 , pp. 104-109
    • Jakasa, I.1    de Jongh, C.M.2    Verberk, M.M.3
  • 14
    • 33645399288 scopus 로고    scopus 로고
    • Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
    • Palmer C.N., Irvine A.D., Terron-Kwiatkowski A., et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 38 (2006) 441-446
    • (2006) Nat Genet , vol.38 , pp. 441-446
    • Palmer, C.N.1    Irvine, A.D.2    Terron-Kwiatkowski, A.3
  • 15
    • 33645130154 scopus 로고    scopus 로고
    • Mendelian disorders deserve more attention
    • Antonarakis S.E., and Beckmann J.S. Mendelian disorders deserve more attention. Nat Rev Genet 7 (2006) 277-282
    • (2006) Nat Rev Genet , vol.7 , pp. 277-282
    • Antonarakis, S.E.1    Beckmann, J.S.2
  • 16
    • 0029932799 scopus 로고    scopus 로고
    • Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21
    • Mischke D., Korge B.P., Marenholz I., et al. Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21. J Invest Dermatol 106 (1996) 989-992
    • (1996) J Invest Dermatol , vol.106 , pp. 989-992
    • Mischke, D.1    Korge, B.P.2    Marenholz, I.3
  • 17
    • 0034533621 scopus 로고    scopus 로고
    • Epithelial structural proteins of the skin and oral cavity: Function in health and disease
    • Presland R.B., and Dale B.A. Epithelial structural proteins of the skin and oral cavity: Function in health and disease. Crit Rev Oral Biol Med 11 (2000) 383-408
    • (2000) Crit Rev Oral Biol Med , vol.11 , pp. 383-408
    • Presland, R.B.1    Dale, B.A.2
  • 18
    • 42749086738 scopus 로고    scopus 로고
    • Filaggrin expression in oral, nasal, and esophageal mucosa
    • De Benedetto A., Qualia C.M., Baroody F.M., et al. Filaggrin expression in oral, nasal, and esophageal mucosa. J Invest Dermatol 128 (2008) 1594-1597
    • (2008) J Invest Dermatol , vol.128 , pp. 1594-1597
    • De Benedetto, A.1    Qualia, C.M.2    Baroody, F.M.3
  • 19
    • 42749094080 scopus 로고    scopus 로고
    • Filaggrin mutations, atopic eczema, hay fever, and asthma in children
    • Weidinger S., O'Sullivan M., Illig T., et al. Filaggrin mutations, atopic eczema, hay fever, and asthma in children. J Allergy Clin Immunol 121 (2008) 1203-1204
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 1203-1204
    • Weidinger, S.1    O'Sullivan, M.2    Illig, T.3
  • 20
    • 33845198733 scopus 로고    scopus 로고
    • Lack of filaggrin expression in the human bronchial mucosa
    • Ying S., Meng Q., Corrigan C.J., et al. Lack of filaggrin expression in the human bronchial mucosa. J Allergy Clin Immunol 118 (2006) 1386-1388
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 1386-1388
    • Ying, S.1    Meng, Q.2    Corrigan, C.J.3
  • 21
    • 0025851310 scopus 로고
    • Interaction of filaggrin with keratin filaments during advanced stages of normal human epidermal differentiation and in ichthyosis vulgaris
    • Manabe M., Sanchez M., Sun T.T., et al. Interaction of filaggrin with keratin filaments during advanced stages of normal human epidermal differentiation and in ichthyosis vulgaris. Differentiation 48 (1991) 43-50
    • (1991) Differentiation , vol.48 , pp. 43-50
    • Manabe, M.1    Sanchez, M.2    Sun, T.T.3
  • 22
    • 17144371855 scopus 로고    scopus 로고
    • The cornified envelope: a model of cell death in the skin
    • Candi E., Schmidt R., and Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 6 (2005) 328-340
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 328-340
    • Candi, E.1    Schmidt, R.2    Melino, G.3
  • 23
    • 1342325502 scopus 로고    scopus 로고
    • Moisturization and skin barrier function
    • Rawlings A.V., and Harding C.R. Moisturization and skin barrier function. Dermatol Ther 17 suppl 1 (2004) 43-48
    • (2004) Dermatol Ther , vol.17 , Issue.SUPPL. 1 , pp. 43-48
    • Rawlings, A.V.1    Harding, C.R.2
  • 24
    • 0027534206 scopus 로고
    • Profilaggrin is a major epidermal calcium-binding protein
    • Markova N.G., Marekov L.N., Chipev C.C., et al. Profilaggrin is a major epidermal calcium-binding protein. Mol Cell Biol 13 (1993) 613-625
    • (1993) Mol Cell Biol , vol.13 , pp. 613-625
    • Markova, N.G.1    Marekov, L.N.2    Chipev, C.C.3
  • 25
    • 33845775154 scopus 로고    scopus 로고
    • Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis
    • McLean W.H., and Hull P.R. Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis. J Invest Dermatol 127 (2007) 8-10
    • (2007) J Invest Dermatol , vol.127 , pp. 8-10
    • McLean, W.H.1    Hull, P.R.2
  • 26
    • 0025154931 scopus 로고
    • Organization, structure, and polymorphisms of the human profilaggrin gene
    • Gan S.Q., McBride O.W., Idler W.W., et al. Organization, structure, and polymorphisms of the human profilaggrin gene. Biochemistry 29 (1990) 9432-9440
    • (1990) Biochemistry , vol.29 , pp. 9432-9440
    • Gan, S.Q.1    McBride, O.W.2    Idler, W.W.3
  • 27
    • 4143141022 scopus 로고    scopus 로고
    • Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis
    • Presland R.B., Coulombe P.A., Eckert R.L., et al. Barrier function in transgenic mice overexpressing K16, involucrin, and filaggrin in the suprabasal epidermis. J Invest Dermatol 123 (2004) 603-606
    • (2004) J Invest Dermatol , vol.123 , pp. 603-606
    • Presland, R.B.1    Coulombe, P.A.2    Eckert, R.L.3
  • 28
    • 46649119445 scopus 로고    scopus 로고
    • Loss-of-function mutations in the filaggrin gene lead to reduced level of natural moisturizing factor in the stratum corneum
    • Feb 28 [Epub ahead of print]
    • Kezic S., Kemperman P.M., Koster E.S., et al. Loss-of-function mutations in the filaggrin gene lead to reduced level of natural moisturizing factor in the stratum corneum. J Invest Dermatol (2008) Feb 28 [Epub ahead of print]
    • (2008) J Invest Dermatol
    • Kezic, S.1    Kemperman, P.M.2    Koster, E.S.3
  • 29
    • 84965266470 scopus 로고
    • Clinical features of autosomal dominant and sex-linked ichthyosis in an English population
    • Wells R.S., and Kerr C.B. Clinical features of autosomal dominant and sex-linked ichthyosis in an English population. BMJ 1 (1966) 947-950
    • (1966) BMJ , vol.1 , pp. 947-950
    • Wells, R.S.1    Kerr, C.B.2
  • 30
    • 41549117117 scopus 로고    scopus 로고
    • Filaggrin null mutations and childhood atopic eczema: A population-based case-control study
    • Brown S.J., Relton C.L., Liao H., et al. Filaggrin null mutations and childhood atopic eczema: A population-based case-control study. J Allergy Clin Immunol 121 (2008) 940-946
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 940-946
    • Brown, S.J.1    Relton, C.L.2    Liao, H.3
  • 31
    • 0021987007 scopus 로고
    • Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules
    • Sybert V.P., Dale B.A., and Holbrook K.A. Ichthyosis vulgaris: Identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules. J Invest Dermatol 84 (1985) 191-194
    • (1985) J Invest Dermatol , vol.84 , pp. 191-194
    • Sybert, V.P.1    Dale, B.A.2    Holbrook, K.A.3
  • 32
    • 33644622891 scopus 로고    scopus 로고
    • Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
    • Smith F.J., Irvine A.D., Terron-Kwiatkowski A., et al. Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris. Nat Genet 38 (2006) 337-342
    • (2006) Nat Genet , vol.38 , pp. 337-342
    • Smith, F.J.1    Irvine, A.D.2    Terron-Kwiatkowski, A.3
  • 33
    • 0031837471 scopus 로고    scopus 로고
    • Reduced stability and bi-allelic, coequal expression of profilaggrin mRNA in keratinocytes cultured from subjects with ichthyosis vulgaris
    • Nirunsuksiri W., Zhang S.H., and Fleckman P. Reduced stability and bi-allelic, coequal expression of profilaggrin mRNA in keratinocytes cultured from subjects with ichthyosis vulgaris. J Invest Dermatol 110 (1998) 854-861
    • (1998) J Invest Dermatol , vol.110 , pp. 854-861
    • Nirunsuksiri, W.1    Zhang, S.H.2    Fleckman, P.3
  • 34
    • 0041888517 scopus 로고    scopus 로고
    • Mapping of the associated phenotype of an absent granular layer in ichthyosis vulgaris to the epidermal differentiation complex on chromosome 1
    • Compton J.G., DiGiovanna J.J., Johnston K.A., et al. Mapping of the associated phenotype of an absent granular layer in ichthyosis vulgaris to the epidermal differentiation complex on chromosome 1. Exp Dermatol 11 (2002) 518-526
    • (2002) Exp Dermatol , vol.11 , pp. 518-526
    • Compton, J.G.1    DiGiovanna, J.J.2    Johnston, K.A.3
  • 35
    • 0027058170 scopus 로고
    • Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus
    • Presland R.B., Haydock P.V., Fleckman P., et al. Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus. J Biol Chem 267 (1992) 23772-23781
    • (1992) J Biol Chem , vol.267 , pp. 23772-23781
    • Presland, R.B.1    Haydock, P.V.2    Fleckman, P.3
  • 36
    • 33746129175 scopus 로고    scopus 로고
    • Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis
    • Sandilands A., O'Regan G.M., Liao H., et al. Prevalent and rare mutations in the gene encoding filaggrin cause ichthyosis vulgaris and predispose individuals to atopic dermatitis. J Invest Dermatol 126 (2006) 1770-1775
    • (2006) J Invest Dermatol , vol.126 , pp. 1770-1775
    • Sandilands, A.1    O'Regan, G.M.2    Liao, H.3
  • 37
    • 34247578168 scopus 로고    scopus 로고
    • Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
    • Sandilands A., Terron-Kwiatkowski A., Hull P.R., et al. Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema. Nat Genet 39 (2007) 650-654
    • (2007) Nat Genet , vol.39 , pp. 650-654
    • Sandilands, A.1    Terron-Kwiatkowski, A.2    Hull, P.R.3
  • 38
    • 0029813505 scopus 로고    scopus 로고
    • Decreased expression of filaggrin in atopic skin
    • Seguchi T., Cui C.Y., Kusuda S., et al. Decreased expression of filaggrin in atopic skin. Arch Dermatol Res 288 (1996) 442-446
    • (1996) Arch Dermatol Res , vol.288 , pp. 442-446
    • Seguchi, T.1    Cui, C.Y.2    Kusuda, S.3
  • 39
    • 0035072326 scopus 로고    scopus 로고
    • Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
    • Cookson W.O., Ubhi B., Lawrence R., et al. Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet 27 (2001) 372-373
    • (2001) Nat Genet , vol.27 , pp. 372-373
    • Cookson, W.O.1    Ubhi, B.2    Lawrence, R.3
  • 40
    • 33745353511 scopus 로고    scopus 로고
    • Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
    • Weidinger S., Illig T., Baurecht H., et al. Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations. J Allergy Clin Immunol 118 (2006) 214-219
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 214-219
    • Weidinger, S.1    Illig, T.2    Baurecht, H.3
  • 41
    • 33749315429 scopus 로고    scopus 로고
    • Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march
    • Marenholz I., Nickel R., Ruschendorf F., et al. Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march. J Allergy Clin Immunol 118 (2006) 866-871
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 866-871
    • Marenholz, I.1    Nickel, R.2    Ruschendorf, F.3
  • 42
    • 33749862108 scopus 로고    scopus 로고
    • Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany
    • Ruether A., Stoll M., Schwarz T., et al. Filaggrin loss-of-function variant contributes to atopic dermatitis risk in the population of Northern Germany. Br J Dermatol 155 (2006) 1093-1094
    • (2006) Br J Dermatol , vol.155 , pp. 1093-1094
    • Ruether, A.1    Stoll, M.2    Schwarz, T.3
  • 43
    • 33847029992 scopus 로고    scopus 로고
    • Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood
    • Barker J.N., Palmer C.N., Zhao Y., et al. Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood. J Invest Dermatol 127 (2007) 564-567
    • (2007) J Invest Dermatol , vol.127 , pp. 564-567
    • Barker, J.N.1    Palmer, C.N.2    Zhao, Y.3
  • 44
    • 33847068830 scopus 로고    scopus 로고
    • Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis
    • Stemmler S., Parwez Q., Petrasch-Parwez E., et al. Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis. J Invest Dermatol 127 (2007) 722-724
    • (2007) J Invest Dermatol , vol.127 , pp. 722-724
    • Stemmler, S.1    Parwez, Q.2    Petrasch-Parwez, E.3
  • 45
    • 33847052500 scopus 로고    scopus 로고
    • Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis
    • Weidinger S., Rodriguez E., Stahl C., et al. Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis. J Invest Dermatol 127 (2007) 724-726
    • (2007) J Invest Dermatol , vol.127 , pp. 724-726
    • Weidinger, S.1    Rodriguez, E.2    Stahl, C.3
  • 46
    • 33847025339 scopus 로고    scopus 로고
    • Fleshing out filaggrin phenotypes
    • Irvine A.D. Fleshing out filaggrin phenotypes. J Invest Dermatol 127 (2007) 504-507
    • (2007) J Invest Dermatol , vol.127 , pp. 504-507
    • Irvine, A.D.1
  • 47
    • 34247579998 scopus 로고    scopus 로고
    • Filaggrin mutations in children with severe atopic dermatitis
    • Morar N., Cookson W.O., Harper J.I., et al. Filaggrin mutations in children with severe atopic dermatitis. J Invest Dermatol 127 (2007) 1667-1672
    • (2007) J Invest Dermatol , vol.127 , pp. 1667-1672
    • Morar, N.1    Cookson, W.O.2    Harper, J.I.3
  • 48
    • 43749107303 scopus 로고    scopus 로고
    • Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel
    • Novak N., Baurecht H., Schafer T., et al. Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel. J Invest Dermatol 128 (2008) 1430-1435
    • (2008) J Invest Dermatol , vol.128 , pp. 1430-1435
    • Novak, N.1    Baurecht, H.2    Schafer, T.3
  • 49
    • 36348995447 scopus 로고    scopus 로고
    • R501X and 2282del4 filaggrin mutations do not confer susceptibility to psoriasis and atopic dermatitis in Italian patients
    • Giardina E., Paolillo N., Sinibaldi C., et al. R501X and 2282del4 filaggrin mutations do not confer susceptibility to psoriasis and atopic dermatitis in Italian patients. Dermatology 216 (2008) 83-84
    • (2008) Dermatology , vol.216 , pp. 83-84
    • Giardina, E.1    Paolillo, N.2    Sinibaldi, C.3
  • 50
    • 38949177427 scopus 로고    scopus 로고
    • Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families
    • Ekelund E., Lieden A., Link J., et al. Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families. Acta Derm Venereol 88 (2008) 15-19
    • (2008) Acta Derm Venereol , vol.88 , pp. 15-19
    • Ekelund, E.1    Lieden, A.2    Link, J.3
  • 51
    • 41449089071 scopus 로고    scopus 로고
    • The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study
    • Henderson J., Northstone K., Lee S.P., et al. The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study. J Allergy Clin Immunol 121 (2008) 872-877
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 872-877
    • Henderson, J.1    Northstone, K.2    Lee, S.P.3
  • 52
    • 33846820433 scopus 로고    scopus 로고
    • Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis
    • Nomura T., Sandilands A., Akiyama M., et al. Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis. J Allergy Clin Immunol 119 (2007) 434-440
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 434-440
    • Nomura, T.1    Sandilands, A.2    Akiyama, M.3
  • 53
    • 33846280156 scopus 로고    scopus 로고
    • Filaggrin mutations p.R501X and c. 2282del4 in ichthyosis vulgaris
    • Gruber R., Janecke A.R., Fauth C., et al. Filaggrin mutations p.R501X and c. 2282del4 in ichthyosis vulgaris. Eur J Hum Genet 15 (2007) 179-184
    • (2007) Eur J Hum Genet , vol.15 , pp. 179-184
    • Gruber, R.1    Janecke, A.R.2    Fauth, C.3
  • 54
    • 42149190704 scopus 로고    scopus 로고
    • De novo occurrence of the filaggrin mutation p.r501x with prevalent mutation c. 3321delA in a Japanese Family with ichthyosis vulgaris complicated by atopic dermatitis
    • Hamada T., Sandilands A., Fukuda S., et al. De novo occurrence of the filaggrin mutation p.r501x with prevalent mutation c. 3321delA in a Japanese Family with ichthyosis vulgaris complicated by atopic dermatitis. J Invest Dermatol 128 (2008) 1323-1325
    • (2008) J Invest Dermatol , vol.128 , pp. 1323-1325
    • Hamada, T.1    Sandilands, A.2    Fukuda, S.3
  • 55
    • 43749087602 scopus 로고    scopus 로고
    • Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema
    • Brown S.J., Sandilands A., Zhao Y., et al. Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema. J Invest Dermatol 128 (2008) 1591-1594
    • (2008) J Invest Dermatol , vol.128 , pp. 1591-1594
    • Brown, S.J.1    Sandilands, A.2    Zhao, Y.3
  • 56
    • 43749114293 scopus 로고    scopus 로고
    • Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan
    • Nomura T., Akiyama M., Sandilands A., et al. Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan. J Invest Dermatol 128 (2008) 1436-1441
    • (2008) J Invest Dermatol , vol.128 , pp. 1436-1441
    • Nomura, T.1    Akiyama, M.2    Sandilands, A.3
  • 57
    • 44949200050 scopus 로고    scopus 로고
    • Unique and recurrent mutations in the filaggrin gene in Singaporean Chinese patients with ichthyosis vulgaris
    • Jan 31 [Epub ahead of print]
    • Chen H., Ho J.C., Sandilands A., et al. Unique and recurrent mutations in the filaggrin gene in Singaporean Chinese patients with ichthyosis vulgaris. J Invest Dermatol (2008) Jan 31 [Epub ahead of print]
    • (2008) J Invest Dermatol
    • Chen, H.1    Ho, J.C.2    Sandilands, A.3
  • 58
    • 36749006298 scopus 로고    scopus 로고
    • Toward a major risk factor for atopic eczema: Meta-analysis of filaggrin polymorphism data
    • Baurecht H., Irvine A.D., Novak N., et al. Toward a major risk factor for atopic eczema: Meta-analysis of filaggrin polymorphism data. J Allergy Clin Immunol 120 (2007) 1406-1412
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 1406-1412
    • Baurecht, H.1    Irvine, A.D.2    Novak, N.3
  • 60
    • 37749031114 scopus 로고    scopus 로고
    • Analysis of SPINK 5.KLK 7 and FLG genotypes in a French atopic dermatitis cohort
    • Hubiche T., Ged C., Benard A., et al. Analysis of SPINK 5.KLK 7 and FLG genotypes in a French atopic dermatitis cohort. Acta Derm Venereol 87 (2007) 499-505
    • (2007) Acta Derm Venereol , vol.87 , pp. 499-505
    • Hubiche, T.1    Ged, C.2    Benard, A.3
  • 61
    • 33645401909 scopus 로고    scopus 로고
    • Skin barrier function and allergic risk
    • Hudson T.J. Skin barrier function and allergic risk. Nat Genet 38 (2006) 399-400
    • (2006) Nat Genet , vol.38 , pp. 399-400
    • Hudson, T.J.1
  • 62
    • 33745524911 scopus 로고    scopus 로고
    • Breaking the (un)sound barrier: Filaggrin is a major gene for atopic dermatitis
    • Irvine A.D., and McLean W.H. Breaking the (un)sound barrier: Filaggrin is a major gene for atopic dermatitis. J Invest Dermatol 126 (2006) 1200-1202
    • (2006) J Invest Dermatol , vol.126 , pp. 1200-1202
    • Irvine, A.D.1    McLean, W.H.2
  • 63
    • 34250828434 scopus 로고    scopus 로고
    • Cytokine modulation of atopic dermatitis filaggrin skin expression
    • Howell M.D., Kim B.E., Gao P., et al. Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol 120 (2007) 150-155
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 150-155
    • Howell, M.D.1    Kim, B.E.2    Gao, P.3
  • 65
    • 34250797912 scopus 로고    scopus 로고
    • Filaggrin null mutations are associated with increased asthma severity in children and young adults
    • Palmer C.N., Ismail T., Lee S.P., et al. Filaggrin null mutations are associated with increased asthma severity in children and young adults. J Allergy Clin Immunol 120 (2007) 64-68
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 64-68
    • Palmer, C.N.1    Ismail, T.2    Lee, S.P.3
  • 66
    • 49249113869 scopus 로고    scopus 로고
    • Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults
    • Feb 23 [Epub ahead of print]
    • Basu K., Palmer C.N., Lipworth B.J., et al. Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults. Allergy (2008) Feb 23 [Epub ahead of print]
    • (2008) Allergy
    • Basu, K.1    Palmer, C.N.2    Lipworth, B.J.3
  • 67
    • 36148997706 scopus 로고    scopus 로고
    • Filaggrin null alleles are not associated with hand eczema or contact allergy
    • Lerbaek A., Bisgaard H., Agner T., et al. Filaggrin null alleles are not associated with hand eczema or contact allergy. Br J Dermatol 157 (2007) 1199-1204
    • (2007) Br J Dermatol , vol.157 , pp. 1199-1204
    • Lerbaek, A.1    Bisgaard, H.2    Agner, T.3
  • 68
    • 43749085744 scopus 로고    scopus 로고
    • Are filaggrin mutations associated with hand eczema or contact allergy?. We do not know
    • (letter)
    • Brown S.J., and Cordell H.J. Are filaggrin mutations associated with hand eczema or contact allergy?. We do not know. Br J Dermatol 158 (2008) 1383-1384 (letter)
    • (2008) Br J Dermatol , vol.158 , pp. 1383-1384
    • Brown, S.J.1    Cordell, H.J.2
  • 69
    • 1842422281 scopus 로고    scopus 로고
    • The genetics of psoriasis, psoriatic arthritis and atopic dermatitis
    • Bowcock A.M., and Cookson W.O. The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet 13 (2004) R43-R55
    • (2004) Hum Mol Genet , vol.13
    • Bowcock, A.M.1    Cookson, W.O.2
  • 70
    • 34447580008 scopus 로고    scopus 로고
    • Filaggrin null alleles are not associated with psoriasis
    • Zhao Y., Terron-Kwiatkowski A., Liao H., et al. Filaggrin null alleles are not associated with psoriasis. J Invest Dermatol 127 (2007) 1878-1882
    • (2007) J Invest Dermatol , vol.127 , pp. 1878-1882
    • Zhao, Y.1    Terron-Kwiatkowski, A.2    Liao, H.3
  • 71
    • 34248561298 scopus 로고    scopus 로고
    • Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort
    • Weichenthal M., Ruether A., Schreiber S., et al. Filaggrin R501X and 2282del4 mutations are not associated with chronic plaque-type psoriasis in a German cohort. J Invest Dermatol 127 (2007) 1535-1537
    • (2007) J Invest Dermatol , vol.127 , pp. 1535-1537
    • Weichenthal, M.1    Ruether, A.2    Schreiber, S.3
  • 72
    • 17744373329 scopus 로고    scopus 로고
    • Genetics of Crohn's disease, an archetypal inflammatory barrier disease
    • Schreiber S., Rosenstiel P., Albrecht M., et al. Genetics of Crohn's disease, an archetypal inflammatory barrier disease. Nat Rev Genet 6 (2005) 376-388
    • (2005) Nat Rev Genet , vol.6 , pp. 376-388
    • Schreiber, S.1    Rosenstiel, P.2    Albrecht, M.3
  • 74
    • 33748894922 scopus 로고    scopus 로고
    • Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history
    • Goh C., Finkel M., Christos P.J., and Sinha A.A. Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history. J Eur Acad Dermatol Venereol 20 (2006) 1055-1060
    • (2006) J Eur Acad Dermatol Venereol , vol.20 , pp. 1055-1060
    • Goh, C.1    Finkel, M.2    Christos, P.J.3    Sinha, A.A.4
  • 75
    • 34447529090 scopus 로고    scopus 로고
    • Filaggrin expression and the pathogenesis of epidermal cysts
    • Kurokawa I., Umeda K., Nishimura K., et al. Filaggrin expression and the pathogenesis of epidermal cysts. Br J Dermatol 157 (2007) 415-416
    • (2007) Br J Dermatol , vol.157 , pp. 415-416
    • Kurokawa, I.1    Umeda, K.2    Nishimura, K.3
  • 76
    • 0024208087 scopus 로고
    • Monoclonal antibody labeling for cytokeratins and filaggrin in the human pilosebaceous unit of normal, seborrheic and acne skin
    • Kurokawa I., Mayer-da-Silva A., Gollnick H., et al. Monoclonal antibody labeling for cytokeratins and filaggrin in the human pilosebaceous unit of normal, seborrheic and acne skin. J Invest Dermatol 91 (1988) 566-571
    • (1988) J Invest Dermatol , vol.91 , pp. 566-571
    • Kurokawa, I.1    Mayer-da-Silva, A.2    Gollnick, H.3
  • 77
    • 33947504914 scopus 로고    scopus 로고
    • Cytokeratin and filaggrin expression in nevus comedonicus
    • Kurokawa I., Nakai Y., Nishimura K., et al. Cytokeratin and filaggrin expression in nevus comedonicus. J Cutan Pathol 34 (2007) 338-341
    • (2007) J Cutan Pathol , vol.34 , pp. 338-341
    • Kurokawa, I.1    Nakai, Y.2    Nishimura, K.3
  • 78
    • 36248957531 scopus 로고    scopus 로고
    • Filaggrin mutations are genetic modifying factors exacerbating X-linked ichthyosis
    • Liao H., Waters A.J., Goudie D.R., et al. Filaggrin mutations are genetic modifying factors exacerbating X-linked ichthyosis. J Invest Dermatol 127 (2007) 2795-2798
    • (2007) J Invest Dermatol , vol.127 , pp. 2795-2798
    • Liao, H.1    Waters, A.J.2    Goudie, D.R.3
  • 79
    • 0021824115 scopus 로고
    • The prevalence of accentuated palmoplantar markings and keratosis pilaris in atopic dermatitis, autosomal dominant ichthyosis and control dermatological patients
    • Mevorah B., Marazzi A., and Frenk E. The prevalence of accentuated palmoplantar markings and keratosis pilaris in atopic dermatitis, autosomal dominant ichthyosis and control dermatological patients. Br J Dermatol 112 (1985) 679-685
    • (1985) Br J Dermatol , vol.112 , pp. 679-685
    • Mevorah, B.1    Marazzi, A.2    Frenk, E.3


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