Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers

Mutation Research - DNA Repair

Volumn 409, Issue 1, 1998, Pages 49-56

  Vreeswijk, Maaike P G ^a   Overkamp, Miep W J I ^a   Westland, Birgit E ^a   Van Hees Stuivenberg, Sandrine ^a   Vrieling, Harry ^a,b   Zdzienicka, Małgorzata Z ^a,b   Van Zeeland, Albert A ^a,b   Mullenders, Leon H F ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JA Cohen Institute Interuniversity Research Institute for Radiopathology and Radiation Protection   (Netherlands)

Author keywords

Cockayne's syndrome; Mutation; Repair; UV light; UV photolesion

Indexed keywords

PYRIMIDINE DIMER;

ANIMAL CELL; ARTICLE; COCKAYNE SYNDROME; DNA REPAIR; GENE MUTATION; HAMSTER; MUTAGENESIS; NONHUMAN; PHOTOTOXICITY; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

ANIMALS; BASE SEQUENCE; CELL SURVIVAL; CHO CELLS; COCKAYNE SYNDROME; CRICETINAE; DNA; DNA REPAIR; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENESIS; PYRIMIDINE DIMERS; RADIATION TOLERANCE; RNA; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

CRICETINAE; CRICETULUS GRISEUS; RODENTIA;

EID: 0031693551     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(98)00038-X     Document Type: Article

References (23)

1. Venema J., Mullenders L.H.F., Natarajan A.T., van Zeeland A.A., Mayne L.V. The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA. Proc. Natl. Acad. Sci. USA. 87:1990;4707-4711.
2. van Hoffen A., Natarajan A.T., Mayne L.V., van Zeeland A.A., Mullenders L.H.F., Venema J. Deficient repair of the transcribed strand of active genes in Cockayne's syndrome. Nucleic Acids Res. 21:1993;5890-5895.
3. Kantor G.J., Bastin S.A. Repair of some active genes in Cockayne syndrome cells is at the genome overall rate. Mutat. Res. 336:1995;223-233.
4. Lehmann A.R. Three complementation groups in Cockayne syndrome. Mutat. Res. 106:1982;347-356.
5. Henning K.A., Li L., Iyer N., Mc Daniel L., Reagon M.S., Legerski R., Schults R.A., Stefanini M., Lehmann A.R., Mayne L.V., Friedberg E.C. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell. 82:1995;555-564.
6. Troelstra C., Odijk H., de Wit J., Westerveld J.A., Thompson L.H., Bootsma D., Hoeijmakers J.H.J. Molecular cloning of the human DNA excision repair gene ERCC6. Mol. Cell. Biol. 10:1990;5806-5813.
7. Busch D., Greiner C., Lewis K., Ford R., Adair G., Thompson L. Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening. Mutagenesis. 4:1989;349-354.
8. Thompson L.H., Salazar E.P., Brookman K.W., Collins C.C., Stewart S.A., Busch D.B., Weber C.A. Recent progress with the DNA repair mutants of Chinese hamster ovary cells. J. Cell. Sci. Suppl. 6:1987;97-110.
9. Zdzienicka M.Z., van der Schans G.P., Westerveld A., van Zeeland A.A., Simons J.W.I.M. Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines. Mutat. Res. 193:1988;31-41.
10. Vrieling H., Venema J., van Rooyen M.L., Groen N.A., Zdzienicka M.Z., Simons J.W.I.M., Lohman P.H.M., van Zeeland A.A. DNA strand specificity for UV-induced mutations in mammalian cells. Mol. Cell. Biol. 9:1989;1277-1283.
11. Menichini P., Vrieling H., van Zeeland A.A. Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells. Mutat. Res. 251:1991;143-155.
12. Zhang L.H., Jenssen D. Site specific of N-methyl-N-nitrosourea-induced transition mutations in the hprt gene. Carcinogenesis. 12:1991;1903-1909.
13. van Oosterwijk M.F., Versteeg A., Filon R., van Zeeland A.A., Mullenders L.H.F. The sensitivity of Cockayne syndrome cells to DNA-damaging agents is not due to defective transcription-coupled repair of active genes. Mol. Cell. Biol. 16:1996;4436-4444.
14. Vreeswijk M.P.G., van Hoffen A., Westland B.E., Vrieling H., van Zeeland A.A., Mullenders L.H.F. Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells. J. Biol. Chem. 269:1994;31858-31863.
15. Feinberg A.P., Vogelstein B. A technique for radiolabelling restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13.
16. 32P-labelled single-stranded probes using linear PCR: application of the method for analysis of strand-specific DNA repair Mutat. Res. 315:1994;189-195.
17. Lommel L., Hanawalt P.C. The genetic defect in the Chinese hamster ovary cell mutant UV61 permits moderate selective repair of cyclobutane pyrimidine dimers in an expressed gene. Mutat. Res. 255:1991;183-191.
18. Thompson L.H., Mitchell D.L., Regan J.D., Bouffler S.D., Stewart S.A., Carrier W.L., Nairn R.S., Johnson R.T. CHO mutant UV61 removes (6-4) photoproducts but not cyclobutane dimers. Mutagenesis. 4:1989;140-146.
19. Vrieling H., Venema J., van Rooyen M.L., van Hoffen A., Menichini P., Zdzienicka M.Z., Simons J.W.I.M., Mullenders L.H.F., van Zeeland A.A. Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene. Nucleic Acids Res. 19:1991;2411-2415.
20. Vrieling H., Zhang L.-H., van Zeeland A.A., Zdzienicka M.Z. UV-induced hprt mutations in a UV-sensitive hamster cell line from complementation group 3 are biased towards the transcribed strand. Mutat. Res. 274:1992;147-155.
21. Parris C.N., Kraemer K.H. Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal. Proc. Natl. Acad. Sci. USA. 90:1993;7260-7264.
22. van der Horst G.T., van Steeg H., Berg R.J., van Gool A.J., de Wit J., Weeda G., Morreau H., Beems R.B., van Kreijl C.F., de Gruijl F.R., Bootsma D., Hoeijmakers J.H. Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell. 89:1997;425-435.
23. van Hoffen A., venema J., Meschini R., van zeeland A.A., Mullenders L.H.F. Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts. EMBO J. 14:1995;360-367.