Disease-modifying effects of glucosamine HCl involving regulation of metalloproteinases and chemokines activated by interleukin-1β in human primary synovial fibroblasts

Journal of Cellular Biochemistry

Volumn 104, Issue 1, 2008, Pages 38-50

  Lu, Hsien Tsung ^a   Liang, Yu Chih ^b   Sheu, Ming Thau ^b   Ho, Hsiu O ^b   Lin, Ya Ting ^b   Hsieh, Ming Shium ^a   Chen, Chien Ho ^b  

^a TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Glucosamine; Matrix metalloproteinases; Osteoarthritis; Synovial fibroblasts

Indexed keywords

CHEMOKINE; COLLAGENASE 3; GELATINASE A; GLUCOSAMINE; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MESSENGER RNA; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSCRIPTION FACTOR; MATRIX METALLOPROTEINASE;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME INHIBITION; ENZYME REGULATION; FIBROBLAST; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SYNOVIOCYTE; UPREGULATION; CARTILAGE; METABOLISM; OSTEOARTHRITIS; PATHOLOGY; PHYSIOLOGY; SYNOVIUM;

CARTILAGE; CHEMOKINES; FIBROBLASTS; GENE EXPRESSION REGULATION; GLUCOSAMINE; HUMANS; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASES; NF-KAPPA B; OSTEOARTHRITIS; RNA, MESSENGER; SYNOVIAL MEMBRANE;

EID: 46449118670     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21597     Document Type: Article

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