-
1
-
-
37549032051
-
Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain
-
Naudi A, Caro P, Jove M, Gomez J, Boada J, Ayala V, Portero-Otin M, Barja G, Pamplona R. Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain. Rejuvenation Res 2007;10:473-483.
-
(2007)
Rejuvenation Res
, vol.10
, pp. 473-483
-
-
Naudi, A.1
Caro, P.2
Jove, M.3
Gomez, J.4
Boada, J.5
Ayala, V.6
Portero-Otin, M.7
Barja, G.8
Pamplona, R.9
-
2
-
-
33745970444
-
Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins
-
Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R, Barja G. Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins. FASEB J 2006;20:1064-1073.
-
(2006)
FASEB J
, vol.20
, pp. 1064-1073
-
-
Sanz, A.1
Caro, P.2
Ayala, V.3
Portero-Otin, M.4
Pamplona, R.5
Barja, G.6
-
3
-
-
23844464540
-
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels, and increases hepatocyte MIF levels and stress resistance
-
Miller, RA, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock M. Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-1 and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 2005;4:119-125.
-
(2005)
Aging Cell
, vol.4
, pp. 119-125
-
-
Miller, R.A.1
Buehner, G.2
Chang, Y.3
Harper, J.M.4
Sigler, R.5
Smith-Wheelock, M.6
-
4
-
-
0028557442
-
Methionine restriction increases blood glutathione and longevity in F344 rats
-
Richie JP Jr, Leutzinger Y, Parthasarathy S, Malloy V, Orentreich N, Zimmerman JA. Methionine restriction increases blood glutathione and longevity in F344 rats. FASEB J 1994;8:1303-1307.
-
(1994)
FASEB J
, vol.8
, pp. 1303-1307
-
-
Richie Jr, J.P.1
Leutzinger, Y.2
Parthasarathy, S.3
Malloy, V.4
Orentreich, N.5
Zimmerman, J.A.6
-
5
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman ER. Protein oxidation and aging. Science 1992;257:1220-1224.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
7
-
-
0025887533
-
Senescence and the accumulation of abnormal proteins
-
Rosenberger RF. Senescence and the accumulation of abnormal proteins. Mutat Res 1991;256:255-262.
-
(1991)
Mutat Res
, vol.256
, pp. 255-262
-
-
Rosenberger, R.F.1
-
8
-
-
33646793360
-
Accumulation of altered proteins and aging: Causes and effects
-
Hipkiss AR. Accumulation of altered proteins and aging: causes and effects. Expt Gerontol 2006;41:464-473.
-
(2006)
Expt Gerontol
, vol.41
, pp. 464-473
-
-
Hipkiss, A.R.1
-
9
-
-
33847199335
-
eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans
-
Syntichaki P, Troulinaki K, Tavernarakis N. eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans. Nature 2007;445:922-926.
-
(2007)
Nature
, vol.445
, pp. 922-926
-
-
Syntichaki, P.1
Troulinaki, K.2
Tavernarakis, N.3
-
10
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen M, Taubert T, Crawford D, Libina N, Lee S-J, Kenyon C. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Ageing Cell 2007;6:95-110.
-
(2007)
Ageing Cell
, vol.6
, pp. 95-110
-
-
Hansen, M.1
Taubert, T.2
Crawford, D.3
Libina, N.4
Lee, S.-J.5
Kenyon, C.6
-
11
-
-
33846418352
-
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
-
Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, Lithgow GJ, Kapahi P. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Ageing Cell 2007;6:111-119.
-
(2007)
Ageing Cell
, vol.6
, pp. 111-119
-
-
Pan, K.Z.1
Palter, J.E.2
Rogers, A.N.3
Olsen, A.4
Chen, D.5
Lithgow, G.J.6
Kapahi, P.7
-
12
-
-
34347375071
-
On why decreasing protein synthesis can increase lifespan
-
Hipkiss AR. On why decreasing protein synthesis can increase lifespan. Mech Ageing Dev 2007;128:412-414.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 412-414
-
-
Hipkiss, A.R.1
-
14
-
-
33846504706
-
A "silent" polymorphism in the eMDR1 gene changes substrate specificity
-
Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, Gottesman MM. A "silent" polymorphism in the eMDR1 gene changes substrate specificity. Science 2007;315:525-528.
-
(2007)
Science
, vol.315
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
Sauna, Z.E.4
Calcagno, A.M.5
Ambudkar, S.V.6
Gottesman, M.M.7
-
15
-
-
0035035637
-
Health span and life span in transgenic mice with modulated DNA repair
-
Walter CA, Zhou ZQ, Manquino D, Ikeno Y, Reddick R, Nelson J, Intano G, Herbert DC, McMahan CA, Hanes M. Health span and life span in transgenic mice with modulated DNA repair. Ann NY Acad Sci 2001;928:132-140.
-
(2001)
Ann NY Acad Sci
, vol.928
, pp. 132-140
-
-
Walter, C.A.1
Zhou, Z.Q.2
Manquino, D.3
Ikeno, Y.4
Reddick, R.5
Nelson, J.6
Intano, G.7
Herbert, D.C.8
McMahan, C.A.9
Hanes, M.10
-
16
-
-
33845918167
-
Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain
-
Zhu JX, Doyle HA, Mamula MJ, Aswad DW. Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain. J Biol Chem 2006;281:33802-33813.
-
(2006)
J Biol Chem
, vol.281
, pp. 33802-33813
-
-
Zhu, J.X.1
Doyle, H.A.2
Mamula, M.J.3
Aswad, D.W.4
-
17
-
-
33847355083
-
The L-isoaspartyl-O- methyltransferase in Caenorhabditis elegans larval longevity and autophagy
-
Gomez TA, Banfield KL, Trogler DM, Clarke SG. The L-isoaspartyl-O- methyltransferase in Caenorhabditis elegans larval longevity and autophagy. Devel Biol 2007;303:493-500.
-
(2007)
Devel Biol
, vol.303
, pp. 493-500
-
-
Gomez, T.A.1
Banfield, K.L.2
Trogler, D.M.3
Clarke, S.G.4
-
19
-
-
33744972513
-
Mitochondrial protein oxidation and degradation in response to oxidative tress and aging
-
Bulteau AL, Szweda LI, Friguet B. Mitochondrial protein oxidation and degradation in response to oxidative tress and aging. Exp Geront 2006;41;653-657.
-
(2006)
Exp Geront
, vol.41
, pp. 653-657
-
-
Bulteau, A.L.1
Szweda, L.I.2
Friguet, B.3
-
21
-
-
33847652900
-
Autophagy and neurodegeneration: When the cleaning crew goes on strike
-
Martinez-Vincente M, Cuevo AM. Autophagy and neurodegeneration: when the cleaning crew goes on strike. Lancet Neurol 2007;6:352-362.
-
(2007)
Lancet Neurol
, vol.6
, pp. 352-362
-
-
Martinez-Vincente, M.1
Cuevo, A.M.2
-
22
-
-
36549006049
-
Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging
-
Ngo JK, Davies KJ. Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging. Ann NY Acad Sci 2007;1119:78-87.
-
(2007)
Ann NY Acad Sci
, vol.1119
, pp. 78-87
-
-
Ngo, J.K.1
Davies, K.J.2
-
23
-
-
0003097634
-
Protein degradation in mitochondria: Implications for oxidative stress, aging and disease: a novel etiological classification of mitochondrial proteolytic disorders
-
Bota DA, Davies KJA. Protein degradation in mitochondria: implications for oxidative stress, aging and disease: a novel etiological classification of mitochondrial proteolytic disorders. Mitochondrion 2001;1:33-49.
-
(2001)
Mitochondrion
, vol.1
, pp. 33-49
-
-
Bota, D.A.1
Davies, K.J.A.2
-
24
-
-
17644425569
-
Somatostatin regulates brain amyloid-β peptide Aβ42 through modulation of proteolytic degradation
-
Saito T, Iwata N, Tsubuki S, Takaki Y, Takano J, Huang SM, Suemoto, T, Higuchi M, Saido TC. Somatostatin regulates brain amyloid-β peptide Aβ42 through modulation of proteolytic degradation. Nature Med 2005;11:434-439.
-
(2005)
Nature Med
, vol.11
, pp. 434-439
-
-
Saito, T.1
Iwata, N.2
Tsubuki, S.3
Takaki, Y.4
Takano, J.5
Huang, S.M.6
Suemoto, T.7
Higuchi, M.8
Saido, T.C.9
-
25
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: Review and hypothesis
-
Qiu WQ, Folstein MF. Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis. Neurobiol Aging 2006;27:190-198.
-
(2006)
Neurobiol Aging
, vol.27
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
26
-
-
35748935851
-
The mitochondrial protease HtrA2 is regulated by Parkinson's disease associated kinase PINK1
-
Plun-Favreau H, Klupsh K, Moisoi N, Gandi SG, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J. The mitochondrial protease HtrA2 is regulated by Parkinson's disease associated kinase PINK1. Nature Cell Biol 2007;9:1243-1252.
-
(2007)
Nature Cell Biol
, vol.9
, pp. 1243-1252
-
-
Plun-Favreau, H.1
Klupsh, K.2
Moisoi, N.3
Gandi, S.G.4
Kjaer, S.5
Frith, D.6
Harvey, K.7
Deas, E.8
Harvey, R.J.9
McDonald, N.10
Wood, N.W.11
Martins, L.M.12
Downward, J.13
-
27
-
-
0036144830
-
Erythromycin slows aging of Saccharomyces cerevisiae
-
Holbrook MA, Menninger JR. Erythromycin slows aging of Saccharomyces cerevisiae. J Gerontol Biol Sci 2002;57A:B29-B36.
-
(2002)
J Gerontol Biol Sci
, vol.57 A
-
-
Holbrook, M.A.1
Menninger, J.R.2
-
28
-
-
0036236006
-
The mitochondrian-lysosomal axis theory of aging: Accumulation of damages mitochondria as a result of imperfect autophagocytosis
-
Brunk UT, Terman A. The mitochondrian-lysosomal axis theory of aging: accumulation of damages mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 2002;269:1996-2002.
-
(2002)
Eur J Biochem
, vol.269
, pp. 1996-2002
-
-
Brunk, U.T.1
Terman, A.2
-
29
-
-
36749081539
-
mTOR controls mitochondrial oxidative function through a YY1-PGC-1[alpha] transcription complex
-
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1[alpha] transcription complex. Nature 2007;450:736-740.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
30
-
-
0034705167
-
Proteins are oxidatively carbonylated in response to reduced transcriptional and translation fidelity
-
Dunkan S, Farewell A, Ballesteros M, Taddei F, Nystrom T. Proteins are oxidatively carbonylated in response to reduced transcriptional and translation fidelity. Proc Natl Acad Sci USA 2000;97:5746-5749.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5746-5749
-
-
Dunkan, S.1
Farewell, A.2
Ballesteros, M.3
Taddei, F.4
Nystrom, T.5
-
31
-
-
0035903569
-
Bacterial senescence: Protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes
-
Ballesteros M, Fredriksson A, Henriksson J, Nystrom T. Bacterial senescence: protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes. EMBO J 2001;18:5280-5289.
-
(2001)
EMBO J
, vol.18
, pp. 5280-5289
-
-
Ballesteros, M.1
Fredriksson, A.2
Henriksson, J.3
Nystrom, T.4
-
32
-
-
34147125783
-
-
S upon carbon starvation. Genes Dev 2007;21:862-874.
-
S upon carbon starvation. Genes Dev 2007;21:862-874.
-
-
-
-
33
-
-
33748288063
-
Induction of reactive oxygen species and cell survival in the presence of advanced glycation end products and similar structures
-
Schmitt A, Bigl K, Meiners I, Schmitt J. Induction of reactive oxygen species and cell survival in the presence of advanced glycation end products and similar structures. Biochim Biophys Acta 2006;1763:927-936.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 927-936
-
-
Schmitt, A.1
Bigl, K.2
Meiners, I.3
Schmitt, J.4
-
35
-
-
33745478477
-
Potential roles for ubiquitin and the proteasome during ribosome biogenesis
-
Stavreva DA, Kawasaki M, Dundr M, Koberna K, Muller WG, Tsujimura-Takahashi T, Komatsu W, Hayano T, Isobe T, Raska I, Misteli T, Takahashi N, McNally JG. Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol 2006;26:5131-5145.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5131-5145
-
-
Stavreva, D.A.1
Kawasaki, M.2
Dundr, M.3
Koberna, K.4
Muller, W.G.5
Tsujimura-Takahashi, T.6
Komatsu, W.7
Hayano, T.8
Isobe, T.9
Raska, I.10
Misteli, T.11
Takahashi, N.12
McNally, J.G.13
-
36
-
-
33845610586
-
Interplay between protein synthesis and degradation in the CNS: Physiological and pathological implications
-
Ding Q, Cecarini V, Keller JN. Interplay between protein synthesis and degradation in the CNS: physiological and pathological implications. Trends Neurosci 2007;30:31-36.
-
(2007)
Trends Neurosci
, vol.30
, pp. 31-36
-
-
Ding, Q.1
Cecarini, V.2
Keller, J.N.3
-
37
-
-
33745977756
-
Proteasome inhibition induces reversible impairments in protein synthesis
-
Ding Q, Dimayuga E, Markesbury WR, Keller JN. Proteasome inhibition induces reversible impairments in protein synthesis. FASEB J 2006;20:1055-1063.
-
(2006)
FASEB J
, vol.20
, pp. 1055-1063
-
-
Ding, Q.1
Dimayuga, E.2
Markesbury, W.R.3
Keller, J.N.4
-
38
-
-
0038740639
-
Do developmentally-related changes in constitutive proteolysis affect aberrant protein accumulation and generation of the aged phenotype?
-
Hipkiss AR. Do developmentally-related changes in constitutive proteolysis affect aberrant protein accumulation and generation of the aged phenotype? Mech Ageing Dev 2003;124:575-579.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 575-579
-
-
Hipkiss, A.R.1
|