Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products

Journal of Biological Chemistry

Volumn 279, Issue 39, 2004, Pages 41149-41156

  Jansson, Anna ^a   Koskiniemi, Hanna ^b   Mäntsälä, Pekka ^b   Niemi, Jarmo ^b   Schneider, Gunter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; ENZYMES; MUTAGENESIS;

CATALYTIC CYCLE; ENTROPIC ENZYME; LIGAND; TERNARY COMPLEX;

CRYSTAL STRUCTURE;

DAUNORUBICIN; METHYLTRANSFERASE; PROTEIN DNRK; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL METABOLISM; CATALYSIS; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES PEUCETIUS;

AMINO ACID SEQUENCE; ANTIBIOTICS, ANTINEOPLASTIC; BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; DAUNORUBICIN; DIMERIZATION; ELECTRONS; HISTIDINE; LIGANDS; METHYLATION; METHYLTRANSFERASES; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SOFTWARE; STREPTOMYCES;

BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES PEUCETIUS;

EID: 4644371272     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407081200     Document Type: Article

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