Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine

Proteins: Structure, Function and Genetics

Volumn 45, Issue 4, 2001, Pages 397-407

  Lim, Kap ^a   Zhang, Hong ^a   Tempczyk, Aleksandra ^a   Bonander, Nicklas ^a,b   Toedt, John ^a,b   Howard, Andrew ^c,d   Eisenstein, Edward ^a,b   Herzberg, Osnat ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

E.C. 2.1.1; Haemophilus influenzae; Methyltransferases; Structural genomics; YecO

Indexed keywords

ANION; ARGININE; BENZOIC ACID DERIVATIVE; CHLORIDE ION; METHYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; SOLVENT; SULFUR;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENOME; HAEMOPHILUS INFLUENZAE; HYDROPHOBICITY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FOLDING;

BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HAEMOPHILUS INFLUENZAE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN METHYLTRANSFERASES; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLHOMOCYSTEINE; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

HAEMOPHILUS INFLUENZAE;

EID: 0035576364     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10004     Document Type: Article

References (32)

1. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. Preparation of selenomethionyl proteins for phase determination
4. Data processing in macromolecular crystallography
5. Processing of X-ray diffraction data collected in oscillation mode
6. Automated structure solution for MIR and MAD
7. SHELX: Applications to macromolecules
8. The CCP4 suite programs for protein crystallography
9. Maximum likelihood refinement of heavy atom parameters
10. DM: An automated procedure for phase improvement of density modification
11. Automated protein model building combined with iterative structure refinement
12. Improved methods for building protein models in electron density maps and the location of errors in these models
13. Crystallography and NMR system: A new software suite for macromolecular structure determination
14. Databases in protein crystallography
15. PROCHECK: A program to check the stereochemical quality of protein structures
16. Analytical molecular surface calculation
17. A program to produce both detailed and schematic plots of protein structures
18. A fast algorithm for rendering spacefilling molecule pictures
19. Raster3D: Photorealistic molecular graphics
20. Crystal structure of the DpnM DNA adenine methyltransferase from the DpnII restriction system of Streptococcus pneumoniae bound to S-adenosylmethionine
21. Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-adenosylmethionine
22. Protein structure comparison by alignment of distance matrices
23. Surprising similarities in structure comparison
24. Crystal structure of glycine N-methyltransferase from rat liver
25. Crystal structure of catechol O-methyltransferase
26. Kinetics and mechanism of methyl transfer from sulfonium compounds to various nucleophiles
27. On the mechanism of the reaction catalyzed by thymidylate synthetase
28. Modeling of reaction steps relevant to deoxyuridylate (dUMP) enzymatic methylation and thymidylate synthase mechanism-based inhibition
29. Elicitor induction of S-adenosyl-L-methionine-anthranilic acid N-methyltransferase activity in cell-suspension and organ-cultures of Ruta graveolens L
30. Biosynthesis of trigonelline
31. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice