Mechanisms underlying intestinal injury induced by anti-inflammatory COX inhibitors

European Journal of Pharmacology

Volumn 500, Issue 1-3 SPEC. ISS., 2004, Pages 427-439

  Whittle, Brendan J R ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

COX (Cyclo oxygenase); COX 2 inhibitor; Coxib; Enteral bacteria; Enteropathy; INOS; Intestinal permeability; Neutrophil; Nitric oxide; NSAID; Peroxynitrite

Indexed keywords

ACETYLSALICYLIC ACID; AMPICILLIN; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; BACITRACIN; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; DICLOFENAC DERIVATIVE; ENDOTOXIN; FLURBIPROFEN; IBUPROFEN; INDOMETACIN; METRONIDAZOLE; NABUMETONE; NAPROXEN; NEOMYCIN; NITRIC OXIDE SYNTHASE; NITROFENAC; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN; PEROXYNITRITE; POLYMYXIN B; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; SUPEROXIDE; UNCLASSIFIED DRUG;

BACTERIUM; BLEEDING; CELL INFILTRATION; CELL MEMBRANE PERMEABILITY; CHEMICAL INTERACTION; DUODENUM MUCOSA; ENTERITIS; ENTEROHEPATIC CIRCULATION; ENTEROPATHY; EPITHELIUM; HUMAN; INCIDENCE; INFLAMMATION; INTESTINE INJURY; MICROVASCULATURE; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN DEPLETION; REVIEW; SMALL INTESTINE; STOMACH MUCOSA; ULCER; UPPER GASTROINTESTINAL TRACT;

ANIMALS; CYCLOOXYGENASE INHIBITORS; GASTROINTESTINAL DISEASES; HUMANS; ULCER;

EID: 4644356963     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.07.042     Document Type: Review

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