Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats

Journal of Physiology and Pharmacology

Volumn 50, Issue 1, 1999, Pages 25-38

  Konaka, A ^a   Nishijima, M ^a   Tanaka, A ^a   Kunikata, T ^a   Kato, S ^a   Takeuchi, K ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Indomethacin; Inducible NO synthase (iNOS); Intestinal lesions; Mast cells; Nitric oxide (NO)

Indexed keywords

1 [7 (4 FLUOROPHENYL) 1,2,3,4 TETRAHYDRO 8 (4 PYRIDYL)PYRAZOLO[5,1 C][1,2,4]TRIAZIN 2 YL] 2 PHENYLETHANEDIONE; 16,16 DIMETHYLPROSTAGLANDIN E2; 5 (2 HYDROXYPROPOXY) 4 OXO 8 PROPYL 4H 1 BENZOPYRAN 2 CARBOXYLIC ACID; ALLOPURINOL; AMINOGUANIDINE; CROMOGLYCATE DISODIUM; DEXAMETHASONE; HYDROXYUREA; IMMUNOMODULATING AGENT; INDOMETACIN; LINAZOLAST; METHYSERGIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; TRIPELENNAMINE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; INTESTINE INJURY; INTESTINE MUCOSA; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; MALE; NONHUMAN; PATHOGENESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GUANIDINES; INDOMETHACIN; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MAST CELLS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDES; TIME FACTORS;

EID: 0032962224     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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