Enhanced responses of glycosylphosphatidylinositol anchor-deficient T lymphocytes

Journal of Immunology

Volumn 173, Issue 6, 2004, Pages 3810-3815

  Hazenbos, Wouter L W ^a,d   Murakami, Yoshiko ^a   Nishimura, Jun Ichi ^b   Takeda, Junji ^c   Kinoshita, Taroh ^a  

^a OSAKA UNIVERSITY   (Japan)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CONCANAVALIN A; GLYCOSYLPHOSPHATIDYLINOSITOL; OVALBUMIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; LEUKOCYTE ADHERENCE; LYMPH NODE CELL; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

EID: 4644307472     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.6.3810     Document Type: Article

References (38)

1. Takeda, J., T. Miyata, K. Kawagoe, Y. Iida, Y. Endo, T. Fujita, M. Takahashi, T. Kitani, and T. Kinoshita. 1993. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobulinuria. Cell 73:703.
2. Kinoshita, T., N. Inoue, and J. Takeda. 1996. Role of phosphatidylinositol-linked proteins in paroxysmal nocturnal hemoglobulinuria pathogenesis. Annu. Rev. Med. 47:1.
3. Miyata, T., J. Takeda, Y. Iida, N. Yamada, N. Inoue, M. Takahashi, K. Maeda, T. Kitani, and T. Kinoshita. 1993. The cloning of PIG-A, a component in the early step of GPI-anchor synthesis. Science 259:1318.
4. Robinson, P. J., M. Millrain, J. Antoniou, E. Simpson, and A. L. Mellor. 1989. A glycophospholipid anchor is required for Qa-2-mediated T cell activation. Nature 342:85.
5. Brown, D. 1993. The tyrosine kinase connection: how GPI-anchored proteins activate T cells. Curr. Opin. Immunol. 5:349.
6. Malek, T. R., T. J. Fleming, and E. K. Codias. 1994. Regulation of T lymphocyte function by glycosylphosphatidylinositol (GPI)-anchored proteins. Semin. Immunol. 6:105.
7. Loertscher, R., and P. Lavery. 2002. The role of glycosyl phosphatidyl inositol (GPI)-anchored cell surface proteins in T-cell activation. Transpl. Immunol. 9:93.
8. + T cell activation. Proc. Natl. Acad. Sci. USA 96:1019.
9. Beissert, S., H.-T. He, A. O. Hueber, A. C. Lellouch, D. Metze, A. Mehling, T. A. Luger, T. Schwarz, and S. Grabbe. 1998. Impaired cutaneous immune responses in Thy-1-deficient mice. J. Immunol. 161:5296.
10. Marmor, M. D., M. F. Bachmann, P. S. Ohashi, T. R. Malek, and M. Julius. 1999. Immobilization of glycosylphosphatidylinositol-anchored proteins inhibits T cell growth but not function. Int. Immunol. 11:1381.
11. Stanford, W. L., S. Haque, R. Alexander, X. Liu, A. M. Latour, H. R. Snodgrass, B. H. Koller, and P. M. Flood. 1997. Altered proliferative response by T lymphocytes of Ly6A (Sca-1) null mice. J. Exp. Med. 29:705.
12. -/- mice show augmented TCR signaling and impaired differentiation. Curr. Biol. 7:705.
13. Takahama, Y., K. Ohishi, Y. Tokoro, T. Sugawara, Y. Yoshimura, M. Okabe, T. Kinoshita, and J. Takeda. 1998. Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene. Eur. J. Immunol. 28:2159.
14. Rajewsky, K., H. Gu, R. Kühn, U.A.K. Betz, W. Müller, J. Roes, and F. Schwenk. 1996. Conditional gene targeting. J. Clin. Invest. 98:600.
15. Tarutani, M., S. Itami, M. Okabe, M. Ikawa, T. Tezuka, K. Yoshikawa, T. Kinoshita, and J. Takeda. 1997. Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development. Proc. Natl. Acad. Sci. USA 94:7400.
16. Sprent, J., M. Schaefer, D. Lo, and R. Korngold. 1986. Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences. J. Exp. Med. 163:998.
17. Baiu, D. C., J. Prechl, A. Tchorbanov, H. D. Molina, A. Erdei, A. Sulica, P. J. A. Capel, and W. L. W. Hazenbos. 1999. Modulation of the humoral immune response by antibody-mediated antigen targeting to complement- and Fc receptors. J. Immunol. 162:3125.
18. Fitch, F. W., and T. F. Gajewski. 1997. Production of T cell clones. Curr. Prot. Immunol. 13.3.1.
19. Hawley, R. G., T. S. Hawley, A. Z. C. Fong, C. Quinto, M. Collins, J. P. Leonard, and S. J. Goldman. 1996. Thrombopoietic potential and serial repopulating ability of murine hematopoietic stem cells constitutively expressing interleukin 11. Proc. Natl. Acad. Sci. USA 93:10297.
20. Nishimura, J., K. L. Phillips, R. E. Ware, S. Hall, L. Wilson, T. L. Gentry, T. A. Howard, Y. Murakami, M. Shibano, T. Machii, et al. 2001. Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype. Blood 97:3004.
21. Bessler, M., V. Rosti, Y. Peng, G. Cattoretti, R. Notaro, S. Ohsako, K. B. Elkon, and L. Luzzatto. 2002. Glycosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Eur. J. Immunol. 32:2607.
22. Sugiyama, E., R. DeGasper, M. Urakaze, H.-M. Chang, L. J. Thomas, R. Hyman, C. D. Warren, and E. T. H. Yeh. 1991. Identification of defects in glycosylphosphatidylinositol anchor biosynthesis in the Thy-I expression mutants. J. Biol. Chem. 266:12119.
23. Weiss, A., R. Shields, M. Newton, B. Manger, and J. Imboden. 1987. Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene. J. Immunol. 138:2169.
24. Vidugiriene, J., and A. K. Menon. 1994. The GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum. J. Cell Biol. 127:333.
25. Naderer, T., and M. J. McConville. 2002. Characterization of a Leishmania mexicana mutant defective in synthesis of free and protein-linked GPI glycolipids. Mol. Biochem. Parasitol. 125:147.
26. Bryce, R. A., I. H. Hillier, and J. H. Naismith. 2001. Carbohydrate-protein recognition: molecular dynamics simulations and free energy analysis of oligosaccharide binding to concanavalin A. Biophys. J. 81:1373.
27. Green, E. D., and J. U. Baenziger. 1987. Oligosaccharide specificities of Phaseolus vulgaris leukoagglutinating and erythroagglutinating phytohemagglutinins. Interactions with N-glycanase-released oligosaccharides. J. Biol. Chem. 262:12018.
28. Schubert, J., P. Uciechowski, M. Zielinska-Skowronek, C. Tietjen, R. Leo, and R. E. Schmidt. 1992. Differences in activation of normal and glycosylphosphatidylinositol-negative lymphocytes derived from patients with paroxysmal nocturnal hemoglobinuria. J. Immunol. 148:3814.
29. Inoue, N., Y. Murakami, and T. Kinoshita. 2003. Molecular genetics of paroxysmal nocturnal hemoglobinuria. Int. J. Hematol. 77:107.
30. Murakami, Y., T. Kinoshita, Y. Maeda, T. Nakano, H. Kosaka, and J. Takeda. 1999. Different roles of glycosylphosphatidylinositol in various hematopoietic cells as revealed by a mouse model of paroxysmal nocturnal hemoglobinuria. Blood 94:2963.
31. Volarevic, S. A., C. M. Burns, J. J. Sussman, and J. D. Ashwell. 1990. Intimate association of Thy-1 and the T-cell antigen receptor with the CD45 tyrosine phosphatase. Proc. Natl. Acad. Sci. USA 87:7085.
32. Hermiston, M. L., Z. Xu, R. Majeti, and A. Weiss. 2002. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J. Clin. Invest. 109:9.
33. Horejsi, V., K. Drbal, M. Cebecauer, J. Cerny, T. Brdicka, P. Angelisova, and H. Stockinger. 1999. GPI-microdomains: a role in signalling via immunoreceptors. Immunol. Today 20:356.
34. Dykstra, M., A. Cherukuri, H. W. Sohn, S.-J. Tzeng, and S. K. Pierce. 2003. Location is everything: lipid rafts and immune cell signaling. Annu. Rev. Immunol. 21:457.
35. Simons, K., and E. Ikonen. 1997. Functional rafts in cell membranes. Nature 387:569.
36. Xavier, R., T. Brennan, Q. Li, C. McCormack, and B. Seed. 1998. Membrane compartmentation is required for efficient T cell activation. Immunity 8:723.
37. Montixi, C., C. Langlet, A. M. Bernard, J. Thimonier, C. Dubois, M. A. Wurbel, J. P. Chauvin, M. Pierres, and H. T. He. 1998. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J. 17:5334.
38. Hazenbos, W. L. W., B. E. Clausen, J. Takeda, and T. Kinoshita. 2004. GPI-anchor deficiency in myeloid cells causes impaired FcγR effector functions. Blood DOI 10.1182/blood-2004-02-0671.