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Volumn 47, Issue , 1996, Pages 1-10

Role of phosphatidylinositol-linked proteins in paroxysmal nocturnal hemoglobinuria pathogenesis

Author keywords

Complement; Hemolytic anemia; Somatic mutation

Indexed keywords

COMPLEMENT; GLYCOSYLPHOSPHATIDYLINOSITOL; MUTAGENIC AGENT; PHOSPHATIDYLINOSITOL; PROTEIN;

EID: 0029936421     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.47.1.1     Document Type: Review
Times cited : (28)

References (48)
  • 2
    • 0027386186 scopus 로고
    • The molecular basis for paroxysmal nocturnal hemoglobinuria
    • Yomtovian R, Prince GM, Medof ME. 1993. The molecular basis for paroxysmal nocturnal hemoglobinuria. Transfusion 33: 852-73
    • (1993) Transfusion , vol.33 , pp. 852-873
    • Yomtovian, R.1    Prince, G.M.2    Medof, M.E.3
  • 3
    • 0025999919 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria with onset in childhood and adolescence
    • Ware RE, Hall SE, Rosse WF. 1991. Paroxysmal nocturnal hemoglobinuria with onset in childhood and adolescence. N. Engl. J. Med. 325:991-96
    • (1991) N. Engl. J. Med. , vol.325 , pp. 991-996
    • Ware, R.E.1    Hall, S.E.2    Rosse, W.F.3
  • 4
    • 0024334289 scopus 로고
    • Decay-accelerating factor: Biochemistry, molecular biology, and function
    • Lublin DM, Atkinson JP. 1989. Decay-accelerating factor: biochemistry, molecular biology, and function. Annu. Rev. Immunol. 7:35-58
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 35-58
    • Lublin, D.M.1    Atkinson, J.P.2
  • 5
    • 0025847781 scopus 로고
    • Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster
    • Liszewski MK, Post TW, Atkinson JP. 1991. Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu. Rev. Immunol. 9:431-55
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 431-455
    • Liszewski, M.K.1    Post, T.W.2    Atkinson, J.P.3
  • 7
    • 0025952076 scopus 로고
    • The erythrocytes in paroxysmal nocturnal haemoglobinuria of intermediate sensitivity to complement lysis
    • Rosse WF, Hoffman S, Campbell M, et al. 1991. The erythrocytes in paroxysmal nocturnal haemoglobinuria of intermediate sensitivity to complement lysis. Br. J. Haematol. 79:99-107
    • (1991) Br. J. Haematol. , vol.79 , pp. 99-107
    • Rosse, W.F.1    Hoffman, S.2    Campbell, M.3
  • 8
    • 0027380002 scopus 로고
    • Diagnosis of paroxysmal nocturnal haemoglobinuria by phenotypic analysis of erythrocytes using two-colour flow cytometry with monoclonal antibodies to DAF and CD59/MACIF
    • Shichishima T, Terasawa T, Saitoh Y, et al. 1993. Diagnosis of paroxysmal nocturnal haemoglobinuria by phenotypic analysis of erythrocytes using two-colour flow cytometry with monoclonal antibodies to DAF and CD59/MACIF. Br J. Haematol. 85:378-86
    • (1993) Br J. Haematol. , vol.85 , pp. 378-386
    • Shichishima, T.1    Terasawa, T.2    Saitoh, Y.3
  • 9
    • 0025181232 scopus 로고
    • Estimation of PI-bound proteins on blood cells from PNH patients by quantitative flow cytometry
    • Plesner T, Hansen NE, Carlsen K. 1990. Estimation of PI-bound proteins on blood cells from PNH patients by quantitative flow cytometry. Br. J. Haematol. 75: 585-90
    • (1990) Br. J. Haematol. , vol.75 , pp. 585-590
    • Plesner, T.1    Hansen, N.E.2    Carlsen, K.3
  • 10
    • 0023944337 scopus 로고
    • Cell-surface anchoring of proteins via glycosylphosphatidylinositol structures
    • Ferguson MA, Williams AF. 1988. Cell-surface anchoring of proteins via glycosylphosphatidylinositol structures. Annu. Rev. Biochem. 57:285-320
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 285-320
    • Ferguson, M.A.1    Williams, A.F.2
  • 11
    • 0023871975 scopus 로고
    • Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells
    • Stafford HA, Tykocinski ML, Lublin DM, et al. 1988. Normal polymorphic variations and transcription of the decay accelerating factor gene in paroxysmal nocturnal hemoglobinuria cells. Proc. Natl. Acad. Sci. USA 85:880-84
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 880-884
    • Stafford, H.A.1    Tykocinski, M.L.2    Lublin, D.M.3
  • 12
    • 0028338781 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol anchor
    • Yeh ETH, Rosse WF. 1994. Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol anchor. J. Clin. Invest. 93:2305-10
    • (1994) J. Clin. Invest. , vol.93 , pp. 2305-2310
    • Yeh, E.T.H.1    Rosse, W.F.2
  • 13
    • 0026780907 scopus 로고
    • Synthesis of mannosyl-glucosaminyl-inositolphospholipids in normal but not paroxysmal nocturnal hemoglobinuria cells
    • Hirose S, Ravi L, Prince GM, et al. 1992. Synthesis of mannosyl-glucosaminyl-inositolphospholipids in normal but not paroxysmal nocturnal hemoglobinuria cells. Proc. Natl. Acad. Sci. USA 89:6025-29
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6025-6029
    • Hirose, S.1    Ravi, L.2    Prince, G.M.3
  • 14
    • 0026600639 scopus 로고
    • Defective glycosylphosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria granulocytes
    • Mahoney JF, Urakaze M, Hall S, et al. 1992. Defective glycosylphosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria granulocytes. Blood 79:1400-3
    • (1992) Blood , vol.79 , pp. 1400-1403
    • Mahoney, J.F.1    Urakaze, M.2    Hall, S.3
  • 15
    • 0026541823 scopus 로고
    • Deficient surface expression of glycosylphosphatidylinositol-anchored proteins in B cell lines established from patients with paroxysmal nocturnal hemoglobinuria
    • Ueda E, Nishimura J, Kitani T, et al. 1992. Deficient surface expression of glycosylphosphatidylinositol-anchored proteins in B cell lines established from patients with paroxysmal nocturnal hemoglobinuria. Int. Immunol. 4:1263-71
    • (1992) Int. Immunol. , vol.4 , pp. 1263-1271
    • Ueda, E.1    Nishimura, J.2    Kitani, T.3
  • 16
    • 0027492039 scopus 로고
    • Production and characterization of lymphoblastoid cell lines with the paroxysmal nocturnal hemoglobinuria phenotype
    • Hillmen P, Bessler M, Crawford DH, Luzzatto L. 1993. Production and characterization of lymphoblastoid cell lines with the paroxysmal nocturnal hemoglobinuria phenotype. Blood 81:193-99
    • (1993) Blood , vol.81 , pp. 193-199
    • Hillmen, P.1    Bessler, M.2    Crawford, D.H.3    Luzzatto, L.4
  • 17
    • 0027401729 scopus 로고
    • Regulation of glycoinositol phospholipid anchor assembly in human lymphocytes. Absent mannolipid synthesis in affected T and natural killer cell lines from paroxysmal nocturnal hemoglobinuria patients
    • Schubert J, Schmidt RE, Medof ME. 1993. Regulation of glycoinositol phospholipid anchor assembly in human lymphocytes. Absent mannolipid synthesis in affected T and natural killer cell lines from paroxysmal nocturnal hemoglobinuria patients. J. Biol. Chem. 268:6281-87
    • (1993) J. Biol. Chem. , vol.268 , pp. 6281-6287
    • Schubert, J.1    Schmidt, R.E.2    Medof, M.E.3
  • 18
    • 0028282431 scopus 로고
    • Interleukin-2-dependent T-cell lines established from paroxysmal nocturnal hemoglobinuria patients
    • Nakakuma H, Nagakura S, Horikawa K, et al. 1994. Interleukin-2-dependent T-cell lines established from paroxysmal nocturnal hemoglobinuria patients. Blood 84: 309-14
    • (1994) Blood , vol.84 , pp. 309-314
    • Nakakuma, H.1    Nagakura, S.2    Horikawa, K.3
  • 19
    • 0026465067 scopus 로고
    • Affected paroxysmal nocturnal hemoglobinuria T lymphocytes harbor a common defect in assembly of N-acetyl-D-glucosamine inositol phospholipid corresponding to that in class A Thy-1 murine lymphoma mutants
    • Armstrong C, Schubert J, Ueda E, et al. 1992. Affected paroxysmal nocturnal hemoglobinuria T lymphocytes harbor a common defect in assembly of N-acetyl-D-glucosamine inositol phospholipid corresponding to that in class A Thy-1 murine lymphoma mutants. J. Biol. Chem. 267: 25347-51
    • (1992) J. Biol. Chem. , vol.267 , pp. 25347-25351
    • Armstrong, C.1    Schubert, J.2    Ueda, E.3
  • 20
    • 0027412005 scopus 로고
    • Deficient biosynthesis of N-acetylglucosaminyl phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria
    • Takahashi M, Takeda J, Hirose S, et al. 1993. Deficient biosynthesis of N-acetylglucosaminyl phosphatidylinositol, the first intermediate of glycosyl phosphatidylinositol anchor biosynthesis, in cell lines established from patients with paroxysmal nocturnal hemoglobinuria. J. Exp. Med. 177:517-21
    • (1993) J. Exp. Med. , vol.177 , pp. 517-521
    • Takahashi, M.1    Takeda, J.2    Hirose, S.3
  • 21
    • 0027295959 scopus 로고
    • Impaired glycosylation of glycosylphosphatidylinositol-anchor synthesis in paroxysmal nocturnal hemoglobinuria leukocytes
    • Hidaka M, Nagakura S, Horikawa K, et al. 1993. Impaired glycosylation of glycosylphosphatidylinositol-anchor synthesis in paroxysmal nocturnal hemoglobinuria leukocytes. Biochem. Biophys. Res. Commun. 191:571-79
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 571-579
    • Hidaka, M.1    Nagakura, S.2    Horikawa, K.3
  • 22
    • 0027198876 scopus 로고
    • Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria
    • Hillmen P, Bessler M, Mason PJ, et al. 1993. Specific defect in N-acetylglucosamine incorporation in the biosynthesis of the glycosylphosphatidylinositol anchor in cloned cell lines from patients with paroxysmal nocturnal hemoglobinuria. Proc. Natl. Acad. Sci. USA 90:5272-76
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5272-5276
    • Hillmen, P.1    Bessler, M.2    Mason, P.J.3
  • 24
    • 0027412627 scopus 로고
    • Cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis
    • Miyata T, Takeda J, Iida Y, et al. 1993. Cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. Science 259:1318-20
    • (1993) Science , vol.259 , pp. 1318-1320
    • Miyata, T.1    Takeda, J.2    Iida, Y.3
  • 25
    • 0027310539 scopus 로고
    • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
    • Takeda J, Miyata T, Kawagoe K, et al. 1993. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 73:703-11
    • (1993) Cell , vol.73 , pp. 703-711
    • Takeda, J.1    Miyata, T.2    Kawagoe, K.3
  • 26
    • 0028224269 scopus 로고
    • Genomic organization of the X-linkedgene (PIG-A) that is mutated in paroxysmal nocturnal haemoglobinuria and of a related autosomal pseudogene mapped to 12q21
    • Bessler M, Hillmen P, Longo L, et al. 1994. Genomic organization of the X-linkedgene (PIG-A) that is mutated in paroxysmal nocturnal haemoglobinuria and of a related autosomal pseudogene mapped to 12q21. Hum. Mol. Genet. 3:751-57
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 751-757
    • Bessler, M.1    Hillmen, P.2    Longo, L.3
  • 27
    • 0028290901 scopus 로고
    • Characterization of genomic PIG-A gene: A gene for GPI-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria
    • Iida Y, Takeda J, Miyata T, et al. 1994. Characterization of genomic PIG-A gene: a gene for GPI-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria. Blood 83:3126-31
    • (1994) Blood , vol.83 , pp. 3126-3131
    • Iida, Y.1    Takeda, J.2    Miyata, T.3
  • 28
    • 0027309010 scopus 로고
    • Paroxysmal nocturnal haemoglobinuria: Correction of the abnormal phenotype by somatic cell hybridisation
    • Hillmen P, Bessler M, Bungey J, Luzzatto L. 1993. Paroxysmal nocturnal haemoglobinuria: correction of the abnormal phenotype by somatic cell hybridisation. Somat. Cell Mol. Genet. 19:123-29
    • (1993) Somat. Cell Mol. Genet. , vol.19 , pp. 123-129
    • Hillmen, P.1    Bessler, M.2    Bungey, J.3    Luzzatto, L.4
  • 29
    • 0028123686 scopus 로고
    • Glycosyl-phosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria: Partial or complete defect in an early step
    • Norris J, Hall S, Ware RE, et al. 1994. Glycosyl-phosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria: partial or complete defect in an early step. Blood 83:816-21
    • (1994) Blood , vol.83 , pp. 816-821
    • Norris, J.1    Hall, S.2    Ware, R.E.3
  • 30
    • 0028057618 scopus 로고
    • Abnormalities of PIG-A transcripts in granulocytes from patients with paroxysmal nocturnal hemoglobinuria
    • Miyata T, Yamada N, Iida Y, et al. 1994. Abnormalities of PIG-A transcripts in granulocytes from patients with paroxysmal nocturnal hemoglobinuria. N. Engl. J. Med. 330:249-55
    • (1994) N. Engl. J. Med. , vol.330 , pp. 249-255
    • Miyata, T.1    Yamada, N.2    Iida, Y.3
  • 31
    • 0028897279 scopus 로고
    • Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria
    • Yamada N, Miyata T, Maeda K, et al. 1995. Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria. Blood 85: 885-92
    • (1995) Blood , vol.85 , pp. 885-892
    • Yamada, N.1    Miyata, T.2    Maeda, K.3
  • 32
    • 0028057807 scopus 로고
    • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene
    • Bessler M, Mason PJ, Hillmen P, et al. 1994. Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene. EMBO J. 13: 110-17
    • (1994) EMBO J. , vol.13 , pp. 110-117
    • Bessler, M.1    Mason, P.J.2    Hillmen, P.3
  • 33
    • 0028299834 scopus 로고
    • Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria
    • Bessler M, Mason P, Hillmen P, Luzzatto L. 1994. Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria. Lancet 343:951-53
    • (1994) Lancet , vol.343 , pp. 951-953
    • Bessler, M.1    Mason, P.2    Hillmen, P.3    Luzzatto, L.4
  • 34
    • 0028110863 scopus 로고
    • Mutations in the PIG-A gene causing partial deficiency of GPI-linked surface proteins (PNH II) in patients with paroxysmal nocturnal haemoglobinuria
    • Bessler M, Mason PJ, Hillmen P, Luzzatto L. 1994. Mutations in the PIG-A gene causing partial deficiency of GPI-linked surface proteins (PNH II) in patients with paroxysmal nocturnal haemoglobinuria. Br. J. Haematol. 87:863-66
    • (1994) Br. J. Haematol. , vol.87 , pp. 863-866
    • Bessler, M.1    Mason, P.J.2    Hillmen, P.3    Luzzatto, L.4
  • 35
    • 0028907854 scopus 로고
    • Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria
    • Ostendorf T, Nischan C, Schubert J, et al. 1995. Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria. Blood 85:1640-46
    • (1995) Blood , vol.85 , pp. 1640-1646
    • Ostendorf, T.1    Nischan, C.2    Schubert, J.3
  • 36
    • 0028353422 scopus 로고
    • Mutations within the Piga gene in patients with paroxysmal nocturnal hemoglobinuria
    • Ware RE, Rosse WF, Howard TA. 1994. Mutations within the Piga gene in patients with paroxysmal nocturnal hemoglobinuria. Blood 83:2418-22
    • (1994) Blood , vol.83 , pp. 2418-2422
    • Ware, R.E.1    Rosse, W.F.2    Howard, T.A.3
  • 37
    • 0028911097 scopus 로고
    • PIG-A, DAF and protooncogene expression in paroxysmal nocturnal haemoglobinuria-associated acute myelogenous leukaemia blasts
    • Stafford HA, Nagarajan S, Weinberg JB, Medof ME. 1995. PIG-A, DAF and protooncogene expression in paroxysmal nocturnal haemoglobinuria-associated acute myelogenous leukaemia blasts. Br. J. Haematol. 89:72-78
    • (1995) Br. J. Haematol. , vol.89 , pp. 72-78
    • Stafford, H.A.1    Nagarajan, S.2    Weinberg, J.B.3    Medof, M.E.4
  • 38
    • 0029163277 scopus 로고
    • Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria
    • In press
    • Pramoonjago P, Wanachiwanawin W, Chinprasertsak S, et al. 1995. Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria. Blood 86:In press
    • (1995) Blood , vol.86
    • Pramoonjago, P.1    Wanachiwanawin, W.2    Chinprasertsak, S.3
  • 39
    • 0028228227 scopus 로고
    • Chromosomal assignment of genes involved in glycosylphosphatidylinositol anchor biosynthesis: Implications for the pathogenesis of paroxysmal nocturnal hemoglobinuria
    • Ware RE, Howard TA, Kamitani T, et al. 1994. Chromosomal assignment of genes involved in glycosylphosphatidylinositol anchor biosynthesis: implications for the pathogenesis of paroxysmal nocturnal hemoglobinuria. Blood 83:3753-57
    • (1994) Blood , vol.83 , pp. 3753-3757
    • Ware, R.E.1    Howard, T.A.2    Kamitani, T.3
  • 40
    • 0028845489 scopus 로고
    • Structure and chromosomal localization of the GPI-anchor synthesis gene PIG-F and its pseudogene ψ PIG-F
    • In press
    • Ohishi K, Inoue N, Endo Y, et al. 1995. Structure and chromosomal localization of the GPI-anchor synthesis gene PIG-F and its pseudogene ψ PIG-F. Genomics 28:In press
    • (1995) Genomics , vol.28
    • Ohishi, K.1    Inoue, N.2    Endo, Y.3
  • 41
    • 0014832992 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria: Evidence for monoclonal origin of abnormal red cells
    • Oni SB, Osunkoya BO, Luzzatto L. 1970. Paroxysmal nocturnal hemoglobinuria: evidence for monoclonal origin of abnormal red cells. Blood 36:145-52
    • (1970) Blood , vol.36 , pp. 145-152
    • Oni, S.B.1    Osunkoya, B.O.2    Luzzatto, L.3
  • 42
    • 0026352128 scopus 로고
    • Acquired aplastic anemia and paroxysmal nocturnal hemoglobinuria: Studies on clonality
    • Josten KM, Tooze JA, Borthwick-Clarke C, et al. 1991. Acquired aplastic anemia and paroxysmal nocturnal hemoglobinuria: studies on clonality. Blood 78:3162-67
    • (1991) Blood , vol.78 , pp. 3162-3167
    • Josten, K.M.1    Tooze, J.A.2    Borthwick-Clarke, C.3
  • 43
    • 0026690425 scopus 로고
    • Clonal origin of abnormal granulocytes in paroxysmal nocturnal hemoglobinuria
    • Bessler M, Hillmen P, Luzzatto L. 1992. Clonal origin of abnormal granulocytes in paroxysmal nocturnal hemoglobinuria. Blood 80:844-45
    • (1992) Blood , vol.80 , pp. 844-845
    • Bessler, M.1    Hillmen, P.2    Luzzatto, L.3
  • 44
    • 0027980005 scopus 로고
    • Peripheral blood cells are predominantly chimeric of affected and normal cells in patients with paroxysmal nocturnal hemoglobinuria: Simultaneous investigation on clonality and expression of glycophosphatidylinositol-anchored proteins
    • Ohashi H, Hotta T, Ichikawa A, et al. 1994. Peripheral blood cells are predominantly chimeric of affected and normal cells in patients with paroxysmal nocturnal hemoglobinuria: simultaneous investigation on clonality and expression of glycophosphatidylinositol-anchored proteins. Blood 83: 853-59
    • (1994) Blood , vol.83 , pp. 853-859
    • Ohashi, H.1    Hotta, T.2    Ichikawa, A.3
  • 45
    • 0027160839 scopus 로고
    • Defective and normal haematopoietic stem cells in paroxysmal nocturnal haemoglobinuria
    • Terstappen L, Nguyen M, Huang S, et al. 1993. Defective and normal haematopoietic stem cells in paroxysmal nocturnal haemoglobinuria. Br. J. Haematol. 84: 504-14
    • (1993) Br. J. Haematol. , vol.84 , pp. 504-514
    • Terstappen, L.1    Nguyen, M.2    Huang, S.3
  • 46
    • 0028046590 scopus 로고
    • Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function and gene locus
    • Kawagoe K, Takeda J, Endo Y, Kinoshita T. 1994. Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function and gene locus. Genomics 23:566-74
    • (1994) Genomics , vol.23 , pp. 566-574
    • Kawagoe, K.1    Takeda, J.2    Endo, Y.3    Kinoshita, T.4
  • 47
    • 0028295447 scopus 로고
    • Development of the glycosylphosphatidylinositol-anchoring defect characteristic for paroxysmal nocturnal hemoglobinuria in patients with aplastic anemia
    • Schubert J, Vogt HG, Zielinska Skowronek M, et al. 1994. Development of the glycosylphosphatidylinositol-anchoring defect characteristic for paroxysmal nocturnal hemoglobinuria in patients with aplastic anemia. Blood 83:2323-28
    • (1994) Blood , vol.83 , pp. 2323-2328
    • Schubert, J.1    Vogt, H.G.2    Zielinska Skowronek, M.3
  • 48
    • 0025865140 scopus 로고
    • Treatment of aplastic anemia with antilymphocyte globulin and methylprednisolone with or without cyclosporine
    • Frickhofen N, Kaltwasser JP, Schrezenmeier H, et al. 1991. Treatment of aplastic anemia with antilymphocyte globulin and methylprednisolone with or without cyclosporine. N. Engl. J. Med. 324:1297-304
    • (1991) N. Engl. J. Med. , vol.324 , pp. 1297-1304
    • Frickhofen, N.1    Kaltwasser, J.P.2    Schrezenmeier, H.3


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