What do herbalists suggest to diabetic patients in order to improve glycemic control? Evaluation of scientific evidence and potential risks

Acta Diabetologica

Volumn 41, Issue 3, 2004, Pages 91-98

  Cicero, A F G ^a   Derosa, G ^b   Gaddi, A ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Complementary medicine; Diabetes mellitus; Dietary supplements; Efficacy; Herbal remedies; Herbalist; Safety

Indexed keywords

ALPHA TOCOPHEROL; AMIODARONE; ASCORBIC ACID; BILBERRY EXTRACT; BIOTIN; BURDOCK EXTRACT; CHROMIUM; CISPLATIN; DANDELION EXTRACT; FRUCTOSE OLIGOSACCHARIDE; GARLIC EXTRACT; GINSENG EXTRACT; GYMNEMA EXTRACT; HERBACEOUS AGENT; ISPAGULA; LEVODOPA; MOMORDICA CHARANTIA EXTRACT; OPUNTIA EXTRACT; PHENYTOIN; PLANT EXTRACT; PYRIDOXINE 2 OXOGLUTARATE; PYRIDOXINE DERIVATIVE; SELENIUM; THIOCTIC ACID; TRIGONELLA FOENUM GRAECUM EXTRACT; UNCLASSIFIED DRUG; VANADIUM;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; ADULT; ALTERNATIVE MEDICINE; ANEMIA; BIPOLAR DISORDER; BITTER TASTE; BLOOD GLUCOSE MONITORING; CLINICAL TRIAL; CONSULTATION; CONTINUING EDUCATION; CREATININE BLOOD LEVEL; DIABETES CONTROL; DIABETES MELLITUS; DIARRHEA; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG MECHANISM; DRUG SAFETY; ESOPHAGUS OBSTRUCTION; EVIDENCE BASED MEDICINE; FATIGUE; FEMALE; FLATULENCE; GASTROINTESTINAL SYMPTOM; GLUCOSE INTOLERANCE; HALITOSIS; HEADACHE; HERBAL MEDICINE; HUMAN; HYPERTENSION; HYPOGLYCEMIA; INCREASED APPETITE; INSOMNIA; INTERVIEW; INTESTINE OBSTRUCTION; IRRITABILITY; ITALY; KIDNEY FAILURE; LIVER TOXICITY; MALE; MEDICAL EDUCATION; MUSCLE CRAMP; MYALGIA; NAUSEA; NERVOUSNESS; NEUROPATHY; NORMAL HUMAN; ODOR; PARESTHESIA; PATIENT EDUCATION; PERIPHERAL NEUROPATHY; PRESCRIPTION; PRIORITY JOURNAL; QUESTIONNAIRE; REVIEW; RISK; SIDE EFFECT; SKIN ALLERGY; TASTE DISORDER; THROMBOCYTOPENIA; UREMIA; WEIGHT REDUCTION;

BLOOD GLUCOSE; DIABETES MELLITUS; DIETARY SUPPLEMENTS; HUMANS; ITALY; MEDICINE, HERBAL; PHYTOTHERAPY; VITAMINS;

EID: 4644286292     PISSN: 09405429     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00592-004-0150-2     Document Type: Review

References (64)

1. Bean WB (1961) Sir William Osler: Aphorisms from his bedside teachings and writings. Charles C. Thomas, Springfield, p 105
2. Capasso L (1998) 5300 years ago, the Ice Man used natural laxatives and antibiotics. Lancet 352:1864
3. Goldman P (2001) Herbal medicine today and the roots of modern pharmacology. Ann Intern Med 135:594-600
4. Rees L, Weil A (2001) Integrated medicine. BMJ 322:119-120
5. Astin JA (1998) Why patients use alternative medicine. JAMA 279:1548-1553
6. Scott GN, Elmer GW (2002) Update on natural product-drug interactions. Am J Health Syst Pharm 59(4):339-347
7. Kaufman DW, Kelly JP, Rosenberg L, Andrerson TE, Mitchell AA (2002) Recent patterns of medication use in the ambulatory adult population of the United States. The Slone Survey. JAMA 287(3):337-344
8. Blumenthal M, Busse WR, Goldberg A (1998) The Complete German Commission E monographs: therapeutic guide to herbal medicines. American Botanical Council, Austin
9. Blumenthal M, Goldberg A, Brinkmann J (2000) Herbal medicine. Expanded Commission E Monographs. American Botanical Council, Austin
10. Bruneton J (1999) Pharmacognosie, phytochimie, plantes médicinales. Editions Internationales Médicales, Cachan
11. Haensel R, Sticher O, Steineger E (1999) Pharmakognosie-Phytopharmazie. Springer, Berlin Heidelberg New York
12. Barnes J, Anderson LA, Philipson JD (2002) Herbal medicines, 2nd edn. Pharmaceutical Press, Oxon
13. Mason P (2002) Dietary supplements, 2nd edn. Pharmaceutical Press, Oxon
14. Rapport L, Lockwood B (2002) Nutraceuticals. Pharmaceutical Press, Oxon
15. Brala PM, Hagen RL (1983) Effects of sweetness perception and calorie value of a preload on short term intake. Physiol Behav 30(1):1-9
16. Miyasaka A, Imoto T (1995) Electrophysiological characterization of the inhibitory effect of a novel peptide gumarin on the sweet taste response in rats. Brain Res 676(1):63-68
17. Shanmugasundaram ER, Rajeswari G, Baskaran K et al (1990) Use of Gymnema sylvestre leaf extracts in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 30(3):281-284
18. Baskaran K, Kizar Ahamath B, Shanmugasundaram KR, Rajeswari G (1990) Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 30(3):295-300
19. Suttisri R, Lee IS, Kinghorn AD (1995) Plant-derived triterpenoid sweetness inhibitors. J Ethnopharmacol 47(1):9-26
20. Shanmugasundaram ER, Gopinath KL, Shanmugasundaram KR et al (1990) Possible regeneration of the islets of Langerhams in streptozocin-diabetic rats given Gymnema sylvestre leaf extracts. J Ethnopharmacol 30(3):265-279
21. Pastors JG, Blaisdell PW, Balm TK et al (1991) Psyllium fiber reduces rise in postprandial glucose and insulin oncentrations in patients with non-insulin-dependent diabetes. Am J Clin Nutr 53(6):1431-1435
22. Wolever TMS, Vuksan V, Eshuis H et al (1991) Effect of method of administration on psyllium on glycaemic response and carbohydrate digestibility. J Am Coll Nutr 10(4):364-371
23. Neeraja A, Rajyalakshmi P (1996) Hypoglycaemic effect of processed fenugreek seeds in humans. J Food Sci Technol 33(5):427-430
24. Sharma RD, Sarkar A, Hazra DK et al (1996) Use of fenugreek seed powder in the management of non-insulin dependent diabetes mellitus. Nutr Res 16(8):1331-1339
25. Al-Habori M, Raman A (1998) Antidiabetic and hypocholesterolaemic effects of fenugreek. Phytother Res 12:233-242
26. Sharma RD, Raghuram TC, Sudhakar R (1990) Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 44:301-306
27. Vats V, Yadav SP, Grover JK (2003) Effect of T. foenumgraecum on glycogen content of tissues and the key enzymes of carbohydrate metabolism. J Ethnopharmacol 85(2-3):237-242
28. Basch E, Gabardi S, Ulbricht C (2003) Bitter melon (Monordica charantia): a review of efficacy and safety. Am J Health Syst Pharm 60(4):356-359
29. Kiesewetter H, Jung F, Pindur G, Jung EM, Mrowietz C, Wenzel E (1991) Effect of garrlic on thrombocyte aggregation, microcirculation and other risk factors. Int J Clin Pharmacol Ther Toxicol 29:151-155
30. Sotaniemi E, Haapakoski E, Rautio A (1995) Ginseng therapy in non-insulin dependent diabetic patients. Diabetes Care 18:1373-1375
31. Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Puch W, Polonsky KS, Yuan CS (2002) Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes 51(6):1851-1858
32. Frati AC, Gordil BE, Altamirano P et al (1990) Acute hypoglycaemic effect of Opuntia streptacantha Lemaire in NIDDM. Diabetes Care 13(4):455-456
33. Srivastava Y, Venkatakrishna-Bhatt H, Verma Y et al (1993) Antidiabetic and adaptogenic properties of Momordica-charantia extract: an experimental and clinical evaluation. Phytother Res 7:285-289
34. Lapinina LO, Sisoeva TF (1964) Investigation of some plants to determine their sugar lowering action. Farmatsevt Zh 19:52-58
35. Akhtar MS (1985) Effects of Protulaca oleracae (kulfa) and Taraxacyum officinale (dhundal) in normoglycaemic and alloxan-treated hyperglycaemic rabbits. J Pak Med Assoc 35:207-210
36. Koutsikos D, Agroyaniis B, Tzanatos-Exarchou H (1990) Biotin for diabetic peripheral neuropathy. Biomed Pharmacother 44(10):511-514
37. Zhang H, Osada K, Sone H et al (1997) Biotin administration improves the impaired glucose tolerance of streptozotocin-induced diabetic Wistar rats. J Nutr Sci Vitaminol 43(3):271-280
38. McCarty MF (2000) Toward a wholly nutritional therapy for type 2 diabetes. Med Hypotheses 54(3):483-487
39. Boden G, Chen X, Ruiz J et al (1996) Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 45(9):1130-1135
40. Conconi MT, DeCarlo E, Vigolo S, Grandi C, Bandoli G, Sicolo N, Tamagno G, Parnigotto PP, Nussdorfer GG (2003) Effects of some vanadyl coordination compounds on the in vitro insulin release from rat pancreatic islets. Horm Metab Res 35(7):402-406
41. Fox GN, Sabovic Z (1998) Chromium picolinate supplementation for diabetes mellitus. J Fam Pract 46(1):83-86
42. Anderson RA, Cheng N, Bryden NA et al (1997) Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes 46(11):1786-1791
43. Ryan GJ, Wanko NS, Redman AR, Cook CB (2003) Chromium as adjunctive treatment for type 2 diabetes. Ann Pharmacother 37(6):876-885
44. Spellacy WN, Buhi WC, Birk SA (1972) The effects of vitamin B6 on carbohydrate metabolism in women taking steroid contraceptives: preliminary report. Contraception 6(4):265-273
45. Spellacy WN, Buhi WC, Birk SA (1977) Vitamin B6 treatment of gestational diabetes mellitus: studies of blood glucose and plasma insulin. Am J Obstet Gynecol 127(6):599-602
46. Passariello N, Fici F, Giugliano D (1983) Effects of pyridoxine alpha-ketoglutarate on blood glucose and lactate in type I and II diabetics. Int J Clin Pharmacol Ther Toxicol 21(5):252-256
47. Jain SK, Lim G (2001) Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes. Free Radic Biol Med 30(3):232-237
48. Will JC, Byers T (1996) Does diabetes mellitus increase the requirement for vitamin C? Nutr Rev 54(7):193-202
49. Cunningham JJ, Mearkle PL, Brown RG (1994) Vitamin C: an aldose reductase inhibitor that normalizes erythrocyte sorbitol in insulin-dependent diabetes mellitus. J Am Coll Nutr 13(4):344-350
50. Evans M, Anderson RA, Smith JC, Khan N, Graham JM, Thomas AW, Morris K, Deely D, Frenneaux MP, Davies JS, Rees A (2003) Effects of insulin lispro and chronic vitamin C therapy on postprandial lipaemia, oxidative stress and endothelial function in patients with type 2 diabetes mellitus. Eur J Clin Invest 33(3):231-238
51. Ohrvall M, Nalsen C, Vessby B (1997) Vitamin E improves the antioxidative capacity but not the insulin sensitivity in elderly men. Nutr Metab Cardiovasc Dis 7:9-15
52. Cunningham JJ (1998) Micronutrients as nutriceutical interventions in diabetes mellitus. J Am Coll Nutr 17(1):7-10
53. Ametov AS, Barinov A, Dyck PJ, Hermann R, Kozlova N, Litchy WJ, Low PA, Nehrdich D, Novosadova M, O'Brien PC, Reljanovic M, Samigullin R, Schuette K, Strokov I, Tritschler HJ, Wessel K, Yakhno N, Ziegler D; SYDNEY Trial Study Group (2003) The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid: the SYDNEY trial. Diabetes Care 26(3):770-776
54. Borcea V, Nourooz-Zadeh J, Wolff SP et al (1999) Alpha-lipoic acid decreases oxidative stress even in diabetic patients with poor glycaemic control and albuminuria. Free Radic Biol Med 22(11-12):1495-1500
55. Yamashita K, Kawai K, Itakura M (1984) Effects of fructooligosaccharides on blood glucose and serum lipids in diabetic subjects. Nutr Res 4:961-966
56. Alles MS, de Roos NM, Bakx JC, van de Lisdonk E, Zock PL, Hautvast GA (1999) Consumption of fructooligosaccharides does not favorably affect blood glucose and serum lipid concentrations in patients with type 2 diabetes. Am J Clin Nutr 69(1):64-69
57. Luo J, Van Yperselle M, Rizkalla SW, Rossi F, Bomet FR, Slama G (2000). Chronic consumption of short-chain fructooligosaccharides does not affect basal hepatic glucose production or insulin resistance in type 2 diabetics. J Nutr 130(6):1572-1577
58. Adams KE, Cohen MH, Eisenberg D, Jonsen AR (2002) Ethical considerations of complementary and alternative medical therapies in conventional medical settings. Ann Intern Med 137(8):660-664
59. Egede LE, Ye X, Zheng D, Silverstein M (2002) The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes. Diabetes Care 25(2):324-329
60. Yeh GY, Eisenberg DM, Davis RB, Phillips RS (2002) Use of complementary and alternative medicine among persons with diabetes mellitus: results of a national survey. Am J Public Health 92(10):1648-1652
61. Patel RP, Taylor SD (2002) Factors affecting medication adherence in hypertensive patients. Ann Pharmacother 36(1):40-45
62. Gray CM, Tan AW, Pronk NP, O'Connor PJ (2002) Complementary and alternative medicine use among health plan members. A cross-sectional survey. Eff Clin Pract 5(1):17-22
63. Eisenberg DM, Kessler RC, Van Rompay MI, Kaptchuk TJ, Wilkey SA, Appel S, Davis RB (2001) Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a national survey. Ann Intern Med 135(5):344-351
64. Owen DK, Lewith G, Stephens CR (2001) Can doctors respond to patients' increasing interest in complementary and alternative medicine? BMJ 322:134-138