Transcriptional repression by the bHLH-Orange factor XHRT1 does not involve the C-terminal YRPW motif

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1680, Issue 1, 2004, Pages 46-52

  Pichon, Bruno ^a   Taelman, Vincent ^b   Bellefroid, Eric J ^b   Christophe, Daniel ^a,c  

^a B 6041 Gosselies   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c IBMM   (Belgium)

Author keywords

bHLH; Groucho; HES; HRT; Transcription; XHRT1

Indexed keywords

AMINO ACID; HELIX LOOP HELIX PROTEIN; LUCIFERASE; TYROSYLARGINYLPROLYLTRYPTOPHAN; UNCLASSIFIED DRUG; XENOPUS HAIRY RELATED TRANSCRIPTION FACTOR 1;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN 3T3; CONTROLLED STUDY; DNA BINDING MOTIF; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; REPORTER GENE;

AMINO ACID MOTIFS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MICE; NIH 3T3 CELLS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS; XENOPUS PROTEINS;

EID: 4644278601     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2004.08.010     Document Type: Article

References (32)

1. J.S. Mumm, and R. Kopan Notch signaling: from the outside in Dev. Biol. 228 2000 151 165
2. R.L. Davis, and D.L. Turner Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning Oncogene 20 2001 8342 8357
3. T. Iso, L. Kedes, and Y. Hamamori HES and HERP families: multiple effectors of the Notch signaling pathway J. Cell. Physiol. 194 2003 237 255
4. G. Chen, and A.J. Courey Groucho/TLE family proteins and transcriptional repression Gene 249 2000 1 16
5. P. Castella, S. Sawai, K. Nakao, J.A. Wagner, and M. Caudy HES-1 repression of differentiation and proliferation in PC12 cells: role for the helix 3-helix 4 domain in transcription repression Mol. Cell. Biol. 20 2000 6170 6183
6. O. Nakagawa, M. Nakagawa, J. Richardson, E.N. Olson, and D. Strivastava HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic and pharyngeal arch segments Dev. Biol. 216 1999 72 84
7. H. Kokubo, Y. Lun, and R.L. Johnson Identification and expression of a novel family of bHLH cDNAs related to Drosophila Hairy and Enhancer of split Biochem. Biophys. Res. Commun. 260 1999 459 465
8. C. Leimeister, A. Externbrink, B. Klamt, and M. Gessler Hey genes: a novel subfamily of hairy- and Enhancer of split-related genes specifically expressed during mouse embryogenesis Mech. Dev. 85 1999 173 177
9. M.T. Chin, K. Maemura, S. Fukumoto, M.K. Jain, M.D. Layne, M. Watanabe, C.-M. Hsieh, and M.-E. Lee Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system J. Biol. Chem. 275 2000 6381 6397
10. T.P. Zhong, M. Rosenberg, M.-A.P.K. Mohideen, B. Weinstein, and M.C. Fishman Gridlock, an HLH gene required for assembly of the aorta in zebrafish Science 287 2000 1820 1824
11. T. Iso, V. Sartorelli, G. Chung, T. Shichinohe, L. Kedes, and Y. Hamamori HERP, a new primary target of Notch regulated by ligand binding Mol. Cell. Biol. 21 2001 6071 6079
12. T. Iso, V. Sartorelli, C. Poizat, S. Iezzi, H.-Y. Wu, G. Chung, L. Kedes, and Y. Hamamori HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling Mol. Cell. Biol. 21 2001 6080 6089
13. O. Nakagawa, D.G. Mc Fadden, M. Nakagawa, H. Yanagisawa, T. Hu, D. Srivastava, and E.N. Olson Members of the HRT family of basic helix-loop-helix protein act as transcriptional repressors downstream of Notch signaling Proc. Natl. Acad. Sci. U. S. A. 97 2000 13655 13660
14. J. Sun, C. Kamei, M.D. Layne, M.K. Jain, J.K. Liao, M.-E. Lee, and M. Chin Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2 J. Biol. Chem. 276 2001 18591 18596
15. A.M. Henderson, S.J. Wang, A.C. Taylor, M. Aitkenhead, and C.C. Hughes The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation J. Biol. Chem. 276 2001 6169 6176
16. M. Gessler, K.P. Knobeloch, A. Helisch, K. Amann, N. Schumacher, E. Rohde, A. Fischer, and C. Leimeister Mouse gridlock: no aortic coarctation or deficiency, but fatal cardiac defects in Hey2 -/- mice Curr. Biol. 12 2002 1601 1604
17. Y. Sakata, C.N. Kamei, H. Nakagami, R. Bronson, J.K. Liao, and M.T. Chin Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2 Proc. Natl. Acad. Sci. U. S. A. 99 2002 16197 16202
18. C. Leimeister, K. Dale, A. Fisher, B. Klamt, M.H. de Angelis, F. Radtke, M.J. McGrew, O. Pourquié, and M. Gessler Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors Dev. Biol. 227 2000 91 103
19. T. Satow, S.K. Bae, T. Inoue, C. Inoue, G. Miyoshi, K. Tomita, Y. Bessho, N. Hashimoto, and R. Kageyama The basic helix-loop-helix gene hesr2 promotes gliogenesis in mouse retina J. Neurosci. 21 2001 1265 1273
20. A.L. Fisher, and M. Caudy Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates Genes Dev. 12 1998 1931 1940
21. B. Pichon, V. Taelman, S. Kricha, D. Christophe, and E.J. Bellefroid XHRT-1, a hairy and Enhancer of split related gene with expression in floor plate and hypochord during early Xenopus embryogenesis Dev. Genes Evol. 212 2002 491 495
22. A.B. Lassar, J.N. Buskin, D. Lockshon, R.L. Davis, S. Apone, S.D. Hauschka, and H. Weintraub MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer Cell 58 1989 823 831
23. P.M. Chevray, and D. Nathans Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun Proc. Natl. Acad. Sci. U. S. A. 89 1992 5789 5793
24. J. Muhr, E. Andersson, M. Persson, T.M. Jessell, and J. Ericson Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube Cell 104 2001 861 873
25. H. Mircescu, S. Steuve, V. Savonet, C. Degraef, H. Mellor, J.E. Dumont, C. Maenhaut, and I. Pirson Identification characterization of a novel activated RhoB binding protein containing a PDZ domain and whose expression is specifically modulated in thyroid cells by cAMP Eur. J. Biochem. 269 2000 6241 6249
26. L.-H. Li, C. Nerlov, G. Prendergast, D. MacGregor, and E.B. Ziff c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II EMBO J. 13 1994 4070 4079
27. S. Ohsako, J. Hyer, G. Panganiban, I. Oliver, and M. Caudy hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation Genes Dev. 8 1994 2743 2755
28. Y. Sasai, R. Kageyama, Y. Tagawa, R. Shigemoto, and S. Nakanishi Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split Genes Dev. 6 1992 2620 2634
29. E. Schreiber, P. Matthias, M.M. Müller, and W. Schaffner Rapid detection of octamer binding proteins with "mini-extracts" prepared from a small number of cells Nucleic Acids Res. 17 1989 6419
30. T.K. Blackwell, and H. Weintraub Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection Science 250 1990 1104 1110
31. A. Fischer, C. Leimeister, C. Winkler, N. Schumacher, B. Klamt, H. Elmasri, C. Steidl, M. Maier, K.-P. Knobeloch, K. Amann, A. Helisch, M. Sendtner, and M. Gessler Hey bHLH factors in cardiovascular development Cold Spring Harbor Symp. Quant. Biol. 67 2002 63 70
32. A.L. Fisher, S. Ohsako, and M. Caudy The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino acid transcription repression and protein-protein interaction domain Mol. Cell. Biol. 16 1996 2670 2677