Activin, inhibin and the human breast

Molecular and Cellular Endocrinology

Volumn 225, Issue 1-2, 2004, Pages 77-82

  Reis, F M ^a   Luisi, S ^b   Carneiro, M M ^a   Cobellis, L ^b   Federico, M ^c   Camargos, A F ^a   Petraglia, F ^b  

^a Belo   (Brazil)

^b UNIVERSITY OF SIENA   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Activin; Breast; Breast cancer; Inhibin; Lactation; Mammary gland

Indexed keywords

ACTIVIN; ACTIVIN A; BINDING PROTEIN; BIOCHEMICAL MARKER; CHORIONIC GONADOTROPIN; FOLLISTATIN; GROWTH FACTOR; INHIBIN;

BREAST; BREAST CANCER; BREAST CARCINOMA; BREAST FIBROADENOMA; BREAST MILK; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONFERENCE PAPER; CYSTIC FIBROSIS; GENE EXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; LACTATION; MENOPAUSE; MENSTRUAL CYCLE; MITOSIS INHIBITION; MORPHOGENESIS; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION;

ACTIVINS; BREAST; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INHIBIN-BETA SUBUNITS; INHIBINS; PROTEIN SUBUNITS;

EID: 4644256749     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2004.02.016     Document Type: Conference Paper

References (32)

1. Alvarado M.V., Alvarado N.E., Russo J., Russo I.H. Human chorionic gonadotropin inhibits proliferation and induces expression of inhibin in human breast epithelial cells in vitro. In Vitro Cell Dev. Biol. Anim. 30A:1994;4-8
2. Alvarado M.V., Russo J., Russo I.H. Immunolocalization of inhibin in the mammary gland of rats treated with hCG. J. Histochem. Cytochem. 41:1993;29-34
3. Ball E.M., Risbridger G.P. Activins as regulators of branching morphogenesis. Dev. Biol. 238:2001;1-12
4. Bernard D.J., Chapman S.C., Woodruff T.K. Mechanisms of inhibin signal transduction. Recent Prog. Horm. Res. 56:2001;417-450
5. Caniggia I., Lye S.J., Cross J.C. Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology. 138:1997;3976-3986
6. Charpentier A.H., Bednarek A.K., Daniel R.L., Hawkins K.A., Laflin K.J., Gaddis S., MacLeod M.C., Aldaz C.M. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res. 60:2000;5977-5983
7. Cocolakis E., Lemay S., Ali S., Lebrun J.J. The p38 MAPK pathway is required for cell growth inhibition of human breast cancer cells in response to activin. J. Biol. Chem. 276:2001;18430-18436
8. Danila D.C., Inder W.J., Zhang X., Alexander J.M., Swearingen B., Hedley-Whyte E.T., Klibanski A. Activin effects on neoplastic proliferation of human pituitary tumors. J. Clin. Endocrinol. Metab. 85:2000;1009-1015
9. de Kretser D.M., Hedger M.P., Phillips D.J. Activin A and follistatin: their role in the acute phase reaction and inflammation. J. Endocrinol. 161(195-198):1999;195-198
10. de Winter J.P., Roelen B.A., ten Dijke P., van der B.B., van den Eijnden-van Raaij A.J. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells. Oncogene. 14:1997;1891-1899
11. Di Loreto C., Reis F.M., Cataldi P., Zuiani C., Luisi S., Beltrami C.A., Petraglia F. Human mammary gland and breast carcinoma contain immunoreactive inhibin/activin subunits: evidence for a secretion into cystic fluid. Eur. J. Endocrinol. 141:1999;190-194
12. Florio P., Luisi S., Vigano P., Busacca M., Fadalti M., Genazzani A.R., Petraglia F. Healthy women and patients with endometriosis show high concentrations of inhibin A, inhibin B, and activin A in peritoneal fluid throughout the menstrual cycle. Hum. Reprod. 13:1998;2606-2611
13. Groome N.P., Illingworth P.J., O'Brien M., Pai R., Rodger F.E., Mather J.P., McNeilly A.S. Measurement of dimeric inhibin B throughout the human menstrual cycle. J. Clin. Endocrinol. Metab. 81:1996;1401-1405
14. Ho T.Y., Russo J., Russo I.H. Polypeptide pattern of human breast epithelial cells following human chorionic gonadotropin (hCG) treatment. Electrophoresis. 15:1994;746-750
15. Jiang X., Russo I.H., Russo J. Human chorionic gonadotropin and inhibin induce histone acetylation in human breast epithelial cells. Int. J. Oncol. 20:2002;77-79
16. Kalkhoven E., Roelen B.A., de Winter J.P., Mummery C.L., van den Eijnden-van Raaij A.J., van der Saag P.T., van der B.B. Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines. Cell Growth Differ. 6:1995;1151-1161
17. Keelan J.A., Zhou R.L., Mitchell M.D. Activin A exerts both pro- and anti-inflammatory effects on human term gestational tissues. Placenta. 21:2000;38-43
18. Li Q., Karam S.M., Coerver K.A., Matzuk M.M., Gordon J.I. Stimulation of activin receptor II signaling pathways inhibits differentiation of multiple gastric epithelial lineages. Mol. Endocrinol. 12:1998;181-192
19. Liu Q.Y., Niranjan B., Gomes P., Gomm J.J., Davies D., Coombes R.C., Buluwela L. Inhibitory effects of activin on the growth and morpholgenesis of primary and transformed mammary epithelial cells. Cancer Res. 56:1996;1155-1163
20. Luisi S., Calonaci G., Florio P., Lombardi I., De Felice C., Bagnoli F., Petraglia F. Identification of activin A and follistatin in human milk. Growth Factors. 20:2002;147-150
21. McPherson S.J., Mellor S.L., Wang H., Evans L.W., Groome N.P., Risbridger G.P. Expression of activin A and follistatin core proteins by human prostate tumor cell lines. Endocrinology. 140:1999;5303-5309
22. Peng C., Mukai S.T. Activins and their receptors in female reproduction. Biochem. Cell Biol. 78:2000;261-279
23. Petraglia F., Sacerdote P., Cossarizza A., Angioni S., Genazzani A.D., Franceschi C. Inhibin and activin modulate human monocyte chemotaxis and human lymphocyte interferon-gamma production. J. Clin. Endocrinol. Metab. 72(496-502):1991;496-502
24. Reinholz M.M., Iturria S.J., Ingle J.N., Roche P.C. Differential gene expression of TGF-beta family members and osteopontin in breast tumor tissue: analysis by real-time quantitative PCR. Breast Cancer Res. Treat. 74:2002;255-269
25. Reis F.M., Cobellis L., Tameirao L.C., Anania G., Luisi S., Silva I.S., Gioffre W., Di Blasio A.M., Petraglia F. Serum and tissue expression of activin A in postmenopausal women with breast cancer. J. Clin. Endocrinol. Metab. 87:2002;2277-2282
26. Robertson D.M., Stephenson T., Pruysers E., McCloud P., Tsigos A., Groome N., Mamers P., Burger H.G. Characterization of inhibin forms and their measurement by an inhibin alpha-subunit ELISA in serum from postmenopausal women with ovarian cancer. J. Clin. Endocrinol. Metab. 87:2002;816-824
27. Robinson G.W., Hennighausen L. Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions. Development. 124:1997;2701-2708
28. Russo I.H., Russo J. Hormonal approach to breast cancer prevention. J. Cell Biochem. Suppl. 34:2000;1-6
29. Silver H.M., Lambert-Messerlian G.M., Reis F.M., Di Blasio A.M., Petraglia F., Canick J.A. Mechanism of increased maternal serum total activin a and inhibin a in preeclampsia. J. Soc. Gynecol. Invest. 9:2002;308-312
30. Welt C.K., Crowley W.F. Jr. Activin: an endocrine or paracrine agent? Eur. J. Endocrinol. 139(469-471):1998;469-471
31. Ying S.Y., Zhang Z. Expression and localization of inhibin/activin subunits and activin receptors in MCF-7 cells, a human breast cancer cell line. Breast Cancer Res. Treat. 37:1996;151-160
32. Yokomuro S., Tsuji H., Lunz J.G. III, Sakamoto T., Ezure T., Murase N., Demetris A.J. Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells. Hepatology. 32:2000;26-35