Activin a exerts both pro- and anti-inflammatory effects on human term gestational tissues

Placenta

Volumn 21, Issue 1, 2000, Pages 38-43

  Keelan, J A ^a   Zhou, R L ^a   Mitchell, M D ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

AMNION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CESAREAN SECTION; DECIDUA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOASSAY; PLACENTA; PRIORITY JOURNAL;

EID: 0033969206     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1053/plac.1999.0451     Document Type: Article

References (52)

1. Benyo D.F., Miles T.M., Conrad K.P. Hypoxia stimulates cytokine production by villous explants from the human placenta. J Clin Endocrinol Metabol. 82:1997;1582-1588.
2. Calogera A.E., Burrello N., Ossino A.M., Polosa P., D'Agata R. Activin-A stimulates hypothalamic gonadotrophin-releasing hormone release by the explanted male rat hypothalamus: interaction with inhibin and androgens. J Endocrinol. 156:1998;269-274.
3. Caniggia I., Lye S.J., Cross J.C. Activin is a local regulator of human cytotrophoblast cell differentiation. Endocrinology. 138:1997;3976-3986.
4. Chen H-L, Yang Y., Hu X-L, Yelavarthi K.K., Fishback J.L., Hunt J.S. Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestation. Am J Pathol. 139:1991;327-335.
5. Conrad K.P., Benyo D.F. Placental cytokines and the pathogenesis of preeclampsia. Am J Reprod Immunol. 37:1998;240-249.
6. de Kretser D.M., Foulds L.M., Hancock M., Robertson D.M. Partial characterization of inhibin, activin, and follistatin in the term human placenta. J Clin Endocrinol Metab. 79:1994;502-507.
7. Dudley D.J. Pre-term labor: an intra-uterine inflammatory response syndrome? J Reprod Immunol. 36:1997;93-109.
8. Fowler P.A., Evans L.W., Groome N.P., Templeton A., Knight P.G. A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alpha C and follistatin during pregnancy. Hum Reprod. 13:1998;3530-3536.
9. Florio P., Lombardo M., Gallo R., Di Carlo C., Sutton S., Genazzani A.R., Petraglia F. Activin A, corticotropin-releasing factor and prostaglandin F2 alpha increase immunoreactive oxytocin release from cultured human placental cells. Placenta. 17:1996;307-311.
10. Goodwin V.J., Sato T.A., Mitchell M.D., Keelan J.A. Anti-inflammatory effects of interleukin-4 interleukin-10, and transforming growth factor-β on human placental cells in vitro. Am J Reprod Immunol. 40:1998;319-325.
11. Hubner G., Brauchle M., Gregor M., Werner S. Activin A: a novel player and inflammatory marker in inflammatory bowel disease? Lab Invest. 77:1997;311-318.
12. Hubner G., Werner S. Serum growth factors and proinflammatory cytokines are potent inducers of activin expression in cultured fibroblasts and keratinocytes. Exp Cell Res. 228:1996;106-113.
13. Keelan J.A., Coleman M., Mitchell M.D. The molecular mechanisms of term and preterm labor: recent progress and clinical implications. Clin Obstet Gynecol. 40:1997;460-478.
14. Keelan J.A., Sato T., Mitchell M.D. Interleukin (IL)-6 and IL-8 production by human amnion - regulation by cytokines, growth factors, glucocorticoids, phorbol esters, and bacterial lipopolysaccharide. Biol Reprod. 57:1997;1438-1444.
15. Keelan J.A., Mitchell M.D. The Effects of a ceramide analogue, N-acetylsphingosine, on basal and tumor necrosis factor-α-stimulated production of prostaglandins and cytokines in gestational tissues. Prostaglandins Other Lipid Mediat. 55:1998;141-158.
16. Keelan J.A., Groome N.P., Mitchell M.D. Tissue concentrations of activin A and interleukins-1β and -8 in human amnion, choriodecidua and placenta before and after labor. J Endocrinol. 156:1998a;P247.
17. Keelan J.A., Groome N.P., Mitchell M.D. Regulation of activin-A production by human amnion, decidua and placenta in vitro by pro-inflammatory cytokines. Placenta. 19:1998b;429-434.
18. Keelan J.A., Simpson K.L., Evans L., Groome N.P., Mitchell M.D. Coordinate regulation of activin-A, inhibin-A and follistatin production in amnion explants by pro-inflammatory cytokines. J Soc Gynecol Invest. 6:1999;203A.
19. Kolodziejczk S.M., Hall B.K. Signal transduction and the TGF-β superfamily receptors. Biochem Cell Biol. 74:1996;299-314.
20. Laham N., Brennecke S.P., Bendtzen K., Rice G.E. Differential release of interleukin-6 from human gestational tissues in association with labour and in vitro endotoxin treatment. J Endocrinol. 149:1996;431-439.
21. Mather J.P., Woodruff T.K., Krummen L.A. Paracrine regulation of reproductive function by inhibin and activin. Proc Soc Exp Biol Med. 201:1992;1-15.
22. Minami S., Yamoto M., Nakano R. Immunohistochemical localization of inhibin/activin subunits in human placenta. Obstet Gynecol. 80:1992;410-414.
23. Muttukrishna S., Fowler P.A., George L., Groome N.P., Knight P.G. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab. 81:1996;3328-3334.
24. Muttukrishna S., Knight P.G., Groome N.P., Redman C.W., Ledger W.L. Activin A and inhibin A as possible endocrine markers for pre-eclampsia. Lancet. 349:1997;1285-1288.
25. Nusing R.M., Mohr S., Ullrich V. Activin A and retinoic acid synergize in cyclooxygenase-1 and thromboxane synthase induction during differentiation of J774.1 macrophages. Eur J Biochem. 227:1995;130-136.
26. O'Connor A.E., McFarlane J.R., Hayward S., Yohkaichiya T., Groome N.P., de Kretser D.M. Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study. Hum Reprod. 14:1999;827-832.
27. Olson D.M., Skinner K., Challis J.R. Prostaglandin output in relation to parturition by cells dispersed from human intrauterine tissues. J Clin Endocrinol Metab. 57:1983;694-699.
28. Peng C., Huang T.H., Jeung E.B., Donaldson C.J., Vale W.W., Leung P.C. Expression of the type II activin receptor gene in the human placenta. Endocrinol. 133:1993;3046-3049.
29. Petraglia F. Inhibin, activin and follistatin in the human placenta - a new family of regulatory proteins. Placenta. 18:1997;3-8.
30. Petraglia F., Vaughan J., Vale W. Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells. Proc Nat Acad Sci U S A. 86:1989;5114-5117.
31. Petraglia F., Woodruff T.K., Botticelli G., Botticelli A., Genazzani A.R., Mayo K.E., Vale W. Gonadotropin-releasing hormone, inhibin, and activin in human placenta: evidence for a common cellular localization. J Clin Endocrinol Metab. 74:1992;1184-1188.
32. Petraglia F., Anceschi M.M., Calza L., Garuti G.C., Fusaro P., Giardino L., Genazzani A.R., Vale W. Inhibin and activin in human fetal membranes: evidence for a local effect on prostaglandin release. J Clin Endocrinol Metab. 77:1993;542-548.
33. Petraglia F., Gallinelli A., De Vita D., Lewis K., Mathews L., Vale W. Activin at parturition: changes of maternal serum levels and evidence for binding sites in placenta and fetal membranes. Obstet Gynecol. 84:1994a;278-282.
34. Petraglia F., Gallinelli A., Grande A., Florio P., Ferrari S., Genazzani A.R., Ling N., DePaolo L.V. Local production and action of follistatin in human placenta. J Clin Endocrinol Metab. 78:1994b;205-210.
35. Petraglia F., Aguzzoli L., Gallinelli A., Florio P., Zonca M., Benedetto C., Woodruff K. Hypertension in pregnancy: changes in activin A maternal serum concentration. Placenta. 16:1995a;447-454.
36. Petraglia F., De Vita D., Gallinelli A., Aguzzoli L., Genazzani A.R., Romero R., Woodruff T.K. Abnormal concentration of maternal serum activin-A in gestational diseases. J Clin Endocrinol Metab. 80:1995b;558-561.
37. Petraglia F., Di Blasio A.M., Florio P., Gallo R., Genazzani A.R., Woodruff T.K., Vale W. High levels of fetal membrane activin beta A and activin receptor IIB mRNAs and augmented concentration of amniotic fluid activin A in women in term or preterm labour. J Endocrinol. 154:1997;95-101.
38. Petraglia F., Santuz M., Florio P., Simoncini T., Luisi S., Plaino L., Genazzani A.R., Genazzani A.D., Volpe A. Paracrine regulation of human placenta - control of hormonogenesis. J Reprod Immunol. 39:1998;221-233.
39. Redinbaugh M.G., Turley R.B. Adaption of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractions. Anal Biochem. 153:1986;267-261.
40. Riley S.C., Balfour C., Wathen N.C., Chard T., Evans L.W., Groome N.P., Wallace E.M. Follistatin and activin A in extra-embryonic coelomic and amniotic fluids and maternal serum in early pregnancy. Hum Reprod. 13:1998;2624-2628.
41. Russell C.E., Hedger M.P., Brauman J.N., de Kretser D.M., Phillips D.J. Activin A regulates growth and acute phase proteins in the human liver cell line, HepG2. Mol Cell Endocrinol. 148:1999;129-136.
42. Shinozaki H., Minegishi T., Nakamura K., Tano M., Miyamoto K., Ibuki Y. Type II and type IIB activin receptors in human placenta. Life Sciences. 56:1995;1699-1706.
43. Simpson K.L., Keelan J.A., Mitchell M.D. Labor-associated changes in the regulation of production of immunomodulators in human choriodecidua. J Clin Endocrinol Metab. 83:1998;4332-4337.
44. Simpson K.L., Keelan J.A., Mitchell M.D. Labour-associated changes in interleukin-10 production and its regulation by immunomodulators in human amnion by glucocorticoids, bacterial lipopolysaccharide and pro-inflammatory cytokines. J Reprod Fertil. 116:1999a;321-327.
45. Simpson K.L., Keelan J.A., Mitchell M.D. The anti-inflammatory cytokine interleukin-10 has pro-inflammatory effects on human amnion. J Soc Gynecol Invest. 6:1999b;202A.
46. Song Y., Keelan J., France J.T. Activin-A stimulates, while transforming growth factor beta 1 inhibits, chorionic gonadotrophin production and aromatase activity in cultured human placental trophoblasts. Placenta. 17:1996;603-610.
47. Wang Y.P., Walsh S.W. TNF-α concentrations and mRNA expression are increased in preeclamptic placentas. J Reprod Immunol. 32:1996;157-163.
48. Welt C.K., Crowley W.F. Jr. Activin: an endocrine or paracrine agent. Eur J Endocrinol. 139:1998;469-471.
49. Yu E.W., Dolter K.E., Shao L.E., Yu J. Suppression of IL-6 biological activities by activin A and implications for inflammatory arthropathies. Clin Exp Immunol. 112:1998;126-132.
50. Yu J., Dolter K.E. Production of activin A and its roles in inflammation and hematopoiesis. Cytokines, Cell Mol Ther. 3:1997;169-177.
51. Yu J., Shao L.E., Frigon N.L. Jr, Lofgren J., Schwall R. Induced expression of the new cytokine, activin A, in human monocytes: inhibition by glucocorticoids and retinoic acid. Immunology. 88:1996;368-374.
52. Yui J., Garcia-Lloret M., Wegmann T.G., Guilbert L.J. Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta. 15:1994;819-835.