Protective effect of N-acetyl-serotonin on the nonenzymatic lipid peroxidation in rat testicular microsomes and mitochondria

Journal of Pineal Research

Volumn 37, Issue 3, 2004, Pages 153-160

  Gavazza, Mariana B ^a   Català, Angel ^a,b  

^a FACULTAD DE CIENCIAS VETERINARIAS   (Argentina)

^b Consejo Nac Invest Cie Y Tec R ^*  (Argentina)

Author keywords

Lipid peroxidation; Microsomes; Mitochondria; N acetyl serotonin; Testis

Indexed keywords

FERROUS ASCORBATE; N ACETYLSEROTONIN; POLYUNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CELL ORGANELLE; CHEMOLUMINESCENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; IC 50; LIPID COMPOSITION; LIPID PEROXIDATION; MALE; MICROSOME; MICROSOME MEMBRANE; MITOCHONDRIAL MEMBRANE; NONHUMAN; RAT; TESTIS;

ANIMALS; ARACHIDONIC ACID; ASCORBIC ACID; CHEMILUMINESCENT MEASUREMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYMES; FATTY ACIDS, UNSATURATED; INHIBITORY CONCENTRATION 50; INTRACELLULAR MEMBRANES; LIPID PEROXIDATION; MALE; MICROSOMES; MITOCHONDRIA; OXIDATIVE STRESS; PROTECTIVE AGENTS; RATS; RATS, WISTAR; SEROTONIN; TESTIS;

EID: 4644225110     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2004.00150.x     Document Type: Article

References (43)

1. TAN DX, CHEN LD, POEGGELER B et al. Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr 1993; 1:57-60.
2. POEGGELER B, REITER RJ, HANDERLAND R et al. Melatonin and structurally-related, endogenous indoles act as a potent electron donors and radical scavengers in vitro. Redox Rep 1996; 2:179-184.
3. PLESS G, FREDERIKSEN TJP, GARCÏA JJ et al. Pharmacological aspects of N-acetyl-5-methxytryptamine (melatonin) and 6-methoxy-1,2,3,4-tetrahydro-B- carboline (pinoline) as antioxidants reduction of oxidative damage in brain region homogenates. J Pineal Res 1999; 26:236-246.
4. 2: protection by melatonin and related molecules. J Pineal Res 2000; 29:54-61.
5. ITOH MT, ISHIZUKA B, KUDO Y et al. Detection of melatonin and serotonin N-acetyltransferase and hydroxyindole-O-methyltransferase activities in rat ovary. Mol Cell Endocrinol 1997; 136:7-13.
6. PANG SF, TANG F, TANG PL. Negative correlation of age and the levels of pineal melatonin, pineal N-acetylserotonin, and serum melatonin in male rats. J Exp Zool 1984; 229:41-47.
7. MIGUEZ JM, RECIO J, SANCHEZ-BARCELO E et al. Changes with age in daytime and nighttime contents of melatonin, indolamines, and catecholamines in the pineal gland: a comparative study in rat and Sirian hamster. J Pineal Res 1998; 25:106-115.
8. BACHURIN S, OXENKRUG G, LERMONTOVA N et al. N-acetylserotonin, melatonin and their derivativesbimprove cognition and protect against B-amyloid- induced neurotoxicity. Ann NY Acad Sci 1999; 890:155-166.
9. LOPEZ-GONZALEZ MA, GUERRERO JM, TORRONTERAS R et al. Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs. J Pineal Res 2000; 28:26-33.
10. OHTA Y, KONGO M, SASAKI E et al. Therapeutic effect of melatonin on carbon tetrachloride-induced acute liver injury in rats. J Pineal Res 2000; 28:119-126.
11. MONTILLA P, TUNEZ L, MUNOZ DE AGUEDA MC et al. Protective effect of meiatonin against oxidative stress induced by ligadure of extra-hepatic biliary duct in rats: comparison with the effect of S-adenosyl-L-methionine. J Pineal Res 2000; 28:143-149.
12. MARTIN M, MACIAS M, ESCAMES G et al. Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo. J Pineal Res 2000; 28:242-248.
13. CALVO JR, REITER RJ, GARCÏA JJ et al. Characterization of the protective effects of melatonin and related indoles against α- naphthylisothiocyanate-induced liver injury in rats. J Cell Biochem 2001; 80:461-470.
14. HARMAN D. Free radical theory of aging: the free radical disease. Age 1984; 7:111-131.
15. VIANI P, CERVATO G, FIORILLI A et al. Age-related differences in synaptosomal peroxidative damage and membrane properties. J Neurochem 1991; 56:253-258.
16. 2: modulation by dietary restriction. Mech Ageing Dev 1992; 65:17-33.
17. CHOE M, JACKSON C, YU BP. Lipid peroxidation contributes to age-related membrane rigidity. Free Radic Biol Med 1995; 18:977-984.
18. REITER RJ, TAN DX, KIM SJ et al. Augmentation of indices of oxidative damage in life-long-melatonin-deficient rats. Mech Ageing Dev 1999; 110:157-173.
19. LEE J, Yu BP, HERLIHY JT. Modulation of cardiac mitochondrial membrane fluidity by age and calorie intake. Free Radic Biol Med 1999; 26:260-265.
20. HASHIMOTO M, HOSSAIN S, MASUMURA S. Effect of aging on plasma membrane fluidity of rat aortic endothelial cells. Exp Gerontol 1999; 34:687-698.
21. KANFER JN, SORRENTINO G, SITARDS Amyloid beta peptide membrane perturbation is the basis for its biological effects. Neurochem Res 1999; 24:1621-1630.
22. + ATPase. Eur J Biochem 2000; 267:2071-2078.
23. +2 peroxidation of rat testis microsomes and mitochondria. Int J Biochem Cell Biol 2003; 35:359-366.
24. SCHNEIDER WC, KUFF EL. The association of deoxyribonucleic acid with liver microsomes. J Biol Chem 1969; 244:4843-4851.
25. CATALA A. Interaction of fatty acids, acyl-CoA derivatives and retinoids with microsomal membranes: effect of cytosolic proteins. Mol Cell Biochem 1993; 120:89-94.
26. WRIGHT JR, RUMBAUGH RC, COLBY HD et al. The relationship between chemiluminescence and lipid peroxidation in rat hepatic microsomes. Arch Biochem Biophys 1979; 192:344-351.
27. RODA A, PASINI P, GUARDIGLI M et al. Bio and chemiluminescence in bioanalysis. Fresenius J Anal Chem 2000; 366:752-759.
28. FOLCH J, LEES N, SLOANE-STANLEY GA. A simple methods for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226:497-509.
29. HOLMAN TR. Autoxidation of fats and related substances. In: Progress in the Chemistry of Fats an Other Lipids. Holman R, Lundberg WO, Malkin T eds. Academic Press, New York, 1954, pp. 491-514.
30. LOWRY OH, ROSEBROUGHT NJ, FARR AL et al. Protein measurement with Folin phenol reagent. J Biol Chem 1951; 193:265-275.
31. SNEDECOR GW, COCHRAN WG. Statistical Methods. Univ Press, Ames, pp. 120-134.
32. GARCÏA JJ, REITER RJ, KARBOWNIK M et al. N-acetylserotonin suppresses hepatic microsomal membrane rigidity associated with lipid peroxidation. Eur J Pharmacol 2001; 428:169-175.
33. CHAN TY, TANG PL. Characterization of the antioxidant effects of melatonin and related indoleamine in vitro. J Pineal Res 1996; 20:187-191.
34. LONGONI B, PRYOR WA, MARCHIAFAVA P. Inhibition of lipid peroxidation by N-acetyl-serotonin and its role in retinal physiology. Biochem Biophys Res Commun 1997; 233: 778-780.
35. LEZOUALC'H F, SPARAPANI M, BEHL C. N-acetyl-serotonin (normomelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the trancription factor NF-κB. J Pineal Res 1998; 24:168-178.
36. SIU AW, REITER RJ, TO CH. Pineal indolamines and vitamin E reduce nitric oxide-induced lipid peroxidation in rat retinal homogenates. J Pineal Res 1999; 27:122-128.
37. SEEGER H, MUECK AO, LIPPERT TH. Effect of melatonin and metabolites on copper-mediated oxidation of low density lipoprotein. Br J Clin Pharmacol 1997; 44:283-284.
38. GOZZO A, LESIEUR D, DURIEZ P et al. Structure-activity relationships in a series of melatonin analogues with the low-density lipoprotein oxidation model. Free Radic Biol Med 1999; 26:1538-1543.
39. SIEU AW, CHEUNG JP, TO CH et al. N-acetyl-serotonin reduces copper (I) iron-induced lipid peroxidation in bovine retinal homogenates. Acta Ophthalmol Scand 2001; 79:69-71.
40. REITER RJ, TAN DX, CABRERA J et al. Melatonin and tryptophan derivatives as free radical scavengers and antioxidants. Adv Exp Med Biol 1999; 467:379-387.
41. DANIELS WMU, VAN RENSBURG SJ, VAN ZYL JM et al. Free radical scavenging effects of melatonin and serotonin: posible mechanism. Neuroreport 1996; 7:1593-1596.
42. KARBOWNIK M, GITTO E, LEWINSKI A et al. Relative efficacies of indole antioxidants in reducing autoxidation and iron-induced lipid peroxidation in hamsters testis. J Cell Biochem 2001; 81:693-699.
43. MONTILLA P, CRUZ A, PADILLO FJ et al. Melatonin versus vitamin E as protective treatment against oxidative stress after extra-hepatic bile duct ligation in rats. J Pineal Res 2001; 31:138-144.