Characterization of the antioxidant effects of melatonin and related indoleamines in vitro

Journal of Pineal Research

Volumn 20, Issue 4, 1996, Pages 187-191

  Chan, Tak Yuen ^a   Tang, Pak Lai ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Antioxidant; Free radicals; Indoleamine; Lipid peroxidation; Melatonin

Indexed keywords

ANTIOXIDANT; DRUG DERIVATIVE; FREE RADICAL; LIPOSOME; MELATONIN; PHOSPHOLIPID; SEROTONIN; SUPEROXIDE; TRYPTOPHAN;

ANIMAL; ARTICLE; DNA DAMAGE; DRUG EFFECT; ERYTHROCYTE MEMBRANE; LIPID PEROXIDATION; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; DNA DAMAGE; ERYTHROCYTE MEMBRANE; FREE RADICALS; LIPID PEROXIDATION; LIPOSOMES; MELATONIN; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SUPEROXIDES; TRYPTOPHAN;

EID: 0030136182     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-079X.1996.tb00257.x     Document Type: Article

References (20)

1. AESCHBACH, R., J. LÖLIGER, B.C. SCOTT, A. MURCIA, J. BUTLER, B. HALLIWELL, O.I. ARUOMA (1994) Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol. Food Chem. Toxicol. 32:31-36.
2. ARUOMA, O.I., B. HALLIWELL, B.M. HOEY, J. BUTLER (1988) The antioxidant action of taurine, hypotaurine and their metabolic precursors. Biochem J. 256:251-255.
3. BARLOW-WALDEN, L.R., R.J. REITER, M. ABE, M. PABLOS, A. MENENDEZ-PELAEZ, L.D. CHEN, B. POEGGELER (1995) Melatonin stimulates brain glutathione peroxidase activity. Neurochem. Int. 26:497-502.
4. CAGNOLI, C.M., C. ATABAY, E. KHARLAMOVA, H. MANEV (1995) Melatonin protects neurons from singlet oxygen-induced apoptosis. J. Pineal Res. 18:222-226.
5. IANAS, O., R. OLNESCU, I. BADESCU (1991) Melatonin involvement in oxidative processes. Rom. Endocrinol. 29:147-153.
6. LAPENNA, D., S. DE GIOIA, G. CIOFANI, F. CUCCURULLO (1994) Ambroxol is a scavenger of hypochlorous acid and monochloramine. Pharmacology 49:132-135.
7. MELCHIORRI, D., R.J. REITER, E. SEWERYNEK, L.D. CHEN, G. NISTICO (1995) Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. FASEB J. 9:1205-1210.
8. MENENDEZ-PELAEZ, A., B. POEGGELER, R.J. REITER, L. BARLOW-WALDEN, M.I. PABLOS, D.X. TAN (1993) Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence. J. Cell. Biochem. 53:373-382.
9. MISRA, H.P., I. FRIDOVICH (1972) The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247:3170-3175.
10. MORREY, K.M., J.A. MCLACHLAN, C.D. SHERKIN, O. BAKOUCHE (1994) Activation of human monocytes by the pineal hormone melatonin. J. Immunol. 153:2671-2680.
11. PEREZ-REYES, E., R.P. MASON (1981) Characterization of the structure and reactions of free radicals from serotonin and related indoles. J. Biol. Chem. 256:2427-2432.
12. PIERI, C., M. MARRA, F. MORONI, R. RECCHIONI, F. MARCHESELLI (1994) Melatonin: A peroxyl radical scavenger more effective than vitamin E. Life Sci. 55:PL271-276.
13. POEGGELER, B., R.J. REITER, R. HARDELAND, E. SEWERYNEK, D. MELCHIORRI, L.R. BARLOW-WALDEN (1995) Melatonin, a mediator of electron transfer and repair reactions, acts synergistically with the chain-breaking antioxidants ascorbate, trolox and glutathione. Neuroendocrinol. Lett. 17:87-92.
14. QUINLAN, G.J., B. HALLIWELL, C.P. MOORHOUSE, J.M.C. GUTTERIDGE (1988) Action of lead(II) and aluminum(III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and rat liver microsomal fractions. Biochim. Biophys. Acta 962:196-200.
15. REITER, R.J., D. MELCHIORRI, E. SEWERYNEK, B. POEGGELER, L. BARLOW-WALDEN, J. CHUANG, G.G. ORTIZ, D. ACUÑA-CASTROVIEJO (1995) A review of the evidence supporting melatonin's role as an antioxidant. J. Pineal Res. 18:1-11.
16. 2-induced lipid peroxidation in rat brain homogenates is greatly reduced by melatonin. Neurosci. Lett. 195:203-205.
17. SEWERYNEK, E., D. MELCHIORRI, L.D. CHEN, R.J. REITER (1995b) Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro. Free Rad. Biol. Med. 19:903-909.
18. SEWERYNEK, E., D. MELCHIORRI, R.J. REITER, G. ORTIZ, A. LEWINSKI (1995c) Lipopolysaccharide-induced hepatotoxicity is inhibited by the antioxidant melatonin. Eur. J. Pharmacol. 293:327-334.
19. SHIDA, C.S., A.M.L. CASTRUCCI, M.T. LAMY-FREUND (1994) High melatonin solubility in aqueous medium. J. Pineal Res. 16:198-201.
20. TAN, D.X., L.D. CHEN, B. POEGGELER, L.C. MANCHESTER, R.J. REITER (1993) Melatonin: A potent, endogenous hydroxyl radical scavenger. Endocrine J. 1:57-60.