Melatonin versus vitamin E as protective treatment against oxidative stress after extra-hepatic bile duct ligation in rats

Journal of Pineal Research

Volumn 31, Issue 2, 2001, Pages 138-144

  Montilla, P ^a,b   Cruz, A ^a   Padillo, F J ^a   Tunez I ^a   Gascon, F ^a   Munoz M C ^a   Gomez M ^a   Pera, C ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b Facultad de Medicina de Córdoba   (Spain)

Author keywords

Free radicals; Melatonin; Obstructive jaundice; Vitamin E

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOCHEMICAL MARKER; FREE RADICAL; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; MALONALDEHYDE; MELATONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BLOOD LEVEL; CHOLESTASIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; EVALUATION; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TISSUE LEVEL;

ANIMALS; ANTIOXIDANTS; BILE DUCTS, EXTRAHEPATIC; CHOLESTASIS; LIGATION; LIPID PEROXIDATION; LIVER; MALE; MELATONIN; OXIDATIVE STRESS; RATS; RATS, WISTAR; VITAMIN E;

EID: 0034894080     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079X.2001.310207.x     Document Type: Article

References (55)

1. Reversibility of hepatic fibrosis in experimentally induced cholestasis in rat
2. Catalase in vitro
3. Role of S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis
4. Ligation of the common bile duct
5. Cytoprotective effects of alpha tocopherol against liver injury induced by extrahepatic biliary obstruction
6. Vitamin A inhibits doxorubicin-induced membrane lipid peroxidation in rat tissues in vivo
7. Bile and bile salts potentiate superoxide anion release from activated rat peritoneal neutrophils
8. Regulation of cholesterol and bile acid homeostasis in bile-obstructed rats
9. Assays of glutathione peroxidase
10. Sodium coupled ion electrolyte transport across ephithelia: Emerging concepts and directions
11. Clinical-experimental bases of the use antioxidants in the treatment of mechanical jaundice
12. Effects of S-adenosyl-1-methionine on hepatic and renal oxidative stress in an experimental model of acute biliary obstruction in rats
13. Suppresion of cellular inmunity in obstructive jaundice is caused by endotoxins: A study with germ-free rats
14. Glutathione and glutathione disulphide
15. Oxigen free radicals and iron in relation to biology and medicine. Some problems and concepts
16. Oxidants and human disease: Some new concepts
17. Antioxidants and human disease: A general introduction
18. Prolonged bile duct obstruction: A new experimental model for cirrhosis in rat
19. Toxicity of bile acids on electron transport chain of isolate rat liver mitochondria
20. Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats
21. Free radicals: Their involvement in disease processes
22. Vitamin E
23. Hyperlipidemic nephropathy induced by adriamycin: Effect of melatonin administration
24. Antioxidative effect of melatonin in rat brain oxidative stress induced by adriamycin
25. Protective role of melatonin and retinol palmitate in oxidative stress and hyperlipidemic nephrophaty induced by adriamycin in rats
26. Oxidative stress in diabetic rats induced by streptozotocin: Protective effects of melatonin
27. Protective effect of melatonon agains oxidative stress induced by ligature of extra-hepatic biliary duct in rats: Comparison with the effect of S-adenosyl-L-methionine
28. Role of lipid peroxidation in biliary obstruction in the rat
29. Protective effect of melatonin against α-naphthylisothiocyanate induced liver injury in rats
30. Therapeutic effect of melatonin on carbon tetrachloride induced acute liver injury in rats
31. Changes in the pattern of visceral proteins after internal biliary drainage in patients with obstructive jaundice
32. Antioxidant enzyme status in biliary obstructed rats: Effects of N-acetylcysteine
33. Melatonin-A highly potent endougenous radical scavenger and electron donor: New aspects of the oxidation chemistry of this indole assessed in vitro
34. Melatonin and structurally-related endogenous indoles act as potent electron donors and free radical scavenger
35. Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum
36. Antioxidant actions of melatonin
37. Aging and oxigen toxicity: Relation to changes in melatonin
38. Oxidative damage in the central nervous system: Protection by melatonin
39. Antioxidant capacity of melatonin: A novel action not requiring a receptor
40. Pharmacological actions of melatonin in free radical pathophysiology
41. Involvement of oxygen radicals in bile acid-induced hepatocytes injury
42. Antioxidant defenses in the bile duct-ligated rat
43. Overview: The Na, K-pump
44. Treatment of cholestatic children with water-soluble vitamin E (α-tocopheryl polyethylene glycol succinate): Effects on serum vitamin E, lipid peroxides and polyunsaturated fatty acids
45. Correction of vitamin E deficiency in children with choronic cholestasis. II. Effect on gastrointestinal and hepatic function
46. Effect of dietary lipid and vitamin E on mitochondrial lipid peroxidation and hepatic injury in the bile duct-ligated rats
47. Multicenter trial of alfa-tocopheryl polyethylene glycol 1000 succinate for treatement of vitamina E deficiency in children with chronic cholestasis
48. Evidence for involvement of oxygen free radicals in the bile acid toxicity to isolated rat hepatocytes
49. Generation of hydroperoxides in isolated rate hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids
50. The nuclear receptor of melatonin repressess 5-lipoxygenase gene expression in human B lymphocytes
51. A simple method for clinical assay of superoxide dismutase
52. Melatonin: A potent endogenous hydroxyl radical scavenger
53. High physiological levels of melatonin in bile of mammals
54. Activities of free oxygen radical scavenger enzymes in human liver
55. Glutathione transferases from human liver