Relative efficacies of indole antioxidants in reducing autoxidation and iron-induced lipid peroxidation in hamster testes

Journal of Cellular Biochemistry

Volumn 81, Issue 4, 2001, Pages 693-699

  Karbownik, Malgorzata ^a   Gitto, Eloisa ^b   Lewiñski, Andrzej ^a   Reiter, Russel J ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Cancer; Indoles; Iron; Lipid peroxidation; Melatonin; Testes

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; ANTINEOPLASTIC AGENT; ANTIOXIDANT; FERROUS SULFATE; HYDROGEN PEROXIDE; INDOLE DERIVATIVE; INDOLEPROPIONIC ACID; IRON; MALONALDEHYDE; MELATONIN; N ACETYLSEROTONIN;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; HAMSTER; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TESTIS CANCER; TISSUE HOMOGENATE;

ANIMALS; ANTIOXIDANTS; CRICETINAE; HYDROXYINDOLEACETIC ACID; INDOLES; IRON; LIPID PEROXIDATION; MALE; MELATONIN; MESOCRICETUS; OXIDATION-REDUCTION; PROPIONIC ACIDS; SEROTONIN; TESTICULAR NEOPLASMS; TESTIS;

EID: 0035004486     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.1100     Document Type: Article

References (50)

1. Protective effect of melatonin against 1-methyl-4-phenylpyridinium-induced inhibition of Complex I of the mitochondrial respiratory chain
2. Melatonin, mitochondria and cellular bioenergetics
3. Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa
4. On the antioxidant activity of melatonin
5. Vitamin E consumption induced by oxidative stress in red blood cells is enhanced by melatonin and reduced by N-acetylserotonin
6. Nitrosation of melatonin by nitric oxide and peroxynitrite
7. Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events
8. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
9. Scavenging effect of melatonin on hydroxyl radicals generated by alloxan
10. Genotoxic lipid peroxidation products: Their DNA damaging properties and role in formation of endogenous DNA adducts
11. Characterization of the protective effects of melatonin and related indoles against α-naphthylisothiocyanate-induced liver injury in rats
12. Interactions of melatonin with membrane models: Portioning of melatonin in AOT and lecithin reversed micelles
13. Hydroxyl radical-induced decline in motility and increase in lipid peroxidation and DNA modification in human sperm
14. Potent neuroprotective properties against the Alzheimer β-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid
15. Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration
16. 5-methoxytryptophol preserves hepatic microsomal membrane fluidity during oxidative stress
17. Antioxidative effect of melatonin on human spermatozoa
18. Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts
19. Indole-3-pyruvic and -propionic acids, kynurenic acid, and related metabolites as luminophores and free-radical scavengers
20. Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation
21. Melatonin reduces the oxidation of nuclear DNA and membrane lipids induced by the carcinogen δ-aminolevulinic acid
22. Melatonin reduces rat hepatic macromolecular damage due to oxidative stress caused by δ-aminolevulinic acid
23. Melatonin reduces phenylhydrazine-induced oxidative damage to cellular membranes: Evidence for the involvement of iron
24. Indole-3-propionic acid, a melatonin-related molecule, protects hepatic microsomal membranes from iron-induced oxidative damage: Relevance to cancer reduction
25. Comparison of the protective effect of melatonin with other antioxidants in the hamster kidney model of estradiol-induced DNA damage
26. Oxidative damage to lipids and DNA concurrent with decrease of antioxidants in rat testes after acute iron intoxication
27. Dose-dependent increase of oxidative damage in the testes of rats subjected to acute iron overload
28. Lipid peroxidation-DNA damage by malondialdehyde
29. Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo
30. In vitro influence of ascorbate on lipid peroxidation in rat testis and heart microsomes
31. Neuroprotective potential of aromatic alcohols against oxidative cell death
32. Risk of testicular cancer in subfertile men: Case-control study
33. Melatonin and its precursors scavenge nitric oxide
34. Rhythms of glutathione peroxidase and glutathione reductase in the brain of chick and their inhibition by light
35. Melatonin: A peroxyl radical scavenger more effective than vitamin E
36. Oxygen radicals, melatonin and aging
37. Indole-3-propionate: A potent hydroxyl radical scavenger in rat brain
38. 2: Protection by melatonin and related molecules
39. Antioxidant actions of melatonin
40. Oxidative damage in the central nervous system: Protection by melatonin
41. Oxidative damage to nuclear DNA: Amelioration by melatonin
42. Melatonin: Lowering the high price of free radicals
43. Circadian aspects of the cellular redox state: Melatonin actions and implications for oncogenesis
44. Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo
45. Body iron stores and the risk of cancer
46. Melatonin: A potent, endogenous hydroxyl radical scavenger
47. Melatonin directly scavenges hydrogen peroxide: A new metabolic pathway
48. The clinical and laboratory correlates of an increased urinary 5-hydroxyindoleacetic acid
49. Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 human vascular endothelial cells
50. The role of iron in cancer