Conservation patterns of HIV-1 RT connection and RNase H domains: Identification of new mutations in NRTI-treated patients

PLoS ONE

Volumn 3, Issue 3, 2008, Pages

  Santos, André F A ^a   Lengruber, Renan B ^a   Soares, Esmeralda A ^a   Jere, Abhay ^b   Sprinz, Eduardo ^c   Martinez, Ana M B ^d   Silveira, Jussara ^d   Sion, Fernando S ^e   Pathak, Vinay K ^b   Soares, Marcelo A ^a,f  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b NATIONAL CANCER INSTITUTE   (United States)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

^e HOSPITAL UNIVERSITÁRIO GAFFRÉE E GUINLE   (Brazil)

^f INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEIC ACID; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA; ZIDOVUDINE; PRIMER DNA; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; ARTICLE; BRAZIL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG DESIGN; DRUG EXPOSURE; DRUG TARGETING; ENZYME ACTIVE SITE; FISHER EXACT TEST; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VIVO STUDY; MAJOR CLINICAL STUDY; MONOTHERAPY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SEQUENCE DATABASE; STRAIN DIFFERENCE; VIRUS ISOLATION; VIRUS MUTATION; VIRUS STRAIN; CHEMISTRY; ENZYMOLOGY; GENETICS; MOLECULAR GENETICS; MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; BASE SEQUENCE; CONSERVED SEQUENCE; DNA PRIMERS; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE INHIBITORS; RIBONUCLEASE H; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 46349088795     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001781     Document Type: Article

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