Production of angiotensin I-converting enzyme inhibitor derived from egg white protein hydrolysates using a membrane reactor

Journal of Food and Drug Analysis

Volumn 16, Issue 2, 2008, Pages 54-60

  Chiang, Wen Dee ^a   Tsou, May June ^b   Weng, Chien Hui ^a   Tsai, Tsun Chung ^a  

^a TUNGHAI UNIVERSITY   (Taiwan)

^b CHUNG CHOU INSTITUTE OF TECHNOLOGY   (Taiwan)

Author keywords

ACE inhibitor; Egg white proteins; Hydrolysate; Membrane reactor; Peptide

Indexed keywords

CHYMOTRYPSIN; DIPEPTIDYL CARBOXYPEPTIDASE; EGG PROTEIN; EGG WHITE; PROTEIN HYDROLYSATE; PROTEINASE; SUBTILISIN; THERMOLYSIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; MEMBRANE REACTOR; MOLECULAR WEIGHT; NONHUMAN; PROTEIN HYDROLYSIS; RABBIT; STATISTICAL SIGNIFICANCE;

EID: 46249133973     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Erdos, E. G. 1975. Angiotensin-I converting enzyme. Circ. Res. 36: 247-255.
2. Koike, H., Ito, K., Miyamoto, M. and Nishino, H. 1980. Effects of long-term blockade of angiotensin-converting enzyme with captopril on hemodynamics and circulating blood volume in SHR. Hypertension 2: 229-303.
3. Ariyoshi, Y. 1993. Angiotensin-converting enzyme inhibitors derived from food proteins. Trends Food Sci. Technol. 4: 139-144.
4. Fujita, H., Yokoyama, K. and Yoshikawa, M. 2000. Classification and antihypertensive activity of angiotensin I-converting enzyme inhibitory peptides derived from food protein. J. Food Sci. 65: 564-569.
5. Li, G. H., Le, G. W., Shi, Y. H. and Shrestha, S. 2004. Angiotensin I-converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects. Nutr. Res. 24: 469-486.
6. Miguel, M., Recio, I., Gomez-Ruiz, J. A., Ramos, M. and Lopez-Fandino, R. 2004. Angiotensin I-converting enzyme inhibitory activity of peptides derived from egg white proteins by enzymatic hydrolysis. J. Food Prot. 67: 1914-1920.
7. Yoshii, H., Tachi, N., Ohba, R., Sakamura, O., Takeyama, H. and Itani, T. 2001. Antihypertensive effect of ACE inhibitory oligopeptides from chicken egg yolks. Comp. Biochem. Physiol. C 128: 27-33.
8. Adler-Nissen, J. 1986. Methods in food protein hydrolysates. In "Enzymatic Hydrolysis of Food Protein". pp. 110-131. Hudson, B. J. F. ed. Elsevier Applied Science. New York, U. S. A.
9. Cheftel, C., Ahern, M., Wang, D. I. C and Tannenbaum, S. R. 1971. Enzymatic solublization enzyme recycling processes. J. Agri. Food Chem. 19: 155-161.
10. Deeslie, W. D. and Cheryan, M. 1988. Functional properties of soy protein hydrolysates from a continuous ultrafiltration reactor. J. Agri. Food Chem. 36: 26-31.
11. Lin, S. B., Chiang, W. D., Cordle, C. T. and Thomas, R. L. 1997. Functional and immunological properties of casein hydrolysate produced from a two-stage membrane system. J. Food Sci. 62: 480-483.
12. Prendergast, K. 1974. Protein hydrolysates- a review. Food Trade Rev. 44: 16.
13. Xavier, A. M. R. B., Goncalves, L. M. D., Moreira, J. L. and Carrondo, M. J. T. 1995. Operational patterns affecting lactic acid production in ultrafiltration cell recycle bioreactor. Biotechnol. Bioeng. 45: 320-327.
14. Deeslie, W. D. and Cheryan, M. 1981. Continuous enzymatic modification of proteins in an ultrafiltration reactor. J. Food Sci. 46: 1035-1042.
15. Chiang, W. D., Chih, C. J. and Chu, Y. W. 1999. Functional properties of soy protein hydrolysate produced from a continuous membrane reactor system. Food Chem. 65: 189-194.
16. Chiang, W. D., Tsou, M. J., Tsai, Z. Y. and Tsai, T. C. 2006. Angiotensin I-converting enzyme derived from isolated soy protein and produced by using membrane reactor. Food Chem. 98: 725-732.
17. Iacobucci, G. A., Myers, M. J., Emi, S. and Myers, D. V. 1974. Large scale continuous production of soybean protein hydrolysate in a constant flux membrane reactor. Proc. IV Int. Congress Food Sci. Technol. 5: 83-95.
18. Chiang, W. D., Cordle, C. T. and Thomas, R. L. 1995. Casein hydrolysate produced using a formed-in-place membrane reactor. J. Food Sci. 60: 1349-1352.
19. Frister, H., Meisel, H. and Schlimme, E. 1998. OPA Method modified by use of N,N-dimethyl-2-mercaptoehylammonium chlorides as thiol component. Fresenius Z. Anal. Chem. 330: 631-633.
20. Cushman, D. W. and Cheung, H. S. 1971. Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Pharmacol. 20: 1637-1648.
21. AOCS. 1989. Official Methods and Recommended Practices of the American Oil Chemists' Society. 4th ed. Champaign, IL, AOCS.
22. Cheryan, M. and Deeslie, W. D. 1983. Soy protein hydrolysis in membrane reactors. J. Am. Oil Chem. Soc. 60: 1112-1115.
23. Wu, J. and Ding, X. 2002. Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides. Food Res. Int. 35: 367-375.
24. Arihara, K., Nakashima, Y., Mukai, T., Ishikawa, S. and Itoh, M. Peptide inhibitors for angiotensin I-converting enzyme from enzymatic hydrolysates of porcine skeletal muscle proteins. Meat Sci. 57: 319-324.
25. Hernandez-Ledesma, B., Recio, I., Ramos, M. and Amigo, L. 2002. Preparation of ovine and caprine beta-lactoglobulin hydrolysates with ACE-inhibitory activity, identification of active peptides from caprine beta-lactoglobulin hydrolysed with thermolysin. Int. Dairy J. 12: 805-812.
26. Yokoyama, K., Chiba, H. and Yoshikawa, M. 1992. Peptide inhibitor for angiotensin I-converting enzyme from:thermolysin digest of dried bonito. Biosci. Biotechnol. Biochem. 56: 1541-1545.
27. Karaki, H., Doi, K., Sugano, S., Uchiwa, H., Sugai, R., Murakami, U. and Takemoto, S. 1990. Antihypertensive effect of tryptic hydrolysate of milk casein in spontaneously hypertensive rats. Comp. Biochem. Physiol. 96 C2: 367-371.
28. Mullally, M. M., Meisel, H. and Fitzgerald, R. J. 1996. Synthetic peptides corresponding to α-lactalbumin and β-lactoglobulin sequences with angitensin I-converting enzyme inhibitory activity. Biol. Chem. Hoppe-Seyler 377: 259-260.
29. Matsui, T., Yukiyoshi, A., Doi, S., Sugimoto, H. and Yamada, H. 2002. Gastrointestinal enzyme production of bioactive peptides from royal jelly protein and their antihypertensive ability in SHR. J. Nutr. Biochem. 13: 80-86.
30. Mannhein, A. and Cheryan, M. 1990. Continuous hydrolysis of milk protein in a membrane reactor. J. Food Sci. 55: 381-385, 390.
31. Grimble, G. K., Rees, R. G., Keohane, P. P., Cartwright, T., Desreumaux, M. and Silk, D. B. 1987. Effect of peptide chain length on absorption of egg protein hydrolysates in the normal human jejunum. Gastroenterology 92: 136-142.