Glycine decreases developmental damage induced by hyperglycaemia in mouse embryos

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 7, 2008, Pages 895-900

  Martinez Galero E ^a   Paniagua Castro, N ^a   Perez Pasten R ^a   Madrigal Bujaidar, E ^a   Chamorro Cevallos, G ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM; CONTROLLED STUDY; CULTURE MEDIUM; DNA CONTENT; DRUG EFFECT; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO GROWTH; EMBRYOPATHY; HYPERGLYCEMIA; LIPID PEROXIDATION; MORPHOGENESIS; MOUSE; NONHUMAN; SERUM; SOMITE; TELENCEPHALON; TERATOGENESIS;

ANIMALS; CONGENITAL ABNORMALITIES; FEMALE; FETAL GROWTH RETARDATION; GLYCINE; HYPERGLYCEMIA; LIPID PEROXIDATION; MALE; MICE; NEURAL TUBE DEFECTS; ORGAN CULTURE TECHNIQUES; PREGNANCY;

EID: 46249120191     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.60.7.0011     Document Type: Article

References (40)

1. Alvarado-Vásquez, N., Zamudio, P., Cerón, E., Vanda, B., Zenteno, E., Carvajal-Sandoval, G. (2003) Effect of glycine in streptozotocin-induced diabetic rats. Comp. Biochem. Physiol. Part C 134: 521-527
2. +-dependent transporters. Eur. J. Neurosci. 12: 1924-1930
3. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254
4. Brown, N. A., Fabro, S. (1981) Quantitation of rat embryonic development in vitro: a morphological scoring system. Teratology 24: 65-78
5. Buege, J. A., Aust, S. D. (1978) Microsomal lipid peroxidation. In: Fleischer, S., Packer, L. (eds) Biomembranes. Part C. Biological oxidations, microsomal cytochrome P-450, and other hemoprotein systems. Academic Press, San Diego, pp 302-310
6. Carvajal, G., Medina, R., Juarez, E., Ramos, G., Carvajal, M. E. (1999) Effect of glycine on hemoglobin glycation in diabetic patients. Proc. West Pharmacol. Soc. 42: 31-32
7. Cederberg, J., Simán, C. M., Eriksson, U. J. (2001) Combined treatment with vitamin E and vitamin C decreases oxidative stress and improves fetal outcome in experimental diabetic pregnancy. Pediatr. Res. 49: 755-762
8. Choi, K. T. (1994) Effect of hyperglycemia on glutamate, glycine and aspartate concentrations during peri-ischemic periods in the rabbit hippocampus. Korean J. Anesthesiol. 27: 128-135
9. Choi, K. T., Illievich, U. M., Zornow, M. H., Scheller, M. S., Strnat, M. A. (1994) Effect of hyperglycemia on peri-ischemic neuro-transmitter levels in the rabbit hippocampus. Brain Res. 642: 104-110
10. Cockroft, K. L. (1990) Dissection and culture of postimplantation embryos. In: Copp, A. J., Cockroft, D. L. (eds) Postimplantation mammalian embryos. A practical approach. IRL Press, New York, pp 15-40
11. Eriksson, U. J., Borg, L. A. (1993) Diabetes and embryonic malformations. Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos. Diabetes 42: 411-419
12. Gäreskog, M., Wentzel, P. (2007) N-Acetylcysteine and alpha-cyano-4-hydroxycinnamic acid alter protein kinase C (PKC)-delta and PKC-zeta and diminish dysmorphogenesis in rat embryos cultured with high glucose in vitro. J. Endocrinol. 92: 207-214
13. Hunter, E. S., Phillips, L. S., Goldstein, S., Sadler, T. W. (1991) Altered visceral yolk sac function produced by a low-molecular-weight somatomedin inhibitor. Teratology 43: 331-340
14. Jagetia, G. C., Ganapathi, N. G., Unnikrishnan, M. K. (1993) Copperglycinate protects mice exposed to various doses of gamma radiation. Strahlenther Onkol. 169: 323-328
15. Jankowski, M. A., Uriu-Hare, J. Y., Rucker, R. B., Roger, J. M., Keen, C. L. (1995) Maternal zinc deficiency, but not copper deficiency or diabetes, results in increased embryonic cell death in the rat. Implications for mechanism underlying abnormal development. Teratology 51: 85-93
16. Khandelwal, M., Reece, E. A., Wu, Y. K., Borenstein, M. (1998) Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. Teratology 57: 79-84
17. Klug, S. (1991) Whole embryo culture: interpretation of abnormal development in vitro. Reprod. Toxicol. 5: 237-244
18. Kubow, S., Yaylayan, V., Mandevlle, S. (1993) Protection by acetyl-salicylic acid against hyperglycemia-induced glycation and neural tube defects in cultured early somite mouse embryos. Diabetes Res. 22: 145-148
19. Labarca, C., Paigen, K. (1980) A simple, rapid and sensitive DNA assay procedure. Anal. Biochem. 102: 344-352
20. Landauer, W. (1976) Cholinomimetic teratogens, III. Interaction with amino acids known as neurotransmitters. Teratology 13: 41-46
21. Lee, A. T., Reis, D., Eriksson, U. J. (1999) Hyperglycemia-induced embryonic dysmorphogenesis correlates with genomic DNA mutation frequency in vitro and in vivo. Diabetes 48: 371-376
22. Li, Q., Bowmer, C. J., Yates, M. S. (1995) Amelioration of cisplatin nephrotoxicity with glycine: dose dependency in rats. J. Pharm. Phamacol. 47: 223-226
23. Mangino, M. J., Murphy, M. K., Grabau, G. G., Anderson, C. B. (1991) Protective effects of glycine during hypothermic renal ischemia-reperfusion injury. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol 30): F841-F848
24. Martínez, E., Garcia, A., Saenz, A., Garduño, L., Salazar, M., Chamorro, G. (2003) The effects of glycine therapy on the fetal outcome of diabetic mice. Pharm. Biol. 41: 449-453
25. McDearmid, J. R., Liao, M., Drapeau, P. (2006) Glycine receptors regulate interneuron differentiation during spinal network development. Proc. Natl Acad. Sci. USA 103: 9679-9684
26. Ogasawara, M., Nakamura, T., Koyama, I., Nemoto, M., Yoshida, T. (1994) Reactivity of taurine with aldehydes and its physiological role. Adv. Exp. Med. Biol. 359: 71-78
27. Paniagua-Castro, N., Escalona-Cardoso, G., Chamorro-Cevallos, G. (2007) Glycine reduces cadmium-induced teratogenicity in mice. Reprod. Toxicol. 23: 92-97
28. Pinter, E., Reece, E., Leranth, C. Z., Garcia-Segura, M., Hobbins, J. C., Mahoney, M. J., Naftolin, F. (1986) Arachidonic acid prevents hyperglycemia-associated yolk sac damage and embryopathy. Am. J. Obstet. Gynecol. 155: 1691-702
29. Pollak, A., Salzer, H. R., Lischka, A., Hayde, M. (1988) Non-enzymatic glycation of fetal tissue in diabetic pregnancy. Acta Paediatr. Scand. 77: 481-484
30. Ramakrishnan, S., Sulochana, K. N. (1993) Decrease in glycation of lens proteins by lysine and glycine by scavenging of glucose and possible mitigation of cataractogenesis. Exp. Eye. Res. 57: 623-628
31. Reece, E. A., Homko, C. J., Wu, Y. K. (1996) Multifactorial basis of the syndrome of diabetic embryopathy. Teratology 54: 171-182
32. Reece, E. A., Wu, Y. K., Zhao, Z., Dhanasekaran, D. (2006) Dietary vitamin and lipid therapy rescues aberrant signaling and apoptosis and prevents hyperglycemia-induced diabetic embryopathy in rats. Am. J. Obstet. Gynecol. 194: 580-585
33. Rossen, B., Miodovnick, M., Combs, A., Khoury, J., Siddiqi, T. A. (1994) Glycemic thresholds for spontaneous abortion and congenital malformations in insulin-dependent diabetes mellitus. Obstet. Gynecol. 84: 515-520
34. Singh, V., Ahmad, S., Rao, G. S. (1994) Prooxidant and antioxidant properties of iron-hydroquinone and iron-1,2,4-benzenotriol complex. Implications for benzene toxicity. Toxicology 89: 25-33
35. The Diabetes Control and Complications Trial Research Group (1996) Pregnancy outcomes in the diabetes control and complications trial. Am. J. Obstet. Gynecol. 174: 1343-1353
36. Weinberg, J. M., Venkatachalam, M. A., Garza-Quintero, R., Roeser, N. F., Davis, J. A. (1990) Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules. FASEB J. 4: 3347-3354
37. Weinberg, J. M., Varani, J., Johnson, K., Roeser, N. F., Dame, M. K., Davis, J. A., Venkatachalam, M. A. (1992) Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury. Am. J. Pathol. 140: 457-471
38. Wentzel, P., Thunberg, L., Eriksson, U. J. (1997) Teratogenic effect of diabetic serum is prevented by supplementation of superoxide dismutase and N-acetylcysteine in rat embryo culture. Diabetologia 40:7-14
39. Wheeler, M. D., Thurman, R. G. (1999) Production of superoxide and TNF-α from alveolar macrophages is blunted by glycine. Am. J. Physiol. Lung Cell Mol. Physiol. 277: L952-L959
40. Yin, M., Ikejima, K., Arteel, G. E., Seabra, V., Bradford, B. U., Kono, H., Rusyn, I., Thurman, R. G. (1998) Glycine accelerates recovery from alcohol-induced liver injury. J. Pharmacol. Exp. Ther. 286: 1014-1019