Chapter 18 Visualization of Desmosomes in the Electron Microscope

Methods in Cell Biology

Volumn 88, Issue , 2008, Pages 347-366

  Scothern, Anthea ^a   Garrod, David ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GOLD; METAL NANOPARTICLE;

ANIMAL; BIOLOGICAL MODEL; CRYOPRESERVATION; DESMOSOME; ELECTRON MICROSCOPY; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; REVIEW; ULTRASTRUCTURE;

ANIMALS; CRYOPRESERVATION; DESMOSOMES; GOLD; HUMANS; IMMUNOHISTOCHEMISTRY; METAL NANOPARTICLES; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL;

EID: 46249111914     PISSN: 0091679X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0091-679X(08)00418-4     Document Type: Review

References (42)

1. Al-Amoudi A., Norlen L.P., and Dubochet J. Cryo-electron microscopy of vitreous sections of native biological cells and tissues. J. Struct. Biol. 148 (2004) 131-135
2. Bardsley W.G., Ackerman R.A., Bukhari N.A., Deeming D.C., and Ferguson M.W. Mathematical models for growth in alligator (Alligator mississippiensis) embryos developing at different incubation temperatures. J. Anat. 187 Pt 1 (1995) 181-190
3. Bardsley W.G., Bukhari N.A.J., Ferguson M.W.J., Cachaza J.A., and Burguillo F.J. Evaluation of model discrimination, parameter-estimation and goodness-of-fit in nonlinear-regression problems by test statistics distributions. Comput. Chem. 19 (1995) 75-84
4. Breathnach A.S., and Wyllie M.A. The problem of the Langerhans cells. In: Montagna W., and Hu F. (Eds). Advances in Biology of Skin: The Pigmentary System (1967), Pergamon Press, Oxford
5. Burdett I.D. Aspects of the structure and assembly of desmosomes. Micron 29 (1998) 309-328
6. Chidgey M., and Dawson C. Desmosomes: A role in cancer?. Br. J. Cancer 96 (2007) 1783-1787
7. Dusek R.L., Godsel L.M., and Green K.J. Discriminating roles of desmosomal cadherins: Beyond desmosomal adhesion. J. Dermatol. Sci. 45 (2007) 7-21
8. Fujimoto K. Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J. Cell Sci. 108 Pt 11 (1995) 3443-3449
9. Garrod D.R., Berika M.Y., Bardsley W.F., Holmes D., and Tabernero L. Hyper-adhesion in desmosomes: Its regulation in wound healing and possible relationship to cadherin crystal structure. J. Cell Sci. 118 (2005) 5743-5754
10. Garrod D.R., Merritt A.J., and Nie Z. Desmosomal cadherins. Curr. Opin. Cell Biol. 14 (2002) 537-545
11. Garrod D.R., Merritt A.J., and Nie Z. Desmosomal adhesion: Structural basis, molecular mechanism and regulation (Review). Mol. Membr. Biol. 19 (2002) 81-94
12. Getsios S., Huen A.C., and Green K.J. Working out the strength and flexibility of desmosomes. Nat. Rev. Mol. Cell Biol. 5 (2004) 271-281
13. Griffiths G., McDowall A., Back R., and Dubochet J. On the preparation of cryosections for immunocytochemistry. J. Ultrastruct. Res. 89 (1984) 65-78
14. Hatzfeld M. The armadillo family of structural proteins. Int. Rev. Cytol. 186 (1999) 179-224
15. Hatzfeld M. Plakophilins: Multifunctional proteins or just regulators of desmosomal adhesion?. Biochim. Biophys. Acta 1773 (2007) 69-77
16. He W., Cowin P., and Stokes D.L. Untangling desmosomal knots with electron tomography. Science 302 (2003) 109-113
17. Kelly D.E. Fine structure of desmosomes., hemidesmosomes, and an adepidermal globular layer in developing new epidermis. J. Cell Biol. 28 (1966) 51-72
18. Kelly D.E., and Kuda A.M. Traversing filaments in desmosomal and hemidesmosomal attachments: Freeze-fracture approaches toward their characterization. Anat. Rec. 199 (1981) 1-14
19. Kelly D.E., and Shienvold F.L. The desmosome: Fine structural studies with freeze-fracture replication and tannic acid staining of sectioned epidermis. Cell Tissue Res. 172 (1976) 309-323
20. Kottke M.D., Delva E., and Kowalczyk A.P. The desmosome: Cell science lessons from human diseases. J. Cell Sci. 119 (2006) 797-806
21. Liou W., Geuze H.J., and Slot J.W. Improving structural integrity of cryosections for immunogold labeling. Histochem. Cell Biol. 106 (1996) 41-58
22. Miller K., Mattey D., Measures H., Hopkins C., and Garrod D. Localisation of the protein and glycoprotein components of bovine nasal epithelial desmosomes by immunoelectron microscopy. EMBO J. 6 (1987) 885-889
23. North A.J., Bardsley W.G., Hyam J., Bornslaeger E.A., Cordingley H.C., Trinnaman B., Hatzfeld M., Green K.J., Magee A.I., and Garrod D.R. Molecular map of the desmosomal plaque. J. Cell Sci. 112 Pt 23 (1999) 4325-4336
24. North A.J., Chidgey M.A., Clarke J.P., Bardsley W.G., and Garrod D.R. Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis. Proc. Natl. Acad. Sci. USA 93 (1996) 7701-7705
25. North A.J., Galazkiewicz B., Byers T.J., Glenney Jr. J.R., and Small J.V. Complementary distributions of vinculin and dystrophin define two distinct sarcolemma domains in smooth muscle. J. Cell Biol. 120 (1993) 1159-1167
26. North A.J., Gimona M., Cross R.A., and Small J.V. Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells. J. Cell Sci. 107 Pt 3 (1994) 437-444
27. North A.J., Gimona M., Lando Z., and Small J.V. Actin isoform compartments in chicken gizzard smooth muscle cells. J. Cell Sci. 107 Pt 3 (1994) 445-455
28. North A.J., and Small J.V. Immunofluorescent labelling of sections. In: Allen V.J.E. (Ed). Protein Localization by Fluorescence Microscopy (2000), Oxford University Press
29. Orwin D.F., Thomson R.W., and Flower N.E. Plasma membrane differentiations of keratinizing cells of the wool follicle. II. Desmosomes. J. Ultrastruct. Res. 45 (1973) 15-29
30. Parrish E.P., Garrod D.R., Mattey D.L., Hand L., Steart P.V., and Weller R.O. Mouse antisera specific for desmosomal adhesion molecules of suprabasal skin cells, meninges, and meningioma. Proc. Natl. Acad. Sci. USA 83 (1986) 2657-2661
31. Peters P.J., Borst J., Oorschot V., Fukuda M., Krahenbuhl O., Tschopp J., Slot J.W., and Geuze H.J. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J. Exp. Med. 173 (1991) 1099-1109
32. Peters P.J., Bos E., and Griekspoor A. Cryo-immunogold electron microscopy (Unit 4.7). Current Protocols in Cell Biology (2006), John Wiley & Sons, New York
33. Rayns D.G., Simpson F.O., and Ledingham J.M. Ultrastructure of desmosomes in mammalian intercalated disc; appearances after lanthanum treatment. J. Cell Biol. 42 (1969) 322-326
34. Shimizu A., Ishiko A., Ota T., Saito H., Oka H., Tsunoda K., Amagai M., and Nishikawa T. In vivo ultrastructural localization of the desmoglein 3 adhesive interface to the desmosome mid-line. J. Invest. Dermatol. 124 (2005) 984-989
35. Small J.V., Furst D.O., and De M.J. Localization of filamin in smooth muscle. J. Cell Biol. 102 (1986) 210-220
36. Staehelin L.A. Structure and function of intercellular junctions. Int. Rev. Cytol. 39 (1974) 191-283
37. Tokuyasu K.T. A technique for ultracryotomy of cell suspensions and tissues. J. Cell Biol. 57 (1973) 551-565
38. Tokuyasu K.T. Immunochemistry on ultrathin frozen sections. Histochem. J. 12 (1980) 381-403
39. Tokuyasu K.T. Application of cryoultramicrotomy to immunocytochemistry. J. Microsc. 143 (1986) 139-149
40. Tokuyasu K.T. Use of poly(vinylpyrrolidone) and poly(vinyl alcohol) for cryoultramicrotomy. Histochem. J. 21 (1989) 163-171
41. Tokuyasu K.T., and Singer S.J. Improved procedures for immunoferritin labeling of ultrathin frozen sections. J. Cell Biol. 71 (1976) 894-906
42. Yin T., and Green K.J. Regulation of desmosome assembly and adhesion. Semin. Cell Dev. Biol. 15 (2004) 665-677