Changes in the plasmodial surface anion channel reduce leupeptin uptake and can confer drug resistance in Plasmodium falciparum-infected erythrocytes

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 7, 2008, Pages 2346-2354

  Lisk, Godfrey ^a   Pain, Margaret ^a   Gluzman, Ilya Y ^b   Kambhampati, Shivkumar ^a   Furuya, Tetsuya ^a   Su, Xin Zhuan ^a   Fay, Michael P ^a   Goldberg, Daniel E ^b   Desai, Sanjay A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANION CHANNEL; CYSTEINE PROTEINASE; LEUPEPTIN; SERINE PROTEINASE;

ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG UPTAKE; ENZYME ACTIVITY; ERYTHROCYTE; ERYTHROCYTE FRAGILITY; HUMAN; HUMAN CELL; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ANTIMALARIALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE PERMEABILITY; CYSTEINE PROTEINASE INHIBITORS; DRUG RESISTANCE; ERYTHROCYTES; GENES, PROTOZOAN; HUMANS; ION CHANNELS; LEUPEPTINS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

EID: 46249107664     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00057-08     Document Type: Article

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