Caspase activation as an apoptotic evidence in the gerbil hippocampal CA1 pyramidal cells following transient forebrain ischemia

Neuroscience Letters

Volumn 300, Issue 2, 2001, Pages 103-106

  Niwa, Masayuki ^a   Hara, Akira ^a   Iwai, Tomohiko ^b   Wang, Shaotan ^a   Hotta, Koichi ^a   Mori, Hideki ^a   Uematsu, Toshihiko ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Gifu Municipal Hospital   (Japan)

Author keywords

Caspase; Delayed neuronal death; DNA fragmentation; Forebrain ischemia; Gerbil

Indexed keywords

CASPASE; CASPASE 3; DNA FRAGMENT; URIDINE TRIPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVATION; GERBIL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NEUROPATHOLOGY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; CASPASE 3; CASPASES; DNA FRAGMENTATION; GERBILLINAE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; ISCHEMIC ATTACK, TRANSIENT; KERATINS; MALE; NERVE DEGENERATION; PYRAMIDAL CELLS; TIME FACTORS;

EID: 0035831308     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01559-2     Document Type: Article

References (20)

1. Continuing postischemic neuronal death in CA1: Influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats
2. Major DNA fragmentation is a late event in apoptosis
3. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
4. Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia
5. Protective effect of apoptosis-inhibitory agent, N-tosyl-L-phenylalanyl chloromethyl ketone against ischemia-induced hippocampal neuronal damage
6. Neuronal apoptosis studied by a sequential TUNEL technique: A method for tract-tracing
7. Temporal profile of nuclear DNA fragmentation in situ in gerbil hippocampus following transient forebrain ischemia
8. Delayed neuronal death in the gerbil hippocampus following ischemia
9. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
10. Actin polymerization and depolymerization during apoptosis in HL-60 cells
11. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
12. Release of cytochrome c from mitochondria to cytosol in gerbil hippocampal CA1 neurons after transient forebrain ischemia
13. Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons
14. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
15. Relationship between magnitude of hypothermia during ischemia and preventive effect against post-ischemic DNA fragmentation in the gerbil hippocampus
16. Cytochrome C is released from mitochondria into the cytosol after cerebral anoxia or ischemia
17. Delayed hippocampal damage in humans following cardiorespiratory arrest
18. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischemia in the rat
19. Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation
20. In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system