Understanding allergy

Paediatrics and Child Health

Volumn 18, Issue 7, 2008, Pages 301-308

  Sohi, Dalbir K ^a,b   Warner, John O ^a,b  

^a IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^b London ^*  (United Kingdom)

Author keywords

allergy; early life origins; hygiene hypothesis; immunopathology; prevalence; prevention

Indexed keywords

CD14 ANTIGEN; CD4 ANTIGEN; FOOD ALLERGEN; GAMMA INTERFERON; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 23; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA;

ALLERGIC ASTHMA; ALLERGIC DISEASE; ALLERGIC RHINITIS; ALLERGY; ARTICLE; ATOPIC DERMATITIS; CHILD; CYTOKINE PRODUCTION; EPIDEMIC; FOOD ALLERGY; HUMAN; HYGIENE; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; INFANT NUTRITION; MATERNAL NUTRITION; PREVALENCE; QUALITY OF LIFE; REGULATORY T LYMPHOCYTE; SENSITIZATION; TH1 CELL; TH2 CELL; UNITED KINGDOM;

EID: 45849140565     PISSN: 17517222     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.paed.2008.04.006     Document Type: Article

References (34)

1. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet 351 (1998) 1225-1232
2. Grundy J., Matthews S., Bateman B., Dean T., and Arshad S.H. Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts. J Allergy Clin Immunol 110 (2002) 784-789
3. Gupta R., Sheikh A., Strachan D.P., and Anderson H.R. Time trends in allergic disorders in the UK. Thorax 62 (2007) 91-96
4. Allergy: the unmet need. A blueprint for better patient care. A report of The Royal College of Physicians Working Party on the provision of allergy services in the UK. June 2003.
5. Austin J.B., Kaur B., Anderson H.R., et al. Hay fever, eczema, and wheeze: a nationwide UK study (ISAAC, international study of asthma and allergies in childhood). Arch Dis Child 81 (1999) 225-230
6. Ninan T., Russell G., and Devenny A. Changes in the prevalence of respiratory symptoms and atopy in Aberdeen school children. Eur Respir J 16 suppl 31 (2000) 342s
7. Devenny A., Wassall H., Ninan T., Omran M., Khan S.D., and Russell G. Respiratory symptoms and atopy in children in Aberdeen: questionnaire studies of a defined school population repeated over 35 years. BMJ 329 (2004) 489-490
8. Asher M.I., Montefort S., Bjorksten B., et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 368 (2006) 733-743
9. Barnetson R.S., and Rogers M. Childhood atopic eczema. BMJ 324 (2002) 1376-1379
10. Almqvist C., Li Q., Britton W.J., et al. Early predictors for developing allergic disease and asthma: examining separate steps in the 'allergic march'. Clin Exp Allergy 37 (2007) 1296-1302
11. Spergel J.M., Mizoguchi E., Brewer J.P., Martin T.R., Bhan A.K., and Geha R.S. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest 101 (1998) 1614-1622
12. Callard R.E., and Harper J.I. The skin barrier, atopic dermatitis and allergy: a role for Langerhans cells?. Trends Immunol 28 (2007) 294-298
13. Rhodes H.L., Thomas P., Sporik R., Holgate S.T., and Cogswell J.J. A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. Am J Respir Crit Care Med 165 (2002) 176-180
14. Jones A.C., Miles E.A., Warner J.O., Colwell B.M., Bryant T.N., and Warner J.A. Fetal peripheral blood mononuclear cell proliferative responses to mitogenic and allergenic stimuli during gestation. Pediatr Allergy Immunol 7 (1996) 109-116
15. Jones C.A., Holloway J.A., and Warner J.O. Does atopic disease start in foetal life?. Allergy 55 (2000) 2-10
16. Van Duren-Schmidt K., Pichler J., Ebner C., et al. Prenatal contact with inhalant allergens. Pediatr Res 41 (1997) 128-131
17. Prescott S.L., Macaubas C., Smallacombe T., Holt B.J., Sly P.D., and Holt P.G. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 353 (1999) 196-200
18. Strachan D.P. Hay fever, hygiene, and household size. BMJ 299 (1989) 1259-1260
19. Gruber C., Illi S., Lau S., et al. Transient suppression of atopy in early childhood is associated with high vaccination coverage. Pediatrics 111 (2003) e282-e288
20. Custovic A., and Simpson A. Environmental allergen exposure, sensitisation and asthma: from whole populations to individuals at risk. Thorax 59 (2004) 825-827
21. Vance G.H., Grimshaw K.E., Briggs R., et al. Serum ovalbumin-specific immunoglobulin G responses during pregnancy reflect maternal intake of dietary egg and relate to the development of allergy in early infancy. Clin Exp Allergy 34 (2004) 1855-1861
22. Butland B.K., Strachan D.P., and Anderson H.R. Fresh fruit intake and asthma symptoms in young British adults: confounding or effect modification by smoking?. Eur Respir J 13 (1999) 744-750
23. Shaheen S.O., Newson R.B., Henderson A.J., Emmett P.M., Sherriff A., and Cooke M. Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema. Eur Respir J 24 (2004) 292-297
24. Dunstan J.A., Mori T.A., Barden A., et al. Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial. J Allergy Clin Immunol 112 (2003) 1178-1184
25. Wjst M. The triple T allergy hypothesis. Clin Dev Immunol 11 (2004) 175
26. Laubereau B., Brockow I., Zirngibl A., et al. Effect of breast-feeding on the development of atopic dermatitis during the first 3 years of life-results from the GINI-birth cohort study. J Pediatr 144 (2004) 602-607
27. Kramer M.S., Matush L., Vanilovich I., et al. Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial. BMJ 335 (2007) 815
28. Rothenbacher D., Weyermann M., Beermann C., and Brenner H. Breastfeeding, soluble CD14 concentration in breast milk and risk of atopic dermatitis and asthma in early childhood: birth cohort study. Clin Exp Allergy 35 (2005) 1014-1021
29. Lack G., Fox D., Northstone K., and Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med 348 (2003) 977-985
30. Guandalini S. The influence of gluten: weaning recommendations for healthy children and children at risk for celiac disease. Nestle Nutr Workshop Ser Pediatr Program 60 (2007) 139-151
31. Department of Health. Leaflet product number 278960. http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_4117080
32. Kalliomaki M., Salminen S., Arvilommi H., Kero P., Koskinen P., and Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 357 (2001) 1076-1079
33. Abrahamsson T.R., Jakobsson T., Bottcher M.F., et al. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol 119 (2007) 1174-1180
34. Osborn D., and Sinn J. Prebiotics in infants for prevention of allergic disease and food hypersensitivity. Cochrane Database Syst Rev 4 (2007) CD006474