Environmental allergen exposure, sensitisation and asthma: From whole populations to individuals at risk

Thorax

Volumn 59, Issue 10, 2004, Pages 825-827

  Custovic, A ^a   Simpson, A ^a  

^a WYTHENSHAWE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN;

ALLERGY; ASTHMA; COCKROACH; COHORT ANALYSIS; DOSE RESPONSE; EDITORIAL; ENVIRONMENTAL EXPOSURE; HEALTH PROGRAM; HIGH RISK POPULATION; HUMAN; LONGITUDINAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; SENSITIZATION; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOLOGY;

ALLERGENS; ASTHMA; ENVIRONMENTAL EXPOSURE; HUMANS; HYPERSENSITIVITY; IMMUNIZATION; LONGITUDINAL STUDIES;

EID: 6344221598     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2004.027334     Document Type: Editorial

References (39)

1. NACMAAS): risk factors for asthma and allergic disorders in adults. Clin Exp Allergy 2001;31:391-9.
2. Pearce N, Pekkanen J, Beasley R. How much asthma is really attributable to atopy? Thorax 1999;54:268-72.
3. Pearce N, Douwes J, Beasley R. Is allergen exposure the major primary cause of asthma? Thorax 2000;55:424-31.
4. Kuehr J, Frischer T, Meinert R, et al. Mite allergen exposure is a risk for the incidence of specific sensitisation. J Allergy Clin Immunol 1994;94:44-52.
5. Sporik R, Squillace SP, Ingram JM, et al. Mite, cat and cockroach exposure, allergen sensitisation and asthma in children: a case-control study of three schools. Thorax 1999;54:675-80.
6. Lau S, Falkenhorst G, Weber A, et al. High mite-allergen exposure increases the risk of sensitization in atopic children and young adults. J Allergy Clin Immunol 1989;84:718-25.
7. Huss K, Adkinson NF Jr, Eggleston PA, et al. House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol 2001;107:48-54.
8. Peat JK, Tovey E, Toelle BG, et al. House dust mite allergens. A major risk factor for childhood asthma in Australia. Am J Respir Crit Care Med 1996;153:141-6.
9. Eggleston PA, Rosenstreich D, Lynn H, et al. Relationship of indoor allergen exposure to skin test sensitivity in inner-city children with asthma. J Allergy Clin Immunol 1998;102:563-70.
10. Phipatanakul W, Eggleston PA, Wright EC, et al. Mouse allergen. II. The relationship of mouse allergen exposure to mouse sensitization and asthma morbidity in inner-city children with asthma. J Allergy Clin Immunol 2000;106:1075-80.
11. Custovic A, Simpson BM, Simpson A, et al. Current mite, cat and dog allergen exposure, pet ownership and sensitization to inhalant allergens in adults. J Allergy Clin Immunol 2003;111:402-7.
12. Custovic A, Hallam CL, Simpson BM, et al. Decreased prevalence of sensitization to cats with high exposure to cat allergen. J Allergy Clin Immunol 2001;108:537-9.
13. Platts-Mills T, Vaughan J, Squillace S, et al. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 2001;357:752-6.
14. Nickel R, Lau S, Niggemann B, et al. Messages from the German Multicentre Allergy Study. Pediatr Allergy Immunol 2002;13(Suppl 15):7-10.
15. Wickman M, Kull I, Pershagen G, et al. The BAMSE Project: presentation of a prospective longitudinal birth cohort study. Pediatr Allergy Immunol 2002;13(Suppl 15):11-13.
16. Brunekreef B, Smit J, Jongste J, et al. The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results. Pediatr Allergy Immunol 2002;13(Suppl 15):55-60.
17. Custovic A, Simpson BM, Murray CS, et al. The National Asthma Campaign Manchester Asthma and Allergy Study. Pediatr Allergy Immunol 2002;13(Suppl 15):32-7.
18. Cullinan P, MacNeill SJ, Harris JM, et al. Early allergen exposure, skin prick responses and atopic wheeze at age five in English children: a cohort study. Thorax 2004;59:855-61.
19. Wahn U, Lau S, Bergmann R, et al. Indoor allergen exposure is a risk factor for sensitisation during the first three years of life. J Allergy Clin Immunol 1997;99:763-9.
20. Lau S, Illi S, Sommerfeld C, et al. Early exposure to house dust mite and cat allergens and development of childhood asthma: a cohort study. Lancet 2000;356:1392-7.
21. Arshad SH, Tariq SM, Matthews S, et al. Sensitisation to common allergens and its association with allergic disorders at age 4 years: a whole population birth cohort study. Pediatrics 2001;108:e33.
22. Sporik R, Holgate ST, Platts-Mills TA, et al. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med 1990;323:502-7.
23. Burr ML, Limb ES, Maguire MJ, et al. Infant feeding, wheezing, and allergy: a prospective study. Arch Dis Child 1993;68:724-8.
24. Arshad SH, Matthews S, Gant C, et al. Effect of allergen avoidance on development of allergic disorders in infancy. Lancet 1992;339:1493-7.
25. Hide DW, Matthews S, Matthews L, et al. Effect of allergen avoidance in infancy on allergic manifestations at age 2 years. J Allergy Clin Immunol 1994;93:842-6.
26. Hide DW, Matthews S, Tariq S, et al. Allergen avoidance in infancy and allergy at 4 years of age. Allergy 1996;51:89-93.
27. Arshad SH, Bateman B, Matthews SM. Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomized controlled study. Thorax 2003;58:489-93.
28. Chan-Yeung M, Ferguson A, Dimich-Ward H, et al. Effectiveness and compliance to intervention measures in reducing house dust and cat allergen levels. Ann Allergy Asthma Immunol 2002;88:52-8.
29. Chan-Yeung M, Manfreda J, Dimich-Ward H, et al. A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants. Arch Pediatr Adolesc Med 2000;154:657-63.
30. Becker A, Watson W, Ferguson A, et al. The Canadian Asthma Primary Prevention Study: outcomes at 2 years of age. J Allergy Clin Immunol 2004;113:650-6.
31. Halmerbauer G, Gartner C, Schierl M, et al. Study on the Prevention of Allergy in Children in Europe (SPACE): allergic sensitization at 1 year of age in a controlled trial of allergen avoidance from birth. Pediatr Allergy Immunol 2003;14:10-17.
32. Mihrshahi S, Peat JK, Marks GB, et al. Eighteen-month outcomes of house dust mite avoidance and dietary fatty acid modification in the Childhood Asthma Prevention Study (CAPS). J Allergy Clin Immunol 2003;111:162-8.
33. Peat JK, Mihrshahi S, Kemp AS, et al. Three year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study (CAPS). J Allergy Clin Immunol 2004 (in press).
34. van Strien R, Koopman L, Kerkhof M, et al. Mattress encasings and mite allergen levels in the prevention and incidence of asthma and mite allergy study. Clin Exp Allergy 2003;33:490-5.
35. Koopman LP, van Strien R, Kerkhof M, et al. Placebo-controlled trial of house dust mite-impermeable mattress covers: effect on symptoms in early childhood. Am J Respir Crit Care Med 2002;166:307-13.
36. Custovic A, Simpson BM, Simpson A, et al. Manchester Asthma and Allergy Study: low allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol 2000;105:252-8.
37. Simpson A, Simpson B, Custovic A, et al. Stringent environmental control in pregnancy and early life: the long term effects on mite, cat and dog allergen. Clin Exp Allergy 2003;33:1183-9.
38. Custovic A, Simpson BM, Simpson A, et al. Environmental control in pregnancy and early life: effect on respiratory symptoms and atopy during the first year of life. Lancet 2001;31:1194-204.
39. Woodcock A, Lowe LA, Murray CS, et al. Early life environmental control: effect on symptoms, sensitization and lung function at age 3 years. Am J Respir Crit Care Med 2004;170:433-9.