Leptin induces the expression of functional tissue factor in human neutrophils and peripheral blood mononuclear cells through JAK2-dependent mechanisms and TNFα involvement

Thrombosis Research

Volumn 122, Issue 3, 2008, Pages 366-375

  Rafail, S ^a   Ritis, K ^a   Schaefer, K ^b   Kourtzelis, I ^a   Speletas, M ^c   Doumas, M ^a   Giaglis, S ^d   Kambas, K ^a   Konstantinides, S ^b   Kartalis, G ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF THESSALY   (Greece)

^d BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

Leptin; Neutrophils; Thrombosis; Tissue factor; TNF

Indexed keywords

JANUS KINASE 2; LEPTIN; MESSENGER RNA; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NEUTROPHIL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTHROMBIN TIME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOOD COAGULATION; HUMANS; INFLAMMATION; JANUS KINASE 2; LEPTIN; LEUKOCYTES, MONONUCLEAR; NEUTROPHILS; OBESITY; PLATELET AGGREGATION; PROTHROMBIN TIME; RNA, MESSENGER; THROMBOPLASTIN; THROMBOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 45849125000     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2007.12.018     Document Type: Article

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