Inhibition of rostral medullary raphé neurons prevents cold-induced activity in sympathetic nerves to rat tail and rabbit ear arteries

Neuroscience Letters

Volumn 357, Issue 1, 2004, Pages 58-62

  Ootsuka, Youichirou ^a,b   Blessing, William W ^a   McAllen, Robin M ^b  

^a FLINDERS UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Body temperature; Cutaneous sympathetic nerves; Presympathetic neurons; Rabbit ear pinna; Rat tail; Thermoregulation

Indexed keywords

GLYCINE; MUSCIMOL; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; COLD; CONTROLLED STUDY; COOLING; DRUG EFFECT; EAR ARTERY; EXTERNAL EAR; MALE; MICROINJECTION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAPHE NUCLEUS; RAT; SKIN BLOOD FLOW; SKIN BLOOD VESSEL; SYMPATHETIC NERVE; TAIL ARTERY; THERMOREGULATION; VASOMOTOR REFLEX;

EID: 0442323510     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2003.11.067     Document Type: Article

References (21)

1. Blessing W.W., Nalivaiko E. Raphe magnus/pallidus neurons regulate tail but not mesenteric arterial blood flow in rats. Neuroscience. 105:2001;923-929.
2. Blessing W.W., Nalivaiko E. Regional blood flow and nociceptive stimuli in rabbits: patterning by medullary raphe, not ventrolateral medulla. J. Physiol. 524:2000;279-292.
3. Blessing W.W., Seaman B., Pedersen N.P., Ootsuka Y. Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats. J. Neurosci. 23:2003;6385-6391.
4. Bonaz B., Tache Y. Induction of Fos immunoreactivity in the rat brain after cold-restraint induced gastric lesions and fecal excretion. Brain Res. 652:1994;56-64.
5. Grant R.T., Bland E.F., Camp P.D. Observations on the vessels and nerves of the rabbit's ear with special reference to the reaction to cold. Heart. 16:1932;69-101.
6. Hayes K.H., Weaver L.C. Selective control of sympathetic pathways to the kidney, spleen and intestine by the ventrolateral medulla in rats. J. Physiol. (Lond.). 428:1990;371-385.
7. Kanosue K., Hosono T., Zhang Y.H., Chen X.M. Neuronal networks controlling thermoregulatory effectors. Prog. Brain Res. 115:1998;49-62.
8. Martin-Cora F.J., Fornal C.A., Metzler C.W., Jacobs B.L. Single-unit responses of serotonergic medullary and pontine raphe neurons to environmental cooling in freely moving cats. Neuroscience. 98:2000;301-309.
9. McAllen R.M. Mediation of the fastigial pressor response and a somatosympathetic reflex by ventral medullary neurones in the cat. J. Physiol. (Lond.). 368:1985;423-433.
10. Morrison S.F. Raphe pallidus neurons mediate prostaglandin E2-evoked increases in brown adipose tissue thermogensis. Neuroscience. 121:2003;17-24.
11. Morrison S.F. RVLM and raphe differentially regulate sympathetic outflows to splanchnic and brown adipose tissue. Am. J. Physiol. 276:1999;R962-R973.
12. Morrison S.F., Sved A.F., Passerin A.M. GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue. Am. J. Physiol. 276:1999;R290-R297.
13. Nakamura K., Matsumura K., Kaneko T., Kobayashi S., Katoh H., Negishi M. The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area. J. Neurosci. 22:2002;4600-4610.
14. Owens N.C., Ootsuka Y., Kanosue K., McAllen R.M. Thermoregulatory control of sympathetic fibres supplying the rat's tail. J. Physiol. 543:2002;849-858.
15. Rand R.P., Burton A.C., Ing T. The tail of the rat, in temperature regulation and acclimatization. Can. J. Physiol. Pharmacol. 43:1965;257-267.
16. Rathner J.A., Owens N.C., McAllen R.M. Cold-activated raphe-spinal neurons in rats. J. Physiol. 535:2001;841-854.
17. Riedel W., Iriki M., Simon E. Regional differentiation of sympathetic activity during peripheral heating and cooling in anesthetized rabbits. Pflugers Arch. 332:1972;239-247.
18. Sawasaki N., Iwase S., Mano T. Effect of skin sympathetic response to local or systemic cold exposure on thermoregulatory functions in humans. Auton. Neurosci. 87:2001;274-281.
19. Smith J.E., Jansen A.S., Gilbey M.P., Loewy A.D. CNS cell groups projecting to sympathetic outflow of tail artery: neural circuits involved in heat loss in the rat. Brain Res. 786:1998;153-164.
20. Tanaka M., Nagashima K., McAllen R.M., Kanosue K. Role of the medullary raphe in thermoregulatory vasomotor control in rats. J. Physiol. 540:2002;657-664.
21. Walther O.E., Riedel W., Iriki M., Simon E. Differentiation of sympathetic activity at the spinal level in response to central cold stimulation. Pflugers Arch. 329:1971;220-230.