Asbestos-induced MKP-3 expression augments TNF-α gene expression in human monocytes

American Journal of Respiratory Cell and Molecular Biology

Volumn 39, Issue 1, 2008, Pages 113-123

  Tephly, Linda A ^a   Carter, A Brent ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Asbestos; MAP kinase; Monocytes; Phosphatase; TNF

Indexed keywords

ASBESTOS; CROCIDOLITE; DUAL SPECIFICITY PHOSPHATASE 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASBESTOSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; MONOCYTE;

ADOLESCENT; ADULT; ASBESTOS; ASBESTOSIS; DUAL SPECIFICITY PHOSPHATASE 6; FORCED EXPIRATORY VOLUME; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MACROPHAGES, ALVEOLAR; MIDDLE AGED; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REFERENCE VALUES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 45849093976     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2007-0356OC     Document Type: Article

References (64)

1. Hance AJ, Douches S, Winchester RJ, Ferrans VJ, Crystal RG. Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J Immunol 1985;134:284-292.
2. Peters-Golden M, McNish RW, Brieland JK, Fantone JC. Diminished protein kinase C-activated arachidonate metabolism accompanies rat macrophage differentiation in the lung. J Immunol 1990;144:4320-4326.
3. Schwartz DA, Galvin JR, Frees KL, Dayton CS, Burmeister LF, Merchant JA, Hunninghake GW. Clinical relevance of cellular mediators of inflammation in workers exposed to asbestos. Am Rev Respir Dis 1993;148:68-74.
4. Zhang Y, Lee TC, Guillemin B, Yu MC, Rom WN. Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure. J Immunol 1993;150:4188-4196.
5. Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-746.
6. Lee JC, Young PR. Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J Leukoc Biol 1996;59:152-157.
7. Carter AB, Knudtson KL, Monick MM, Hunninghake GW. The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression: the role of TATA-binding protein (TBP). J Biol Chem 1999;274:30858-30863.
8. Carter AB, Monick MM, Hunninghake GW. Both Erk and p38 kinases are necessary for cytokine gene transcription. Am J Respir Cell Mol Biol 1999;20:751-758.
9. Monick MM, Carter AB, Flaherty DM, Peterson MW, Hunninghake GW. Protein kinase Cζ plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages. J Immunol 2000;165:4632-4639.
10. Monick MM, Carter AB, Gudmundsson G, Mallampalli R, Powers LS, Hunninghake GW. A phosphatidylcholine-specific phospholipase C regulates activation of p42/44 mitogen-activated protein kinases in lipopolysaccharide- stimulated human alveolar macrophages. J Immunol 1999;162:3005-3012.
11. Hoffmeyer A, Grosse-Wilde A, Flory E, Neufeld B, Kunz M, Rapp UR, Ludwig S. Different mitogen-activated protein kinase signaling pathways cooperate to regulate tumor necrosis factor alpha gene expression in T lymphocytes. J Biol Chem 1999;274:4319-4327.
12. Rawadi G, Ramez V, Lemercier B, Roman-Roman S. Activation of mitogen-activated protein kinase pathways by Mycoplasma fermentans membrane lipoproteins in murine macrophages: involvement in cytokine synthesis. J Immunol 1998;160:1330-1339.
13. 2 signaling in human alveolar macrophages. Am J Respir Cell Mol Biol 2004;31:43-53.
14. 2. Am J Physiol 1997;273:L1029-L1035.
15. Buder-Hoffmann S, Palmer C, Vacek P, Taatjes D, Mossman B. Different accumulation of activated extracellular signal-regulated kinases (ERK 1/2) and role in cell-cycle alterations by epidermal growth factor, hydrogen peroxide, or asbestos in pulmonary epithelial cells. Am J Respir Cell Mol Biol 2001;24:405-413.
16. Ramos-Nino ME, Timblin CR, Mossman BT. Mesothelial cell transformation requires increased AP-1 binding activity and ERK-dependent Fra-1 expression. Cancer Res 2002;62:6065-6069.
17. Swain WA, O'Byrne KJ, Faux SP. Activation of p38 MAP kinase by asbestos in rat mesothelial cells is mediated by oxidative stress. Am J Physiol Lung Cell Mol Physiol 2004;286:L859-L865.
18. Yuan Z, Taatjes DJ, Mossman BT, Heintz NH. The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Cancer Res 2004;64:6530-6536.
19. Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 2000;14:6-16.
20. Keyse SM. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Curr Opin Cell Biol 2000;12:186-192.
21. Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999;13:2905-2927.
22. Camps M, Nichols A, Gillieron C, Antonsson B, Muda M, Chabert C, Boschert U, Arkinstall S. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science 1998;280:1262-1265.
23. Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, Nichols A. MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2α. J Biol Chem 2004;279:44731-44739.
24. Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J 1996;15:3621-3632.
25. Fjeld CC, Rice AE, Kim Y, Gee KR, Denu JM. Mechanistic basis for catalytic activation of mitogen-activated protein kinase phosphatase 3 by extracellular signal-regulated kinase. J Biol Chem 2000;275:6749-6757.
26. Nichols A, Camps M, Gillieron C, Chabert C, Brunet A, Wilsbacher J, Cobb M, Pouyssegur J, Shaw JP, Arkinstall S. Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3. J Biol Chem 2000;275:24613-24621.
27. Zhou B, Wu L, Shen K, Zhang J, Lawrence DS, Zhang ZY. Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2. J Biol Chem 2001;276:6506-6515.
28. Zhou B, Zhang ZY. Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2. J Biol Chem1999;274:35526-35534.
29. Krombach F, Gerlach JT, Padovan C, Burges A, Behr J, Beinert T, Vogelmeier C. Characterization and quantification of alveolar monocyte-like cells in human chronic inflammatory lung disease. Eur Respir J 1996;9:984-991.
30. Striz I, Wang YM, Svarcova I, Trnka L, Sorg C, Costabel U. The phenotype of alveolar macrophages and its correlation with immune cells in bronchoalveolar lavage. Eur Respir J 1993;6:1287-1294.
31. Bergeron A, Bonay M, Kambouchner M, Lecossier D, Riquet M, Soler P, Hance A, Tazi A. Cytokine patterns in tuberculous and sarcoid granulomas: correlations with histopathologic features of the granulomatous response. J Immunol 1997;159:3034-3043.
32. Bernaudin JF, Yamauchi K, Wewers MD, Tocci MJ, Ferrans VJ, Crystal RG. Demonstration by in situ hybridization of dissimilar IL-1β gene expression in human alveolar macrophages and blood monocytes in response to lipopolysaccharide. J Immunol 1988;140:3822-3829.
33. Bitterman PB, Wewers MD, Rennard SI, Adelberg S, Crystal RG. Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. J Clin Invest 1986;77:700-708.
34. Strieter RM, Remick DG, Lynch JPD, Genord M, Raiford C, Spengler R, Kunkel SL. Differential regulation of tumor necrosis factor-alpha in human alveolar macrophages and peripheral blood monocytes: a cellular and molecular analysis. Am J Respir Cell Mol Biol 1989;1:57-63.
35. Goldfeld AE, Doyle C, Maniatis T. Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. Proc Natl Acad Sci USA 1990;87:9769-9773.
36. Wartmann M, Hofer P, Turowski P, Saltiel AR, Hynes NE. Negative modulation of membrane localization of the Raf-1 protein kinase by hyperphosphorylation. J Biol Chem 1997;272:3915-3923.
37. Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005;120:649-661.
38. Tephly LA, Carter AB. Differential expression and oxidation of MKP-1 modulates TNF-α gene expression. Am J Respir Cell Mol Biol 2007;37:366-374.
39. Rom WN, Bitterman PB, Rennard SI, Cantin A, Crystal RG. Characterization of the lower respiratory tract inflammation of nonsmoking individuals with interstitial lung disease associated with chronic inhalation of inorganic dusts. Am Rev Respir Dis 1987;136:1429-1434.
40. Spurzem JR, Saltini C, Rom W, Winchester RJ, Crystal RG. Mechanisms of macrophage accumulation in the lungs of asbestos-exposed subjects. Am Rev Respir Dis 1987;136:276-280.
41. Kiemle-Kallee J, Kreipe H, Radzun HJ, Parwaresch MR, Auerswald U, Magnussen H, Barth J. Alveolar macrophages in idiopathic pulmonary fibrosis display a more monocyte-like immunophenotype and an increased release of free oxygen radicals. Eur Respir J 1991;4:400-406.
42. Iwamoto GK, Monick MM, Burmeister LF, Hunninghake GW. Interleukin 1 release by human alveolar macrophages and blood monocytes. Am J Physiol 1989;256:C1012-C1015.
43. Standiford TJ, Kunkel SL, Rolfe MW, Evanoff HL, Allen RM, Strieter RM. Regulation of human alveolar macrophage- and blood monocyte-derived interleukin-8 by prostaglandin E2 and dexamethasone. Am J Respir Cell Mol Biol 1992;6:75-81.
44. Hancock A, Armstrong L, Gama R, Millar A. Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. Am J Respir Cell Mol Biol 1998;18:60-65.
45. Carter AB, Hunninghake GW. A constitutive active MEK→ERK pathway negatively regulates NF-κB-dependent gene expression by modulating TATA-binding protein phosphorylation. J Biol Chem 2000;275:27858-27864.
46. Colucci-D'Amato GL, D'Alessio A, Califano D, Cali G, Rizzo C, Nitsch L, Santelli G, de Franciscis V. Abrogation of nerve growth factor-induced terminal differentiation by ret oncogene involves perturbation of nuclear translocation of ERK. J Biol Chem 2000;275:19306-19314.
47. Karlsson M, Mathers J, Dickinson RJ, Mandl M, Keyse SM. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal. J Biol Chem 2004;279:41882-41891.
48. Cheung PY, Zhang Y, Long J, Lin S, Zhang M, Jiang Y, Wu Z. p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs. J Biol Chem 2004;279:45308-45311.
49. Kang YJ, Seit-Nebi A, Davis RJ, Han J. Multiple activation mechanisms of p38a mitogen-activated protein kinase. J Biol Chem 2006;281:26225-26234.
50. Perchonock CE, Fernando MC, Quinn WJ III, Nguyen CT, Sun J, Shapiro MJ, Shapiro VS. Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX. Mol Cell Biol 2006;26:6005-6015.
51. Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 1996;16:1247-1255.
52. Monick MM, Carter AB, Gudmundsson G, Geist LJ, Hunninghake GW. Changes in PKC isoforms in human alveolar macrophages compared with blood monocytes. Am J Physiol 1998;275:L389-L397.
53. Zhang C, Baumgartner RA, Yamada K, Beaven MA. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. J Biol Chem 1997;272:13397-13402.
54. Singh RP, Dhawan P, Golden C, Kapoor GS, Mehta KD. One-way cross-talk between p38(MAPK) and p42/44(MAPK): inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade. J Biol Chem 1999;274:19593-19600.
55. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270:1326-1331.
56. Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP, Liew FY. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J Immunol 1999;163:6403-6412.
57. 2+-dependent signal pathways in Rat-1 cells. J Biol Chem 1997;272:13309-13319.
58. 2-terminal kinase and mitogen-activated protein kinase signaling pathways. J Exp Med 1996;183:2017-2023.
59. Minden A, Lin A, Smeal T, Derijard B, Cobb M, Davis R, Karin M. c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases. Mol Cell Biol 1994;14:6683-6688.
60. Nakajima T, Kinoshita S, Sasagawa T, Sasaki K, Naruto M, Kishimoto T, Akira S. Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6. Proc Natl Acad Sci USA 1993;90:2207-2211.
61. Ahn NG, Seger R, Bratlien RL, Diltz CD, Tonks NK, Krebs EG. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J Biol Chem 1991;266:4220-4227.
62. Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW. Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase). EMBO J 1991;10:885-892.
63. Robbins DJ, Cobb MH. Extracellular signal-regulated kinases 2 autophosphorylates on a subset of peptides phosphorylated in intact cells in response to insulin and nerve growth factor: analysis by peptide mapping. Mol Biol Cell 1992;3:299-308.
64. Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, Cobb MH. Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. J Biol Chem 1993;268:5097-5106.