메뉴 건너뛰기




Volumn 33, Issue 2, 2008, Pages 127-140

Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats

Author keywords

Apoptosis; Ascorbic acid; Cell proliferation; Hepatocarcinogenesis; Kojic acid; Reactive oxygen species (ROS)

Indexed keywords

ASCORBIC ACID; CELL NUCLEUS ANTIGEN; DIETHYLNITROSAMINE; DRINKING WATER; GLUTATHIONE TRANSFERASE; KOJIC ACID; MALONALDEHYDE; MESSENGER RNA; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 45749118682     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.33.127     Document Type: Article
Times cited : (7)

References (51)
  • 2
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in check-point control and cancer
    • Bartek, J. and Lukas, J. (2003) : Chk1 and Chk2 kinases in check-point control and cancer. Cancer Cell, 3, 421-429.
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 3
    • 0347990545 scopus 로고    scopus 로고
    • Greater tolerance of renal medullary cells for a slow increase in osmolality is associated with enhanced expression of HSP70 and other osmoprotective genes
    • Cai, Q., Ferraris, J.D. and Burg, M.B. (2004) : Greater tolerance of renal medullary cells for a slow increase in osmolality is associated with enhanced expression of HSP70 and other osmoprotective genes. Am. J. Physiol. Renal Physiol., 286, 58-67.
    • (2004) Am. J. Physiol. Renal Physiol , vol.286 , pp. 58-67
    • Cai, Q.1    Ferraris, J.D.2    Burg, M.B.3
  • 4
    • 0018757414 scopus 로고
    • Ascorbic acid and cancer: A review
    • Cameron, E., Pauling, L. and Leibovitz, B. (1979) : Ascorbic acid and cancer: a review. Cancer Res., 39, 663-681.
    • (1979) Cancer Res , vol.39 , pp. 663-681
    • Cameron, E.1    Pauling, L.2    Leibovitz, B.3
  • 6
    • 16244373054 scopus 로고    scopus 로고
    • Modulation of light-induced skin tumors by N-acetyl-cysteine and/or ascorbic acid in hairless mice
    • D'Agostini, F., Balansky, R.M., Camoirano, A. and De Flora, S. (2005a) : Modulation of light-induced skin tumors by N-acetyl-cysteine and/or ascorbic acid in hairless mice. Carcinogenesis, 26, 657-664.
    • (2005) Carcinogenesis , vol.26 , pp. 657-664
    • D'Agostini, F.1    Balansky, R.M.2    Camoirano, A.3    De Flora, S.4
  • 8
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alterations of metabolism
    • Dang, C.V. and Semenza, G.L. (1999) : Oncogenic alterations of metabolism. Trends Biochem. Sci., 24, 68-72.
    • (1999) Trends Biochem. Sci , vol.24 , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 9
    • 0036216386 scopus 로고    scopus 로고
    • Feroze, M.F., Berquin, I.M., Dey, J. and Chen, Y.Q. (2002) : Peptidylprolyl isomerase A (PPIA) as a preferred internal control over GAPDH and beta-actin in quantitative RNA analyses. Biotechniques, 32, 776-778, 780, 782.
    • Feroze, M.F., Berquin, I.M., Dey, J. and Chen, Y.Q. (2002) : Peptidylprolyl isomerase A (PPIA) as a preferred internal control over GAPDH and beta-actin in quantitative RNA analyses. Biotechniques, 32, 776-778, 780, 782.
  • 10
    • 0041703021 scopus 로고    scopus 로고
    • 1-induced suppression of glutathione antioxidant defenses in hepatocytes: Caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms
    • 1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms. FASEB J., 17, 1535-1537.
    • (2003) FASEB J , vol.17 , pp. 1535-1537
    • Franklin, C.C.1    Rosenfeld-Franklin, M.E.2    White, C.3    Kavanagh, T.J.4    Fausto, N.5
  • 11
    • 0001218860 scopus 로고
    • Ascorbate is an outstanding antioxidant in human blood plasma
    • Frei, B., England, L. and Ames, B.N. (1989) : Ascorbate is an outstanding antioxidant in human blood plasma. Proc. Natl. Acad. Sci. USA, 86, 6377-6381.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6377-6381
    • Frei, B.1    England, L.2    Ames, B.N.3
  • 13
    • 0032818870 scopus 로고    scopus 로고
    • Changes in thyroid function during development of thyroid hyperplasia induced by kojic acid in F344 rats
    • Fujimoto, N., Onodera, H., Mitsumori, K., Tamura, T., Maruyama, S. and Ito, A. (1999) : Changes in thyroid function during development of thyroid hyperplasia induced by kojic acid in F344 rats. Carcinogenesis, 20, 1567-1571.
    • (1999) Carcinogenesis , vol.20 , pp. 1567-1571
    • Fujimoto, N.1    Onodera, H.2    Mitsumori, K.3    Tamura, T.4    Maruyama, S.5    Ito, A.6
  • 14
    • 0347318117 scopus 로고    scopus 로고
    • Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes
    • Herrera, B., Murillo, M.M., Alvarez-Barrientos, A., Beltràn, J., Fernandez, M. and Fabregat, I. (2004) : Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes. Free Radic. Biol. Med., 36, 16-26.
    • (2004) Free Radic. Biol. Med , vol.36 , pp. 16-26
    • Herrera, B.1    Murillo, M.M.2    Alvarez-Barrientos, A.3    Beltràn, J.4    Fernandez, M.5    Fabregat, I.6
  • 15
    • 34249800077 scopus 로고    scopus 로고
    • Kojic acid - absence of tumor-initiating activity in rat liver, and of carcinogenic and photo-genotoxic potential in mouse skin
    • Higa, Y., Kawabe, M., Nabae, K., Toda, Y., Kitamoto, S., Hara, T., Tanaka, N., Kariya, K. and Takahashi, M. (2007) : Kojic acid - absence of tumor-initiating activity in rat liver, and of carcinogenic and photo-genotoxic potential in mouse skin. J. Toxicol. Sci., 32, 143-159.
    • (2007) J. Toxicol. Sci , vol.32 , pp. 143-159
    • Higa, Y.1    Kawabe, M.2    Nabae, K.3    Toda, Y.4    Kitamoto, S.5    Hara, T.6    Tanaka, N.7    Kariya, K.8    Takahashi, M.9
  • 17
    • 0035955438 scopus 로고    scopus 로고
    • Induction of caspase-11 by inflammatory stimuli in rat astrocytes: Lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway
    • Hur, J., Kim, S.Y., Kim, H., Cha, S., Lee, M.S. and Suk, K. (2001) : Induction of caspase-11 by inflammatory stimuli in rat astrocytes: lipopolysaccharide induction through p38 mitogen-activated protein kinase pathway. FEBS Lett., 507, 157-162.
    • (2001) FEBS Lett , vol.507 , pp. 157-162
    • Hur, J.1    Kim, S.Y.2    Kim, H.3    Cha, S.4    Lee, M.S.5    Suk, K.6
  • 18
    • 0034037455 scopus 로고    scopus 로고
    • Early detection of carcinogenic substances and modifiers in rats
    • Ito, N., Imaida, K., Asamoto, M. and Shirai, T. (2000) : Early detection of carcinogenic substances and modifiers in rats. Mutat. Res., 462, 209-217.
    • (2000) Mutat. Res , vol.462 , pp. 209-217
    • Ito, N.1    Imaida, K.2    Asamoto, M.3    Shirai, T.4
  • 20
    • 0027076383 scopus 로고    scopus 로고
    • Katoh, S., Toyama, J., Kodama, I., Kamiya, K., Akita, T. and Abe, T. (1992) : Protective action of iron-chelating agents (catechol, mimosine, deferoxamine, and kojic acid) against ischemia-reperfusion injury of isolated neonatal rabbit hearts. Eur. Surg. Res., 24, 349-355.
    • Katoh, S., Toyama, J., Kodama, I., Kamiya, K., Akita, T. and Abe, T. (1992) : Protective action of iron-chelating agents (catechol, mimosine, deferoxamine, and kojic acid) against ischemia-reperfusion injury of isolated neonatal rabbit hearts. Eur. Surg. Res., 24, 349-355.
  • 21
    • 0025614933 scopus 로고
    • A study on the regulation of translocation of glucose transporters during hepatocarcinogenesis induced by 3′-Me DAB
    • Kim, Y.S., Paik, E.M., Lee, M.S., Kim, K.S., Chai, K.J. and Ahn, Y.H. (1990) : A study on the regulation of translocation of glucose transporters during hepatocarcinogenesis induced by 3′-Me DAB. Yonsei Med. J., 31, 315-324.
    • (1990) Yonsei Med. J , vol.31 , pp. 315-324
    • Kim, Y.S.1    Paik, E.M.2    Lee, M.S.3    Kim, K.S.4    Chai, K.J.5    Ahn, Y.H.6
  • 22
    • 35848958360 scopus 로고    scopus 로고
    • Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid
    • Kono, T., Moto, M., Muguruma, M., Takahashi, M., Jin, M., Kenmochi, Y., Yokouchi, Y. and Mitsumori, K. (2007) : Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid. J. Vet. Sci., 69, 899-908.
    • (2007) J. Vet. Sci , vol.69 , pp. 899-908
    • Kono, T.1    Moto, M.2    Muguruma, M.3    Takahashi, M.4    Jin, M.5    Kenmochi, Y.6    Yokouchi, Y.7    Mitsumori, K.8
  • 23
  • 26
    • 0001185061 scopus 로고
    • In vitro effectiveness of several whitening cosmetic components in human melanocytes
    • Maeda, K. and Fukuda, M. (1991) : In vitro effectiveness of several whitening cosmetic components in human melanocytes. J. Soc. Cosmet. Chem., 42, 361-368.
    • (1991) J. Soc. Cosmet. Chem , vol.42 , pp. 361-368
    • Maeda, K.1    Fukuda, M.2
  • 27
    • 0032897025 scopus 로고    scopus 로고
    • Promoting effects of kojic acid due to serum TSH elevation resulting from reduced serum thyroid hormone levels on development of thyroid proliferative lesions in rats initiated with N-bis(2-hydr oxypropyl)nitrosamine
    • Mitsumori, K., Onodera, H., Takahashi, M., Funakoshi, T., Tamura, T., Yasuhara, K., Takegawa, K. and Takahashi, M. (1999) : Promoting effects of kojic acid due to serum TSH elevation resulting from reduced serum thyroid hormone levels on development of thyroid proliferative lesions in rats initiated with N-bis(2-hydr oxypropyl)nitrosamine. Carcinogenesis, 20, 173-176.
    • (1999) Carcinogenesis , vol.20 , pp. 173-176
    • Mitsumori, K.1    Onodera, H.2    Takahashi, M.3    Funakoshi, T.4    Tamura, T.5    Yasuhara, K.6    Takegawa, K.7    Takahashi, M.8
  • 28
    • 33645887223 scopus 로고    scopus 로고
    • Absence of liver tumor-initiating activity of kojic acid in mice
    • Moto, M., Mori, T., Okamura, M., Kashida, Y. and Mitsumori, K. (2006a). Absence of liver tumor-initiating activity of kojic acid in mice. Arch. Toxicol., 80, 299-304.
    • (2006) Arch. Toxicol , vol.80 , pp. 299-304
    • Moto, M.1    Mori, T.2    Okamura, M.3    Kashida, Y.4    Mitsumori, K.5
  • 29
    • 33748703427 scopus 로고    scopus 로고
    • Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice
    • Moto, M., Umemura, T., Okamura, M., Muguruma, M., Ito, T., Jin, M., Kashida, Y. and Mitsumori, K. (2006b) : Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice. Arch. Toxicol., 80, 694-702.
    • (2006) Arch. Toxicol , vol.80 , pp. 694-702
    • Moto, M.1    Umemura, T.2    Okamura, M.3    Muguruma, M.4    Ito, T.5    Jin, M.6    Kashida, Y.7    Mitsumori, K.8
  • 31
    • 0037365968 scopus 로고    scopus 로고
    • Specificity of a third kind: Reactive oxygen and nitrogen intermediates in cell signaling
    • Nathan, C. (2003) : Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. J. Clin. Invest., 111, 769-778.
    • (2003) J. Clin. Invest , vol.111 , pp. 769-778
    • Nathan, C.1
  • 32
    • 0242494349 scopus 로고    scopus 로고
    • An assessment of the genotoxicity and human health risk of topical use of kojic acid (5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one)
    • Nohynek, G.J., Kirkland, D., Marzin, D., Toutain, H., Leclerc-Ribaud, C. and Jinnai, H. (2004) : An assessment of the genotoxicity and human health risk of topical use of kojic acid (5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one). Food Chem. Toxicol., 42, 93-105.
    • (2004) Food Chem. Toxicol , vol.42 , pp. 93-105
    • Nohynek, G.J.1    Kirkland, D.2    Marzin, D.3    Toutain, H.4    Leclerc-Ribaud, C.5    Jinnai, H.6
  • 33
    • 33645966193 scopus 로고    scopus 로고
    • Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N′-nitro-N- nitrosoguanidine: Possible contribution of nitric oxide-associated oxidative DNA damage
    • Okazaki, K., Ishii, Y., Kitamura, Y., Maruyama, S., Umemura, T., Miyauchi, M., Yamagishi, M., Imazawa, T., Nishikawa, A., Yoshimura, Y., Nakazawa, H. and Hirose, M. (2006) : Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N′-nitro-N- nitrosoguanidine: Possible contribution of nitric oxide-associated oxidative DNA damage. Cancer Sci., 97, 175-182.
    • (2006) Cancer Sci , vol.97 , pp. 175-182
    • Okazaki, K.1    Ishii, Y.2    Kitamura, Y.3    Maruyama, S.4    Umemura, T.5    Miyauchi, M.6    Yamagishi, M.7    Imazawa, T.8    Nishikawa, A.9    Yoshimura, Y.10    Nakazawa, H.11    Hirose, M.12
  • 34
    • 18144440321 scopus 로고
    • Production of aflatoxins and kojic acid by species of Aspergillus and Penicillium
    • Parrish, F.W., Wiley, B.J., Simmons, E.G. and Long Jr., L. (1966) : Production of aflatoxins and kojic acid by species of Aspergillus and Penicillium. Appl. Microbiol., 14, 139.
    • (1966) Appl. Microbiol , vol.14 , pp. 139
    • Parrish, F.W.1    Wiley, B.J.2    Simmons, E.G.3    Long Jr., L.4
  • 35
    • 33845762723 scopus 로고    scopus 로고
    • Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase
    • Perez-Cruz, I., Cárcamo, J.M. and Golde, D.W. (2007) : Caspase-8 dependent TRAIL-induced apoptosis in cancer cell lines is inhibited by vitamin C and catalase. Apoptosis, 12, 225-234.
    • (2007) Apoptosis , vol.12 , pp. 225-234
    • Perez-Cruz, I.1    Cárcamo, J.M.2    Golde, D.W.3
  • 39
    • 0021045327 scopus 로고
    • On the cytotoxicity of vitamin C and metal ions. A site-specific Fenton mechanism
    • Samuni, A., Aronovitch, J., Godinger, D., Chevion, M. and Czapski, G. (1983) : On the cytotoxicity of vitamin C and metal ions. A site-specific Fenton mechanism. Eur. J. Biochem., 137, 119-124.
    • (1983) Eur. J. Biochem , vol.137 , pp. 119-124
    • Samuni, A.1    Aronovitch, J.2    Godinger, D.3    Chevion, M.4    Czapski, G.5
  • 40
    • 0029991162 scopus 로고    scopus 로고
    • DNA-repair methyltransferase as a molecular device for preventing mutation and cancer
    • Sekiguchi, M., Nakabeppu, Y., Sakumi, K. and Tuzuki, T. (1996) : DNA-repair methyltransferase as a molecular device for preventing mutation and cancer. J. Cancer Res. Clin. Oncol., 122, 199-206.
    • (1996) J. Cancer Res. Clin. Oncol , vol.122 , pp. 199-206
    • Sekiguchi, M.1    Nakabeppu, Y.2    Sakumi, K.3    Tuzuki, T.4
  • 41
    • 0030756560 scopus 로고    scopus 로고
    • A medium-term rat liver bioassay as a rapid in vivo test for carcinogenic potential, a historical review of model development and summary of results from 291 tests
    • Shirai, T. (1997) : A medium-term rat liver bioassay as a rapid in vivo test for carcinogenic potential, a historical review of model development and summary of results from 291 tests. Toxicol. Pathol., 25, 453-460.
    • (1997) Toxicol. Pathol , vol.25 , pp. 453-460
    • Shirai, T.1
  • 42
  • 43
    • 4444254695 scopus 로고    scopus 로고
    • Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl) nitrosamine or N-diethylnitrosamine
    • Takizawa, T., Imai, T., Onose, J., Ueda, M., Tamura, T., Mitsumori, K., Izumi, K. and Hirose, M. (2004) : Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl) nitrosamine or N-diethylnitrosamine. Toxicol. Sci., 81, 43-49.
    • (2004) Toxicol. Sci , vol.81 , pp. 43-49
    • Takizawa, T.1    Imai, T.2    Onose, J.3    Ueda, M.4    Tamura, T.5    Mitsumori, K.6    Izumi, K.7    Hirose, M.8
  • 44
    • 0038172505 scopus 로고    scopus 로고
    • Hepatocellular tumor induction in heterozygous p53-deficient CBA mice by a 26-week dietary administration of kojic acid
    • Takizawa, T., Mitsumori, K., Tamura, T., Nasu, M., Ueda, M., Imai, T. and Hirose, M. (2003) : Hepatocellular tumor induction in heterozygous p53-deficient CBA mice by a 26-week dietary administration of kojic acid. Toxicol. Sci., 73, 287-293.
    • (2003) Toxicol. Sci , vol.73 , pp. 287-293
    • Takizawa, T.1    Mitsumori, K.2    Tamura, T.3    Nasu, M.4    Ueda, M.5    Imai, T.6    Hirose, M.7
  • 47
    • 27744483511 scopus 로고    scopus 로고
    • Induction of hepatocellular proliferative lesions in CBA mice by a 26-week dietary administration of kojic acid
    • Watanabe, T., Mori, T., Okamura, M., Kashida, Y. and Mitsumori, K (2005) : Induction of hepatocellular proliferative lesions in CBA mice by a 26-week dietary administration of kojic acid. J. Toxicol. Pathol., 18, 159-165.
    • (2005) J. Toxicol. Pathol , vol.18 , pp. 159-165
    • Watanabe, T.1    Mori, T.2    Okamura, M.3    Kashida, Y.4    Mitsumori, K.5
  • 49
    • 0037710752 scopus 로고    scopus 로고
    • Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo
    • Weishaupt, J.H., Diem, R., Kermer, P., Krajewski, S., Reed, J.C. and Bahr, M. (2003) : Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo. Neurobiol. Dis., 13, 124-135.
    • (2003) Neurobiol. Dis , vol.13 , pp. 124-135
    • Weishaupt, J.H.1    Diem, R.2    Kermer, P.3    Krajewski, S.4    Reed, J.C.5    Bahr, M.6
  • 50
    • 24144502074 scopus 로고    scopus 로고
    • Role of reactive oxygen species in angiotensin II-mediated renal growth, differentiation, and apoptosis
    • Wolf, G. (2005) : Role of reactive oxygen species in angiotensin II-mediated renal growth, differentiation, and apoptosis. Antioxid. Redox Signal., 7, 1337-1345.
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 1337-1345
    • Wolf, G.1
  • 51
    • 0242668686 scopus 로고    scopus 로고
    • Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling
    • Wood, Z.A., Poole, L.B. and Karplus, P.A. (2003) : Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science, 300, 650-653.
    • (2003) Science , vol.300 , pp. 650-653
    • Wood, Z.A.1    Poole, L.B.2    Karplus, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.