Enhancement of hepatocarcinogenesis by Kojik acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl) nitrosamine or N-diethylnitrosamine

Toxicological Sciences

Volumn 81, Issue 1, 2004, Pages 43-49

  Takizawa, Tamotsu ^a,b   Imai, Toshio ^a   Onose, Jun Ichi ^a   Ueda, Makoto ^a   Tamura, Toru ^a   Mitsumori, Kunitoshi ^a,c   Izumi, Keisuke ^b   Hirose, Masao ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIS(2 HYDROXYPROPYL)NITROSAMINE; CYCLINE; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; KOJIC ACID; 2 HYDROXYPROPYL N PROPYLNITROSAMINE; 2-HYDROXYPROPYL-N-PROPYLNITROSAMINE; ANTIOXIDANT; CARCINOGEN; GLUTATHIONE PEROXIDASE; NITROSAMINE; PYRONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CELL DIVISION; CELL VACUOLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CULTURE MEDIUM; HISTOPATHOLOGY; LIVER CANCER; LIVER CARCINOGENESIS; LIVER GRANULOMA; LIVER NECROSIS; LIVER WEIGHT; MALE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; ANIMAL; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; FISCHER 344 RAT; LIVER; LIVER TUMOR; METABOLISM; ORGAN SIZE; PATHOLOGY;

ANIMALIA; CRUSTACEA;

ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CARCINOGENS; DIETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; NITROSAMINES; ORGAN SIZE; PYRONES; RATS; RATS, INBRED F344;

EID: 4444254695     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh195     Document Type: Article

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