Functional mimicry of carboxypeptidase A by a combination of transition state stabilization and a defined orientation of catalytic moieties in molecularly imprinted polymers

Journal of the American Chemical Society

Volumn 130, Issue 25, 2008, Pages 8044-8054

  Liu, Jun Qiu ^b   Wulff, Günter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Jilin University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FOOD ADDITIVES; MOLECULAR ORIENTATION; NATURAL POLYMERS; POLYMERS; ZINC;

(1 1 1) ORIENTATION; CARBOXYPEPTIDASE A (CPA); MOLECULAR IMPRINTING; MOLECULARLY IMPRINTED POLYMERS (MIPS); NATURAL ENZYMES; SYNTHETIC POLYMERS; TRANSITION STATE (TS); TRANSITION STATE STABILIZATION;

FUNCTIONAL POLYMERS;

AMIDINE; CARBONIC ACID; CARBOXYPEPTIDASE A; COPPER ION; MONOMER; POLYMER; ZINC ION;

ARTICLE; CATALYST; COMPETITIVE INHIBITION; COMPLEX FORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; MOLECULAR INTERACTION; MOLECULAR MIMICRY; MOLECULAR MODEL; MOLECULAR STABILITY; POTENTIOMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

BIOMIMETICS; CARBOXYPEPTIDASES A; CATALYSIS; COPPER; MODELS, BIOLOGICAL; MOLECULAR IMPRINTING; MOLECULAR STRUCTURE; POLYMERS;

EID: 45749109415     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8012648     Document Type: Article

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