Functional mimicry of the active site of carboxypeptidase A by a molecular imprinting strategy: Cooperativity of an amidinium and a copper ion in a transition-state imprinted cavity giving rise to high catalytic activity

Journal of the American Chemical Society

Volumn 126, Issue 24, 2004, Pages 7452-7453

  Liu, Jun Qiu ^b   Wulff, Günter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; CARBOXYPEPTIDASE A; COPPER ION;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SUBSTRATE; MICHAELIS CONSTANT; MOLECULAR IMPRINTING; PH; PHASE TRANSITION; REACTION ANALYSIS; STRUCTURE ANALYSIS;

AMIDES; BINDING SITES; CARBOXYPEPTIDASES A; CATALYSIS; COPPER; KINETICS; MODELS, CHEMICAL; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; OXIDATION-REDUCTION;

EID: 2942682672     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja048372l     Document Type: Article

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