Molecular basis of cytotoxicity of Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in EBV latency III B cells: LMP1 induces type II ligand-independent autoactivation of CD95/fas with caspase 8-mediated apoptosis

Journal of Virology

Volumn 82, Issue 13, 2008, Pages 6721-6733

  Le Clorennec, Christophe ^a,g   Ouk, Tan Sothéa ^a   Youlyouz Marfak, Ibtissam ^a   Panteix, Stéphanie ^a   Martin, Catherine Claude ^a   Rastelli, Julia ^b,h   Adriaenssens, Eric ^c   Zimber Strobl, Ursula ^b   Coll, Jean ^d   Feuillard, Jean ^a,e   Jayat Vignoles, Chantal ^a,f  

^a UNIVERSITY OF LIMOGES   (France)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSERM   (France)

^d INSTITUT DE BIOLOGIE DE LILLE   (France)

^e DUPUYTREN UNIVERSITY HOSPITAL   (France)

^f CNRS   (France)

^g QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^h WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; DOXYCYCLINE; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LATENT MEMBRANE PROTEIN 1; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; ONCOPROTEIN; PROTEIN BID; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RECEPTOR;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DISEASE MARKER; ENZYME ACTIVATION; EPISOME; EPSTEIN BARR VIRUS; GENE OVEREXPRESSION; IMMUNOPRECIPITATION; LIPID RAFT; LYMPHOBLASTOID CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; WILD TYPE;

ANTIGENS, CD95; APOPTOSIS; B-LYMPHOCYTES; BLOTTING, WESTERN; CASPASE 8; CELL LINE, TUMOR; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; LUCIFERASES; MICROSCOPY, FLUORESCENCE; MITOCHONDRIAL MEMBRANES; NF-KAPPA B; RNA INTERFERENCE; VIRAL MATRIX PROTEINS;

HUMAN HERPESVIRUS 4;

EID: 45749103697     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02250-07     Document Type: Article

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