Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors

Journal of the American Chemical Society

Volumn 130, Issue 25, 2008, Pages 7822-7823

  McGlinchey, Ryan P ^a   Nett, Markus ^a   Eustáquio, Alessandra S ^a   Asolkar, Ratnakar N ^a   Fenical, William ^a   Moore, Bradley S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPROTEALIDE; NATURAL PRODUCT; PROTEASOME; PROTEASOME INHIBITOR; SALINOSPORAMIDE A; SALINOSPORAMIDE J; SALINOSPORAMIDE X1; SALINOSPORAMIDE X2;

ACTINOBACTERIA; ARTICLE; BACTERIAL GENE; BIOINFORMATICS; DRUG STRUCTURE; DRUG SYNTHESIS; GENE CLUSTER; GENETIC ENGINEERING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; REACTION ANALYSIS; SAL GENE; SALINISPORA TROPICA; STRUCTURE ANALYSIS;

LACTAMS; LACTONES; MICROMONOSPORACEAE; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ENGINEERING; PYRROLES;

EID: 45749102516     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8029398     Document Type: Article

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