CRM1-mediated nuclear export is required for 26 S proteasome-dependent degradation of the TRIP-Br2 proto-oncoprotein

Journal of Biological Chemistry

Volumn 283, Issue 17, 2008, Pages 11661-11676

  Cheong, Jit Kong ^a,b   Gunaratnam, Lakshman ^a   Hsu, Stephen I Hong ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINO ACIDS; CELL PROLIFERATION; COBALT; DEGRADATION; FLOW INTERACTIONS; MACHINERY; PORT TERMINALS; PROTEINS;

26S PROTEASOME; CELL CYCLES; EXPRESSION LEVELS; FAMILY MEMBERS; IMMUNOPRECIPITATION; IN CELLS; IN SILICO; INTERACTION DOMAINS; LEPTOMYCIN; LEUCINE RESIDUES; NUCLEAR EXPORT SIGNALS; NUCLEAR EXPORTS; ONCOPROTEIN; OVEREXPRESSION; PROTEASOME; TRANSACTIVATION DOMAINS; TUMORIGENESIS; UBIQUITIN;

NUCLEAR FUEL REPROCESSING;

EXPORTIN 1; LEPTOMYCIN B; LEUCINE; PROTEASOME; TRANSCRIPTIONAL REGULATOR INTERACTING WITH THE PHD BROMODOMAIN 2; UBIQUITIN; UNCLASSIFIED DRUG; ATP DEPENDENT 26S PROTEASE; CELL RECEPTOR; EXPORTIN 1 PROTEIN; KARYOPHERIN; SERTAD2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G1 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; MUTATION; NONHUMAN; NUCLEAR EXPORT SIGNAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN STABILITY; UBIQUITINATION; ACTIVE TRANSPORT; ANIMAL; BIOLOGICAL MODEL; CELL CYCLE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENE EXPRESSION REGULATION; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KARYOPHERINS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; UBIQUITIN;

EID: 45549110051     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708365200     Document Type: Article

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