Rapid and efficient radiosynthesis of [123I]I-PK11195, a single photon emission computed tomography tracer for peripheral benzodiazepine receptors

Nuclear Medicine and Biology

Volumn 35, Issue 5, 2008, Pages 537-542

  Pimlott, Sally L ^a   Stevenson, Louise ^b   Wyper, David J ^c   Sutherland, Andrew ^b  

^a WESTERN INFIRMARY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c SOUTHERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Benzodiazepine; Microglial; Neuroinflammation; PK11195; Radiosynthesis; Single photon emission computed tomography

Indexed keywords

BENZODIAZEPINE RECEPTOR; BROMINE; IODINE 123; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE I 123; PERACETIC ACID; TOSYLCHLORAMIDE SODIUM; TRACER;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ISOTOPE LABELING; MICROGLIA; RADIOCHEMISTRY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

CHLORAMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; INDICATORS AND REAGENTS; ISOQUINOLINES; ISOTOPE LABELING; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; SPECTROPHOTOMETRY, ULTRAVIOLET; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOSYL COMPOUNDS;

EID: 45549102860     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.02.013     Document Type: Article

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