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Volumn 109, Issue 3-5, 2008, Pages 307-313

Treatments for spinal cord injury: Is there hope in neurosteroids?

Author keywords

Bladder control; DHEA; Drug development; Methylprednisolone; Motor recovery; Neurosteroid; Sonic hedgehog; Spinal cord injury

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOPYRIDINE; NEUROSTEROID; PRASTERONE; PROGESTERONE; SONIC HEDGEHOG PROTEIN;

EID: 45449121003     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2008.03.022     Document Type: Article
Times cited : (17)

References (67)
  • 1
    • 0031817692 scopus 로고    scopus 로고
    • Spinal cord injury in the rat
    • Taoka Y., and Okajima K. Spinal cord injury in the rat. Prog. Neurobiol. 56 3 (1998) 341-358
    • (1998) Prog. Neurobiol. , vol.56 , Issue.3 , pp. 341-358
    • Taoka, Y.1    Okajima, K.2
  • 2
    • 33646577436 scopus 로고    scopus 로고
    • Degenerative and spontaneous regenerative processes after spinal cord injury
    • Hagg T., and Oudega M. Degenerative and spontaneous regenerative processes after spinal cord injury. J. Neurotrauma 23 3-4 (2006) 264-280
    • (2006) J. Neurotrauma , vol.23 , Issue.3-4 , pp. 264-280
    • Hagg, T.1    Oudega, M.2
  • 3
    • 0034125684 scopus 로고    scopus 로고
    • Clinical measurement, statistical analysis, and risk-benefit: controversies from trials of spinal injury
    • Bracken M.B., et al. Clinical measurement, statistical analysis, and risk-benefit: controversies from trials of spinal injury. J. Trauma 48 March (3) (2000) 558-561
    • (2000) J. Trauma , vol.48 , Issue.March 3 , pp. 558-561
    • Bracken, M.B.1
  • 4
    • 0032425112 scopus 로고    scopus 로고
    • Steroids and spinal cord injury: revisiting the nascis 2 and nascis 3 trials
    • Nesathurai S. Steroids and spinal cord injury: revisiting the nascis 2 and nascis 3 trials. J. Trauma 45 6 (1998) 1088-1093
    • (1998) J. Trauma , vol.45 , Issue.6 , pp. 1088-1093
    • Nesathurai, S.1
  • 5
    • 0036131321 scopus 로고    scopus 로고
    • Complications associated with the prophylactic use of methylprednisolone during surgical stabilization after spinal cord injury
    • Molano Mdel R., et al. Complications associated with the prophylactic use of methylprednisolone during surgical stabilization after spinal cord injury. J. Neurosurg. 96 Suppl. 3 (2002) 267-272
    • (2002) J. Neurosurg. , vol.96 , Issue.SUPPL. 3 , pp. 267-272
    • Molano Mdel, R.1
  • 6
    • 0033645496 scopus 로고    scopus 로고
    • High-dose methylprednisolone may do more harm for spinal cord injury
    • Qian T., et al. High-dose methylprednisolone may do more harm for spinal cord injury. Med. Hypotheses 55 5 (2000) 452-453
    • (2000) Med. Hypotheses , vol.55 , Issue.5 , pp. 452-453
    • Qian, T.1
  • 7
    • 0342647473 scopus 로고    scopus 로고
    • Methylprednisolone for acute spinal cord injury: an inappropriate standard of care
    • Hurlbert R.J. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J. Neurosurg. 93 Suppl. 1 (2000) 1-7
    • (2000) J. Neurosurg. , vol.93 , Issue.SUPPL. 1 , pp. 1-7
    • Hurlbert, R.J.1
  • 8
    • 33646790870 scopus 로고    scopus 로고
    • Strategies of medical intervention in the management of acute spinal cord injury
    • (discussion S36)
    • Hurlbert R.J. Strategies of medical intervention in the management of acute spinal cord injury. Spine 31 Suppl. 11 (2006) S16-S21 (discussion S36)
    • (2006) Spine , vol.31 , Issue.SUPPL. 11
    • Hurlbert, R.J.1
  • 9
    • 0034024692 scopus 로고    scopus 로고
    • High dose methylprednisolone in the management of acute spinal cord injury-a systematic review from a clinical perspective
    • Short D.J., et al. High dose methylprednisolone in the management of acute spinal cord injury-a systematic review from a clinical perspective. Spinal Cord 38 5 (2000) 273-286
    • (2000) Spinal Cord , vol.38 , Issue.5 , pp. 273-286
    • Short, D.J.1
  • 10
    • 0034812468 scopus 로고    scopus 로고
    • Acute spinal cord injury, part ii: contemporary pharmacotherapy
    • Dumont R.J., et al. Acute spinal cord injury, part ii: contemporary pharmacotherapy. Clin. Neuropharmacol. 24 5 (2001) 265-279
    • (2001) Clin. Neuropharmacol. , vol.24 , Issue.5 , pp. 265-279
    • Dumont, R.J.1
  • 11
    • 17444392322 scopus 로고    scopus 로고
    • Neuroprotection and acute spinal cord injury: a reappraisal
    • Hall E.D., and Springer J.E. Neuroprotection and acute spinal cord injury: a reappraisal. NeuroRx 1 1 (2004) 80-100
    • (2004) NeuroRx , vol.1 , Issue.1 , pp. 80-100
    • Hall, E.D.1    Springer, J.E.2
  • 12
    • 0029831520 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse
    • Li M., et al. Myelin-associated glycoprotein inhibits neurite/axon growth and causes growth cone collapse. J. Neurosci. Res. 46 4 (1996) 404-414
    • (1996) J. Neurosci. Res. , vol.46 , Issue.4 , pp. 404-414
    • Li, M.1
  • 13
    • 0031426869 scopus 로고    scopus 로고
    • Activated macrophages and the blood-brain barrier: Inflammation after cns injury leads to increases in putative inhibitory molecules
    • Fitch M.T., and Silver J. Activated macrophages and the blood-brain barrier: Inflammation after cns injury leads to increases in putative inhibitory molecules. Exp. Neurol. 148 2 (1997) 587-603
    • (1997) Exp. Neurol. , vol.148 , Issue.2 , pp. 587-603
    • Fitch, M.T.1    Silver, J.2
  • 14
    • 0034750201 scopus 로고    scopus 로고
    • Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors
    • Fouad K., et al. Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors. Brain Res. Brain Res. Rev. 36 2-3 (2001) 204-212
    • (2001) Brain Res. Brain Res. Rev. , vol.36 , Issue.2-3 , pp. 204-212
    • Fouad, K.1
  • 15
    • 0036550340 scopus 로고    scopus 로고
    • Ng2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors
    • Jones L.L., et al. Ng2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J. Neurosci. 22 7 (2002) 2792-2803
    • (2002) J. Neurosci. , vol.22 , Issue.7 , pp. 2792-2803
    • Jones, L.L.1
  • 16
    • 33746220096 scopus 로고    scopus 로고
    • The nogo receptor complex: confining molecules to molecular mechanisms
    • Schwab J.M., et al. The nogo receptor complex: confining molecules to molecular mechanisms. Trends Mol. Med. 12 7 (2006) 293-297
    • (2006) Trends Mol. Med. , vol.12 , Issue.7 , pp. 293-297
    • Schwab, J.M.1
  • 17
    • 33646926966 scopus 로고    scopus 로고
    • Antibodies against the ng2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord
    • Tan A.M., et al. Antibodies against the ng2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord. J. Neurosci. 26 18 (2006) 4729-4739
    • (2006) J. Neurosci. , vol.26 , Issue.18 , pp. 4729-4739
    • Tan, A.M.1
  • 18
    • 33747891298 scopus 로고    scopus 로고
    • Roles of eph receptors and ephrins in the normal and damaged adult cns
    • Goldshmit Y., et al. Roles of eph receptors and ephrins in the normal and damaged adult cns. Brain Res. Brain Res. Rev. 52 2 (2006) 327-345
    • (2006) Brain Res. Brain Res. Rev. , vol.52 , Issue.2 , pp. 327-345
    • Goldshmit, Y.1
  • 19
    • 0036286136 scopus 로고    scopus 로고
    • Inhibition of axon growth by oligodendrocyte precursor cells
    • Chen Z.J., et al. Inhibition of axon growth by oligodendrocyte precursor cells. Mol. Cell. Neurosci. 20 1 (2002) 125-139
    • (2002) Mol. Cell. Neurosci. , vol.20 , Issue.1 , pp. 125-139
    • Chen, Z.J.1
  • 20
    • 13444261145 scopus 로고    scopus 로고
    • Strategies for developing Nogo antagonists
    • Prinjha R.K., et al. Strategies for developing Nogo antagonists. Drug discovery today vol1 (2004) 21-27
    • (2004) Drug discovery today vol1 , pp. 21-27
    • Prinjha, R.K.1
  • 21
    • 0033711895 scopus 로고    scopus 로고
    • A critical role for a rho-associated kinase, p160rock, in determining axon outgrowth in mammalian cns neurons
    • Bito H., et al. A critical role for a rho-associated kinase, p160rock, in determining axon outgrowth in mammalian cns neurons. Neuron 26 2 (2000) 431-441
    • (2000) Neuron , vol.26 , Issue.2 , pp. 431-441
    • Bito, H.1
  • 22
    • 0036895744 scopus 로고    scopus 로고
    • Nogo-a and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of rhoa and rac1
    • Niederost B., et al. Nogo-a and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of rhoa and rac1. J. Neurosci. 22 23 (2002) 10368-10376
    • (2002) J. Neurosci. , vol.22 , Issue.23 , pp. 10368-10376
    • Niederost, B.1
  • 23
    • 33644814987 scopus 로고    scopus 로고
    • Neuronal responses to myelin are mediated by rho kinase
    • Alabed Y.Z., et al. Neuronal responses to myelin are mediated by rho kinase. J. Neurochem. 96 6 (2006) 1616-1625
    • (2006) J. Neurochem. , vol.96 , Issue.6 , pp. 1616-1625
    • Alabed, Y.Z.1
  • 24
    • 33344463671 scopus 로고    scopus 로고
    • Experimental strategies to promote spinal cord regeneration-an integrative perspective
    • Schwab J.M., et al. Experimental strategies to promote spinal cord regeneration-an integrative perspective. Prog. Neurobiol. 78 2 (2006) 91-116
    • (2006) Prog. Neurobiol. , vol.78 , Issue.2 , pp. 91-116
    • Schwab, J.M.1
  • 25
    • 0032759046 scopus 로고    scopus 로고
    • Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord
    • Mcdonald J.W., et al. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat. Med. 5 12 (1999) 1410-1412
    • (1999) Nat. Med. , vol.5 , Issue.12 , pp. 1410-1412
    • Mcdonald, J.W.1
  • 26
    • 0036935096 scopus 로고    scopus 로고
    • Grafts of bdnf-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy
    • Liu Y., et al. Grafts of bdnf-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy. Exp. Neurol. 178 2 (2002) 150-164
    • (2002) Exp. Neurol. , vol.178 , Issue.2 , pp. 150-164
    • Liu, Y.1
  • 27
    • 10344248845 scopus 로고    scopus 로고
    • Cell therapy for neuropathic pain in spinal cord injuries
    • Eaton M. Cell therapy for neuropathic pain in spinal cord injuries. Expert Opin. Biol. Ther. 4 12 (2004) 1861-1869
    • (2004) Expert Opin. Biol. Ther. , vol.4 , Issue.12 , pp. 1861-1869
    • Eaton, M.1
  • 28
    • 0035148507 scopus 로고    scopus 로고
    • Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage
    • Cao Q.L., et al. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp. Neurol. 167 1 (2001) 48-58
    • (2001) Exp. Neurol. , vol.167 , Issue.1 , pp. 48-58
    • Cao, Q.L.1
  • 29
    • 0000635530 scopus 로고    scopus 로고
    • Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants
    • Ramon-Cueto A., et al. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J. Neurosci. 18 10 (1998) 3803-3815
    • (1998) J. Neurosci. , vol.18 , Issue.10 , pp. 3803-3815
    • Ramon-Cueto, A.1
  • 30
    • 0033759861 scopus 로고    scopus 로고
    • Olfactory ensheathing cells: bridging the gap in spinal cord injury
    • Bartolomei J.C., and Greer C.A. Olfactory ensheathing cells: bridging the gap in spinal cord injury. Neurosurgery 47 5 (2000) 1057-1069
    • (2000) Neurosurgery , vol.47 , Issue.5 , pp. 1057-1069
    • Bartolomei, J.C.1    Greer, C.A.2
  • 31
    • 33646341818 scopus 로고    scopus 로고
    • Olfactory ensheathing cells: ripples of an incoming tide?
    • Ibrahim A., et al. Olfactory ensheathing cells: ripples of an incoming tide?. Lancet Neurol. 5 5 (2006) 453-457
    • (2006) Lancet Neurol. , vol.5 , Issue.5 , pp. 453-457
    • Ibrahim, A.1
  • 32
    • 33746035288 scopus 로고    scopus 로고
    • Interaction of olfactory ensheathing cells with astrocytes may be the key to repair of tract injuries in the spinal cord: the 'pathway hypothesis'
    • Li Y., et al. Interaction of olfactory ensheathing cells with astrocytes may be the key to repair of tract injuries in the spinal cord: the 'pathway hypothesis'. J. Neurocytol. 34 3-5 (2005) 343-351
    • (2005) J. Neurocytol. , vol.34 , Issue.3-5 , pp. 343-351
    • Li, Y.1
  • 33
    • 14944339732 scopus 로고    scopus 로고
    • Controversial treatments for spinal-cord injuries
    • Curt A., and Dietz V. Controversial treatments for spinal-cord injuries. Lancet 365 9462 (2005) 841
    • (2005) Lancet , vol.365 , Issue.9462 , pp. 841
    • Curt, A.1    Dietz, V.2
  • 34
    • 33747619823 scopus 로고    scopus 로고
    • olfactory mucosa autografts in human spinal cord injury : a pilot study
    • Lima C., et al. olfactory mucosa autografts in human spinal cord injury : a pilot study. J spinal cord med. 29 3 (2006) 191-203
    • (2006) J spinal cord med. , vol.29 , Issue.3 , pp. 191-203
    • Lima, C.1
  • 35
    • 28544446960 scopus 로고    scopus 로고
    • Autologous olfactory ensheathing cell transplantation in human SCI
    • Feron F., et al. Autologous olfactory ensheathing cell transplantation in human SCI. Brain dec 128 (2005) 2951-2960
    • (2005) Brain dec , vol.128 , pp. 2951-2960
    • Feron, F.1
  • 36
    • 0037214454 scopus 로고    scopus 로고
    • Therapeutic vaccination for spinal cord injury: helping the body to cure itself
    • Hauben E., and Schwartz M. Therapeutic vaccination for spinal cord injury: helping the body to cure itself. Trends Pharmacol. Sci. 24 1 (2003) 7-12
    • (2003) Trends Pharmacol. Sci. , vol.24 , Issue.1 , pp. 7-12
    • Hauben, E.1    Schwartz, M.2
  • 37
    • 18944395540 scopus 로고    scopus 로고
    • Long-term body-weight-supported treadmill training and subsequent follow-up in persons with chronic sci: effects on functional walking ability and measures of subjective well-being
    • Hicks A.L., et al. Long-term body-weight-supported treadmill training and subsequent follow-up in persons with chronic sci: effects on functional walking ability and measures of subjective well-being. Spinal Cord 43 5 (2005) 291-298
    • (2005) Spinal Cord , vol.43 , Issue.5 , pp. 291-298
    • Hicks, A.L.1
  • 38
    • 33646586378 scopus 로고    scopus 로고
    • Body weight-supported treadmill training in chronic incomplete spinal cord injury: a pilot study evaluating functional health status and quality of life
    • Effing T.W., et al. Body weight-supported treadmill training in chronic incomplete spinal cord injury: a pilot study evaluating functional health status and quality of life. Spinal Cord 44 5 (2006) 287-296
    • (2006) Spinal Cord , vol.44 , Issue.5 , pp. 287-296
    • Effing, T.W.1
  • 39
    • 14044273501 scopus 로고    scopus 로고
    • Diagnosis and prognostication of adult spinal cord injury without radiographic abnormality using magnetic resonance imaging: analysis of 40 patients
    • (discussion 209)
    • Tewari M.K., et al. Diagnosis and prognostication of adult spinal cord injury without radiographic abnormality using magnetic resonance imaging: analysis of 40 patients. Surg. Neurol. 63 3 (2005) 204-209 (discussion 209)
    • (2005) Surg. Neurol. , vol.63 , Issue.3 , pp. 204-209
    • Tewari, M.K.1
  • 40
    • 0141627487 scopus 로고    scopus 로고
    • Management of urinary tract infection in patients with spinal cord injuries
    • Garcia Leoni M.E., and Esclarin De Ruz A. Management of urinary tract infection in patients with spinal cord injuries. Clin. Microbiol. Infect. 9 8 (2003) 780-785
    • (2003) Clin. Microbiol. Infect. , vol.9 , Issue.8 , pp. 780-785
    • Garcia Leoni, M.E.1    Esclarin De Ruz, A.2
  • 41
    • 25844504685 scopus 로고    scopus 로고
    • The clinical problems in cardiovascular control following spinal cord injury: an overview
    • Krassioukov A., and Claydon V.E. The clinical problems in cardiovascular control following spinal cord injury: an overview. Prog. Brain Res. 152 (2006) 223-229
    • (2006) Prog. Brain Res. , vol.152 , pp. 223-229
    • Krassioukov, A.1    Claydon, V.E.2
  • 42
    • 6344251619 scopus 로고    scopus 로고
    • Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada
    • Steeves J., et al. Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada. Spinal Cord 42 10 (2004) 591-597
    • (2004) Spinal Cord , vol.42 , Issue.10 , pp. 591-597
    • Steeves, J.1
  • 43
    • 23944498068 scopus 로고    scopus 로고
    • Recommended guidelines for studies of human subjects with spinal cord injury
    • Anderson D.K., et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord 43 8 (2005) 453-458
    • (2005) Spinal Cord , vol.43 , Issue.8 , pp. 453-458
    • Anderson, D.K.1
  • 44
    • 0033953033 scopus 로고    scopus 로고
    • Neurosteroids: biosynthesis and function of these novel neuromodulators
    • Compagnone N.A., and Mellon S.H. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front. Neuroendocrinol. 21 (2000) 1-60
    • (2000) Front. Neuroendocrinol. , vol.21 , pp. 1-60
    • Compagnone, N.A.1    Mellon, S.H.2
  • 45
    • 33646675132 scopus 로고    scopus 로고
    • The biological actions of dehydroepiandrosterone involves multiple receptors
    • Webb S.J., et al. The biological actions of dehydroepiandrosterone involves multiple receptors. Drug Metab. Rev. 38 1-2 (2006) 89-116
    • (2006) Drug Metab. Rev. , vol.38 , Issue.1-2 , pp. 89-116
    • Webb, S.J.1
  • 46
    • 0034648042 scopus 로고    scopus 로고
    • Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia
    • Marx C.E., et al. Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia. Brain Res. 871 1 (2000) 104-112
    • (2000) Brain Res. , vol.871 , Issue.1 , pp. 104-112
    • Marx, C.E.1
  • 47
    • 4043096873 scopus 로고    scopus 로고
    • The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mrna expression in primary hippocampal and astrocyte cultures
    • Gubba E.M., et al. The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mrna expression in primary hippocampal and astrocyte cultures. Brain Res. Mol. Brain Res. 127 1-2 (2004) 48-59
    • (2004) Brain Res. Mol. Brain Res. , vol.127 , Issue.1-2 , pp. 48-59
    • Gubba, E.M.1
  • 48
    • 0029855902 scopus 로고    scopus 로고
    • Regulation of the immune response by dehydroepiandrosterone and its metabolites
    • Loria R.M., et al. Regulation of the immune response by dehydroepiandrosterone and its metabolites. J. Endocrinol. 150 Suppl. (1996) S209-S220
    • (1996) J. Endocrinol. , vol.150 , Issue.SUPPL
    • Loria, R.M.1
  • 49
    • 0030067298 scopus 로고    scopus 로고
    • Dehydroepiandrosterone modulation of lipopolysaccharide-stimulated monocyte cytotoxicity
    • Mclachlan J.A., et al. Dehydroepiandrosterone modulation of lipopolysaccharide-stimulated monocyte cytotoxicity. J. Immunol. 156 1 (1996) 328-335
    • (1996) J. Immunol. , vol.156 , Issue.1 , pp. 328-335
    • Mclachlan, J.A.1
  • 50
    • 0032539540 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (dhea) and dhea-sulfate (dheas) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity
    • Kimonides V.G., et al. Dehydroepiandrosterone (dhea) and dhea-sulfate (dheas) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 95 4 (1998) 1852-1857
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.4 , pp. 1852-1857
    • Kimonides, V.G.1
  • 51
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (dhea) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S., et al. Dehydroepiandrosterone (dhea) protects hippocampal cells from oxidative stress-induced damage. Brain Res. Mol. Brain Res. 66 1-2 (1999) 35-41
    • (1999) Brain Res. Mol. Brain Res. , vol.66 , Issue.1-2 , pp. 35-41
    • Bastianetto, S.1
  • 52
    • 0034670008 scopus 로고    scopus 로고
    • Dehydroepiandrosterone inhibits microglial nitric oxide production in a stimulus-specific manner
    • Barger S.W., et al. Dehydroepiandrosterone inhibits microglial nitric oxide production in a stimulus-specific manner. J. Neurosci. Res. 62 4 (2000) 503-509
    • (2000) J. Neurosci. Res. , vol.62 , Issue.4 , pp. 503-509
    • Barger, S.W.1
  • 53
    • 0032516063 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development
    • Compagnone N.A., and Mellon S.H. Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development. Proc. Natl. Acad. Sci. U.S.A. 95 April (1998) 4678-4683
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.April , pp. 4678-4683
    • Compagnone, N.A.1    Mellon, S.H.2
  • 54
    • 4344631779 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone and flutamide on hippocampal ca1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure
    • Maclusky N.J., et al. Effects of dehydroepiandrosterone and flutamide on hippocampal ca1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure. Endocrinology 145 9 (2004) 4154-4161
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4154-4161
    • Maclusky, N.J.1
  • 55
    • 1542297733 scopus 로고    scopus 로고
    • Mitotic and neurogenic effects of dehydroepiandrosterone (dhea) on human neural stem cell cultures derived from the fetal cortex
    • Suzuki M., et al. Mitotic and neurogenic effects of dehydroepiandrosterone (dhea) on human neural stem cell cultures derived from the fetal cortex. Proc. Natl. Acad. Sci. U.S.A. 101 9 (2004) 3202-3207
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.9 , pp. 3202-3207
    • Suzuki, M.1
  • 56
    • 0028810283 scopus 로고
    • Steroidogenic enzyme p450c17 is expressed in the embryonic central nervous system
    • Compagnone N.A., et al. Steroidogenic enzyme p450c17 is expressed in the embryonic central nervous system. Endocrinology 136 11 (1995) 5212-5223
    • (1995) Endocrinology , vol.136 , Issue.11 , pp. 5212-5223
    • Compagnone, N.A.1
  • 57
    • 0842312975 scopus 로고    scopus 로고
    • Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse
    • Fiore C., et al. Treatment with the neurosteroid dehydroepiandrosterone promotes recovery of motor behavior after moderate contusive spinal cord injury in the mouse. J. Neurosci. Res. 75 3 (2004) 391-400
    • (2004) J. Neurosci. Res. , vol.75 , Issue.3 , pp. 391-400
    • Fiore, C.1
  • 58
    • 27644545752 scopus 로고    scopus 로고
    • Differential expression of cell fate determinants in neurons and glial cells of adult mouse spinal cord after compression injury
    • Chen J., et al. Differential expression of cell fate determinants in neurons and glial cells of adult mouse spinal cord after compression injury. Eur. J. Neurosci. 22 8 (2005) 1895-1906
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.8 , pp. 1895-1906
    • Chen, J.1
  • 59
    • 0033570133 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats
    • Thomas A.J., et al. Progesterone is neuroprotective after acute experimental spinal cord trauma in rats. Spine 24 20 (1999) 2134-2138
    • (1999) Spine , vol.24 , Issue.20 , pp. 2134-2138
    • Thomas, A.J.1
  • 60
    • 18144404635 scopus 로고    scopus 로고
    • Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons
    • Gonzalez S.L., et al. Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons. J. Steroid Biochem. Mol. Biol. 94 1-3 (2005) 143-149
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.94 , Issue.1-3 , pp. 143-149
    • Gonzalez, S.L.1
  • 61
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • He J., et al. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp. Neurol. 189 2 (2004) 404-412
    • (2004) Exp. Neurol. , vol.189 , Issue.2 , pp. 404-412
    • He, J.1
  • 62
    • 0347624603 scopus 로고    scopus 로고
    • Bladder function after incomplete spinal cord injury in mice: quantifiable outcomes associated with bladder function and efficiency of dehydroepiandrosterone as a therapeutic adjunct
    • Mure P.Y., et al. Bladder function after incomplete spinal cord injury in mice: quantifiable outcomes associated with bladder function and efficiency of dehydroepiandrosterone as a therapeutic adjunct. J. Neurosurg. 100 Suppl. Spine 1 (2004) 56-61
    • (2004) J. Neurosurg. , vol.100 , Issue.SUPPL. Spine 1 , pp. 56-61
    • Mure, P.Y.1
  • 63
    • 0032080156 scopus 로고    scopus 로고
    • Developmental and injury induced plasticity in the micturition reflex pathway
    • De Groat W.C., et al. Developmental and injury induced plasticity in the micturition reflex pathway. Behav. Brain Res. 92 2 (1998) 127-140
    • (1998) Behav. Brain Res. , vol.92 , Issue.2 , pp. 127-140
    • De Groat, W.C.1
  • 64
    • 0027256437 scopus 로고
    • Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate
    • Yamada T., et al. Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 73 4 (1993) 673-686
    • (1993) Cell , vol.73 , Issue.4 , pp. 673-686
    • Yamada, T.1
  • 65
    • 0033613253 scopus 로고    scopus 로고
    • Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched
    • Fuse N., et al. Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched. Proc. Natl. Acad. Sci. U.S.A. 96 20 (1999) 10992-10999
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , Issue.20 , pp. 10992-10999
    • Fuse, N.1
  • 66
    • 0034646625 scopus 로고    scopus 로고
    • Mapping sonic hedgehog-receptor interactions by steric interference
    • Pepinsky R.B., et al. Mapping sonic hedgehog-receptor interactions by steric interference. J. Biol. Chem. 275 15 (2000) 10995-11001
    • (2000) J. Biol. Chem. , vol.275 , Issue.15 , pp. 10995-11001
    • Pepinsky, R.B.1
  • 67
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso D.M., et al. A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12 1 (1995) 1-21
    • (1995) J. Neurotrauma , vol.12 , Issue.1 , pp. 1-21
    • Basso, D.M.1


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